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Atypical post kala azar dermal leishmaniasis with "muzzle area" swelling.

Arora S, Bal AS, Baveja S, Sood A, Rathi KR, Patil P - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: A 50-year-old male presented with recurrent swelling of the muzzle area of the face with history of low-grade intermittent fever of 3 year duration managed variously with antibiotics, systemic steroids, and antituberculous therapy.Immunochromatography test for rK 39 antigen and polymerase chain reaction for leishmania was positive.He was diagnosed as a case of post kala azar dermal leishmaniasis, managed with injection sodium stibogluconate and followed-up thereafter.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin, Army College of Medical Sciences and Base Hospital, Cantt, New Delhi, India.

ABSTRACT
A 50-year-old male presented with recurrent swelling of the muzzle area of the face with history of low-grade intermittent fever of 3 year duration managed variously with antibiotics, systemic steroids, and antituberculous therapy. Skin biopsy revealed a granulomatous infiltration negative for acid-fast bacilli and leishmania donovan bodies. Immunochromatography test for rK 39 antigen and polymerase chain reaction for leishmania was positive. He was diagnosed as a case of post kala azar dermal leishmaniasis, managed with injection sodium stibogluconate and followed-up thereafter.

No MeSH data available.


Related in: MedlinePlus

Well-defined swelling of the muzzle area with swelling of the lips (pretreatment) and posttreatment (inset)
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Figure 1: Well-defined swelling of the muzzle area with swelling of the lips (pretreatment) and posttreatment (inset)

Mentions: A 50-year-old male presented with history of recurrent perioral swelling for the past 1 and half years. He was asymptomatic for 1 and a half years back when he initially noticed a small swelling on the right side of upper lip which progressively involved the entire upper lip and later the peri-oral area, over the next 6 months [Figure 1], to remit partially on treatment with antibiotics only to relapse again. He was managed at various centers with doxycycline for rosacea, antituberculous therapy for 6 months for lupus vulgaris, as well as prednisolone for Melkerson Rosenthal syndrome. The differentials entertained as per his records were rosacea, lupus vulgaris, cheilitis granulomatosis, and Melkerson Rosenthal syndrome.


Atypical post kala azar dermal leishmaniasis with "muzzle area" swelling.

Arora S, Bal AS, Baveja S, Sood A, Rathi KR, Patil P - Indian J Dermatol (2015 Jan-Feb)

Well-defined swelling of the muzzle area with swelling of the lips (pretreatment) and posttreatment (inset)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318072&req=5

Figure 1: Well-defined swelling of the muzzle area with swelling of the lips (pretreatment) and posttreatment (inset)
Mentions: A 50-year-old male presented with history of recurrent perioral swelling for the past 1 and half years. He was asymptomatic for 1 and a half years back when he initially noticed a small swelling on the right side of upper lip which progressively involved the entire upper lip and later the peri-oral area, over the next 6 months [Figure 1], to remit partially on treatment with antibiotics only to relapse again. He was managed at various centers with doxycycline for rosacea, antituberculous therapy for 6 months for lupus vulgaris, as well as prednisolone for Melkerson Rosenthal syndrome. The differentials entertained as per his records were rosacea, lupus vulgaris, cheilitis granulomatosis, and Melkerson Rosenthal syndrome.

Bottom Line: A 50-year-old male presented with recurrent swelling of the muzzle area of the face with history of low-grade intermittent fever of 3 year duration managed variously with antibiotics, systemic steroids, and antituberculous therapy.Immunochromatography test for rK 39 antigen and polymerase chain reaction for leishmania was positive.He was diagnosed as a case of post kala azar dermal leishmaniasis, managed with injection sodium stibogluconate and followed-up thereafter.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin, Army College of Medical Sciences and Base Hospital, Cantt, New Delhi, India.

ABSTRACT
A 50-year-old male presented with recurrent swelling of the muzzle area of the face with history of low-grade intermittent fever of 3 year duration managed variously with antibiotics, systemic steroids, and antituberculous therapy. Skin biopsy revealed a granulomatous infiltration negative for acid-fast bacilli and leishmania donovan bodies. Immunochromatography test for rK 39 antigen and polymerase chain reaction for leishmania was positive. He was diagnosed as a case of post kala azar dermal leishmaniasis, managed with injection sodium stibogluconate and followed-up thereafter.

No MeSH data available.


Related in: MedlinePlus