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Juvenile Nasopharyngeal Angiofibroma: Case report with review on role of imaging in diagnosis.

Gupta S, Gupta S, Ghosh S, Narang P - Contemp Clin Dent (2015 Jan-Mar)

Bottom Line: It was supplied by the right external carotid artery.Patient was referred to the department of neurosurgery for further management.The diagnosis at an early stage is important because it is associated with high risk of morbidity, but advances in imaging, and surgical methods of treatment have changed the sites associated with high risk of morbidity.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Science, New Delhi, India.

ABSTRACT
Juvenile nasopharyngeal angiofibroma is a locally aggressive benign vascular neoplasm, composed of vasogenic and myofibroblastic elements, accounts for 0.05-0.5% of all the head and neck neoplasms. There are very few case reports of nasopharyngeal angiofibroma involving the oral cavity; we report a case involving both the maxilla and mandible in a 17-year-old patient who reported with a large firm swelling on right side of face with recurrent epistaxis and headache. Magnetic resonance angiography revealed a large lobulated enhancing soft tissue mass, which was hypointense on T1-weighted image and heterogeneously hyperintense on T2-weighted image causing expansion of pterygopalatine fossa and sphenopalatine foramen with extension into the sphenoid sinus, ethmoid air cells, right nasal cavity, right infratemporal fossa and right maxillary sinus with remodeling of right zygomatic arch and part of body and ramus of mandible. It was supplied by the right external carotid artery. Patient was referred to the department of neurosurgery for further management. The diagnosis at an early stage is important because it is associated with high risk of morbidity, but advances in imaging, and surgical methods of treatment have changed the sites associated with high risk of morbidity.

No MeSH data available.


Related in: MedlinePlus

Intraoral photograph of the patient showing generalized brown discoloration of teeth lobulated surface of right buccal mucosa
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Figure 2: Intraoral photograph of the patient showing generalized brown discoloration of teeth lobulated surface of right buccal mucosa

Mentions: Intraoral examination [Figure 2] revealed generalized brownish discoloration of teeth in a linear fashion along the cervical third of teeth with high arched palate. The buccal mucosa on the right side was swollen and lobulated extending from the corner of the mouth to the ramus of mandible with indentations on its surface. An ulcer was present in relation to maxillary right first molar, which had everted margins and an erythematous surface about 1 cm in size. Based on history and clinical findings, a provisional diagnosis of benign soft tissue tumor (nonodontogenic) was given. However, benign tumor of the parotid gland, low grade malignancy of parotid gland and lymphoma were considered as the other differentials. Routine hematological investigations were found to be within the normal limits. Fine-needle aspiration of the swelling and the lymph node was performed, which revealed only blood.


Juvenile Nasopharyngeal Angiofibroma: Case report with review on role of imaging in diagnosis.

Gupta S, Gupta S, Ghosh S, Narang P - Contemp Clin Dent (2015 Jan-Mar)

Intraoral photograph of the patient showing generalized brown discoloration of teeth lobulated surface of right buccal mucosa
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4319355&req=5

Figure 2: Intraoral photograph of the patient showing generalized brown discoloration of teeth lobulated surface of right buccal mucosa
Mentions: Intraoral examination [Figure 2] revealed generalized brownish discoloration of teeth in a linear fashion along the cervical third of teeth with high arched palate. The buccal mucosa on the right side was swollen and lobulated extending from the corner of the mouth to the ramus of mandible with indentations on its surface. An ulcer was present in relation to maxillary right first molar, which had everted margins and an erythematous surface about 1 cm in size. Based on history and clinical findings, a provisional diagnosis of benign soft tissue tumor (nonodontogenic) was given. However, benign tumor of the parotid gland, low grade malignancy of parotid gland and lymphoma were considered as the other differentials. Routine hematological investigations were found to be within the normal limits. Fine-needle aspiration of the swelling and the lymph node was performed, which revealed only blood.

Bottom Line: It was supplied by the right external carotid artery.Patient was referred to the department of neurosurgery for further management.The diagnosis at an early stage is important because it is associated with high risk of morbidity, but advances in imaging, and surgical methods of treatment have changed the sites associated with high risk of morbidity.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Science, New Delhi, India.

ABSTRACT
Juvenile nasopharyngeal angiofibroma is a locally aggressive benign vascular neoplasm, composed of vasogenic and myofibroblastic elements, accounts for 0.05-0.5% of all the head and neck neoplasms. There are very few case reports of nasopharyngeal angiofibroma involving the oral cavity; we report a case involving both the maxilla and mandible in a 17-year-old patient who reported with a large firm swelling on right side of face with recurrent epistaxis and headache. Magnetic resonance angiography revealed a large lobulated enhancing soft tissue mass, which was hypointense on T1-weighted image and heterogeneously hyperintense on T2-weighted image causing expansion of pterygopalatine fossa and sphenopalatine foramen with extension into the sphenoid sinus, ethmoid air cells, right nasal cavity, right infratemporal fossa and right maxillary sinus with remodeling of right zygomatic arch and part of body and ramus of mandible. It was supplied by the right external carotid artery. Patient was referred to the department of neurosurgery for further management. The diagnosis at an early stage is important because it is associated with high risk of morbidity, but advances in imaging, and surgical methods of treatment have changed the sites associated with high risk of morbidity.

No MeSH data available.


Related in: MedlinePlus