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Poroma with sebaceous differentiation: dermoscopy for the diagnosis of skin tumor with sebaceous differentiation.

Ito T, Yoshida Y, Furue M, Yamamoto O - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: A 38-year-old Japanese female presented with a 2-year history of a slow-growing nodule on her left forearm.Dermoscopically, fine hairpin-like vessels, beige lobular structures were seen in the nodule.Many small yellow dots were scattered between beige lobular structures, giving orange-beige in color as a whole.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine of Sensory and Motor Organs, Division of Dermatology, Faculty of Medicine, Tottori University, Tottori, Japan ; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

ABSTRACT
Although divergent adnexal differentiations are occasionally seen in poroma, poroma with sebaceous differentiation is extremely rare. We present here the second case of dermoscopy on poroma with sebaceous differentiation. A 38-year-old Japanese female presented with a 2-year history of a slow-growing nodule on her left forearm. Dermoscopically, fine hairpin-like vessels, beige lobular structures were seen in the nodule. Many small yellow dots were scattered between beige lobular structures, giving orange-beige in color as a whole. On the basis of histopathologic findings, a diagnosis of poroma with sebaceous differentiation was made. Some sebaceous tumors are known to exhibit yellowish structures on dermoscopy. Tumors with sebaceous differentiation, as well as conventional sebaceous tumors, can show yellow structures on dermoscopy.

No MeSH data available.


Related in: MedlinePlus

H and E, ×400. Sebaceous lobules in the poroid nest
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Figure 5: H and E, ×400. Sebaceous lobules in the poroid nest

Mentions: A 38-year-old Japanese female presented with a 2-year history of a slow-growing nodule on her left forearm. Physical examination revealed a slightly elevated pink nodule of 4 mm in size [Figure 1]. Dermoscopically, fine hairpin-like vessels, beige lobular structures were seen in the nodule. Of note, many small yellow dots were scattered between beige lobular structures. Some of them were too small to be noted as dots, giving orange-beige in color as a whole [Figure 2]. Histopathologically, the lesion consisted of well-defined nests of monomorphous cuboidal or oval poroid cells with oval nuclei and eosinophilic cytoplasm connected with the overlying epidermis [Figure 3]. Tubular structures formed by cuticular cells and intracytoplasmic canaliculi in those cells were also present [Figure 4]. Poroid or cuticular cells were observed in more than 65% area of the tumor cell nests. Sebaceous lobules of various sizes were noted in the poroid nest [Figure 5]. No atypical mitoses were noted. Based on these findings, a diagnosis of poroma with sebaceous differentiation was made.


Poroma with sebaceous differentiation: dermoscopy for the diagnosis of skin tumor with sebaceous differentiation.

Ito T, Yoshida Y, Furue M, Yamamoto O - Indian J Dermatol (2015 Jan-Feb)

H and E, ×400. Sebaceous lobules in the poroid nest
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318071&req=5

Figure 5: H and E, ×400. Sebaceous lobules in the poroid nest
Mentions: A 38-year-old Japanese female presented with a 2-year history of a slow-growing nodule on her left forearm. Physical examination revealed a slightly elevated pink nodule of 4 mm in size [Figure 1]. Dermoscopically, fine hairpin-like vessels, beige lobular structures were seen in the nodule. Of note, many small yellow dots were scattered between beige lobular structures. Some of them were too small to be noted as dots, giving orange-beige in color as a whole [Figure 2]. Histopathologically, the lesion consisted of well-defined nests of monomorphous cuboidal or oval poroid cells with oval nuclei and eosinophilic cytoplasm connected with the overlying epidermis [Figure 3]. Tubular structures formed by cuticular cells and intracytoplasmic canaliculi in those cells were also present [Figure 4]. Poroid or cuticular cells were observed in more than 65% area of the tumor cell nests. Sebaceous lobules of various sizes were noted in the poroid nest [Figure 5]. No atypical mitoses were noted. Based on these findings, a diagnosis of poroma with sebaceous differentiation was made.

Bottom Line: A 38-year-old Japanese female presented with a 2-year history of a slow-growing nodule on her left forearm.Dermoscopically, fine hairpin-like vessels, beige lobular structures were seen in the nodule.Many small yellow dots were scattered between beige lobular structures, giving orange-beige in color as a whole.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine of Sensory and Motor Organs, Division of Dermatology, Faculty of Medicine, Tottori University, Tottori, Japan ; Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

ABSTRACT
Although divergent adnexal differentiations are occasionally seen in poroma, poroma with sebaceous differentiation is extremely rare. We present here the second case of dermoscopy on poroma with sebaceous differentiation. A 38-year-old Japanese female presented with a 2-year history of a slow-growing nodule on her left forearm. Dermoscopically, fine hairpin-like vessels, beige lobular structures were seen in the nodule. Many small yellow dots were scattered between beige lobular structures, giving orange-beige in color as a whole. On the basis of histopathologic findings, a diagnosis of poroma with sebaceous differentiation was made. Some sebaceous tumors are known to exhibit yellowish structures on dermoscopy. Tumors with sebaceous differentiation, as well as conventional sebaceous tumors, can show yellow structures on dermoscopy.

No MeSH data available.


Related in: MedlinePlus