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Solitary pilar leiomyoma of the nasal dorsum: case report and literature review.

Hoyt BS, Tschen JA, Cohen PR - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: Cutaneous leiomyoma is an infrequently occurring benign tumor that arises from smooth muscle in the skin.Pilar leiomyoma, a subtype of cutaneous leiomyoma, arises from the arrector pili muscle associated with hair follicles.Pilar leiomyoma, particularly in the head and neck region, is rare and frequently misdiagnosed.

View Article: PubMed Central - PubMed

Affiliation: Medical School, University of Texas Medical School at Houston, Houston, Texas, United States of America.

ABSTRACT
Cutaneous leiomyoma is an infrequently occurring benign tumor that arises from smooth muscle in the skin. Pilar leiomyoma, a subtype of cutaneous leiomyoma, arises from the arrector pili muscle associated with hair follicles. Pilar leiomyoma, particularly in the head and neck region, is rare and frequently misdiagnosed. We report one patient who developed pilar leiomyoma of the nasal dorsum, explore the differential diagnosis and review the characteristics of previously reported individuals with pilar leiomyoma of the nasal dorsum.

No MeSH data available.


Related in: MedlinePlus

A low magnification view (a) of the biopsy specimen from the nasal dorsum shows a plaque-like proliferation of cells, which are present in the mid and deep reticular dermis. Closer view (b) abundant mucin between the bundles of cells. The high magnification view (c) the cells have blunt-tipped, cigar-shaped nuclei without atypia or mitoses. These findings are suggestive of a pilar leiomyoma (H and E, a = ×2, b = ×4, c = ×20)
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Figure 3: A low magnification view (a) of the biopsy specimen from the nasal dorsum shows a plaque-like proliferation of cells, which are present in the mid and deep reticular dermis. Closer view (b) abundant mucin between the bundles of cells. The high magnification view (c) the cells have blunt-tipped, cigar-shaped nuclei without atypia or mitoses. These findings are suggestive of a pilar leiomyoma (H and E, a = ×2, b = ×4, c = ×20)

Mentions: A healthy 24-year-old female patient presented with a 5 mm × 7 mm red dermal nodule on the bridge of her nose [Figures 1 and 2]. The lesion had been present for 2 years and occasionally itched. The size was relatively stable, increasing slightly when she scratched the nodule and then returning to baseline. There was no personal or family history of uterine leiomyomas. A 2 mm punch biopsy revealed smooth muscle bundles forming a plaque in the dermis [Figure 3]. The bundles of tissue were separated by abundant mucin and immunoperoxidase staining confirmed the presence of smooth muscle actin (SMA) [Figure 4]. These findings were consistent with a pilar leiomyoma of the nasal dorsum.


Solitary pilar leiomyoma of the nasal dorsum: case report and literature review.

Hoyt BS, Tschen JA, Cohen PR - Indian J Dermatol (2015 Jan-Feb)

A low magnification view (a) of the biopsy specimen from the nasal dorsum shows a plaque-like proliferation of cells, which are present in the mid and deep reticular dermis. Closer view (b) abundant mucin between the bundles of cells. The high magnification view (c) the cells have blunt-tipped, cigar-shaped nuclei without atypia or mitoses. These findings are suggestive of a pilar leiomyoma (H and E, a = ×2, b = ×4, c = ×20)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318070&req=5

Figure 3: A low magnification view (a) of the biopsy specimen from the nasal dorsum shows a plaque-like proliferation of cells, which are present in the mid and deep reticular dermis. Closer view (b) abundant mucin between the bundles of cells. The high magnification view (c) the cells have blunt-tipped, cigar-shaped nuclei without atypia or mitoses. These findings are suggestive of a pilar leiomyoma (H and E, a = ×2, b = ×4, c = ×20)
Mentions: A healthy 24-year-old female patient presented with a 5 mm × 7 mm red dermal nodule on the bridge of her nose [Figures 1 and 2]. The lesion had been present for 2 years and occasionally itched. The size was relatively stable, increasing slightly when she scratched the nodule and then returning to baseline. There was no personal or family history of uterine leiomyomas. A 2 mm punch biopsy revealed smooth muscle bundles forming a plaque in the dermis [Figure 3]. The bundles of tissue were separated by abundant mucin and immunoperoxidase staining confirmed the presence of smooth muscle actin (SMA) [Figure 4]. These findings were consistent with a pilar leiomyoma of the nasal dorsum.

Bottom Line: Cutaneous leiomyoma is an infrequently occurring benign tumor that arises from smooth muscle in the skin.Pilar leiomyoma, a subtype of cutaneous leiomyoma, arises from the arrector pili muscle associated with hair follicles.Pilar leiomyoma, particularly in the head and neck region, is rare and frequently misdiagnosed.

View Article: PubMed Central - PubMed

Affiliation: Medical School, University of Texas Medical School at Houston, Houston, Texas, United States of America.

ABSTRACT
Cutaneous leiomyoma is an infrequently occurring benign tumor that arises from smooth muscle in the skin. Pilar leiomyoma, a subtype of cutaneous leiomyoma, arises from the arrector pili muscle associated with hair follicles. Pilar leiomyoma, particularly in the head and neck region, is rare and frequently misdiagnosed. We report one patient who developed pilar leiomyoma of the nasal dorsum, explore the differential diagnosis and review the characteristics of previously reported individuals with pilar leiomyoma of the nasal dorsum.

No MeSH data available.


Related in: MedlinePlus