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Is frictional lichenoid dermatitis a minor variant of atopic dermatitis or a photodermatosis.

Sardana K, Goel K, Garg VK, Goel A, Khanna D, Grover C, Khurana N - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: The number of cases seen per month was compared with the mean monthly UV index.FLE is probably not associated with atopic dermatitis and is likely to be related to the ambient UV index though a larger cohort with meticulous follow up may be needed to draw a final conclusion.P < 0.05 was considered significant.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.

ABSTRACT

Context: Frictional lichenoid dermatitis.

Background: Frictional lichenoid dermatitis (FLE) is an entity that is probably under diagnosed and has been variably associated with either friction and/or atopy with a distinctive seasonal variation.

Aims and objectives: To study correlation of FLE with UV index and to assess its association with atopic dermatitis.

Materials and methods: A cross sectional analysis of children with FLE was done, over a period of 6 years in two tertiary hospitals. A detailed history and examination was done to assess the features of atopic dermatitis. The number of cases seen per month was compared with the mean monthly UV index. Two-tailed significance tests using Pearson's coefficient of correlation and T-test were used to interpret the data. (P < 0.05).

Results: One hundred seventy-four patients were studied using the UKC criterion 17.2% of the patients had AD while xerosis (40.3%) was the predominant cutaneous finding. The number of patients seen in summer was more than in winter (P < 0.05) but there was no statistical difference between the cases in winter and spring. There was a significant correlation of the number of cases per month with UV index (P = 0.019). Almost 42% of patients gave a history of recurrence.

Conclusions: FLE is probably not associated with atopic dermatitis and is likely to be related to the ambient UV index though a larger cohort with meticulous follow up may be needed to draw a final conclusion.

Statistical analysis used: The Pearson's coefficient of correlation was used for comparing the cases per month with the UV index. The tests of hypothesis used included the paired T-tests. F-test of variance, Welch test, Wilcoxon rank sum test and the Kolmogorov-Smirnov Test. P < 0.05 was considered significant.

No MeSH data available.


Related in: MedlinePlus

(a) Lesions of FLE on the dorsum of the hand. (b) Lesions of FLE in a child localized to the exposed part of the knee. Note the aggregated lesions which occasionally form a plaque
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Figure 5: (a) Lesions of FLE on the dorsum of the hand. (b) Lesions of FLE in a child localized to the exposed part of the knee. Note the aggregated lesions which occasionally form a plaque

Mentions: A total of 174 patients were studied [Table 4], the majority of which were males (64.5%). The morphology was varied with the severity ranging from mild to the severe forms with crusting[26] [Table 3, Figures 2–4]. The commonest site affected was the elbows [Figures 2–4] followed by the dorsum of hands [Figure 5a] and the knee [Figure 5b]. The condition was symptomatic in 33% of cases and in the rest the pruritus was mild to moderate in most cases. Though almost 42% of patients gave a history of recurrence in, only 42 patients could be prospectively followed up over the 7 year study period. Of these patients almost 70% had a second episode in the same season. The period of follow up after the first episode ranged from 1-5 years. None of the patients followed up developed AD on follow-up. Using the UKC criterion[17] out of all the cases seen of FLE only 17.2% of cases had AD while the commonest associated finding was xerosis (40.3%). The rest (42.5%) had no significant abnormality. Histological examination revealed a nonspecific perivascular lymphocytic infiltrate in the patients who were biopsied (n = 30).


Is frictional lichenoid dermatitis a minor variant of atopic dermatitis or a photodermatosis.

Sardana K, Goel K, Garg VK, Goel A, Khanna D, Grover C, Khurana N - Indian J Dermatol (2015 Jan-Feb)

(a) Lesions of FLE on the dorsum of the hand. (b) Lesions of FLE in a child localized to the exposed part of the knee. Note the aggregated lesions which occasionally form a plaque
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318066&req=5

Figure 5: (a) Lesions of FLE on the dorsum of the hand. (b) Lesions of FLE in a child localized to the exposed part of the knee. Note the aggregated lesions which occasionally form a plaque
Mentions: A total of 174 patients were studied [Table 4], the majority of which were males (64.5%). The morphology was varied with the severity ranging from mild to the severe forms with crusting[26] [Table 3, Figures 2–4]. The commonest site affected was the elbows [Figures 2–4] followed by the dorsum of hands [Figure 5a] and the knee [Figure 5b]. The condition was symptomatic in 33% of cases and in the rest the pruritus was mild to moderate in most cases. Though almost 42% of patients gave a history of recurrence in, only 42 patients could be prospectively followed up over the 7 year study period. Of these patients almost 70% had a second episode in the same season. The period of follow up after the first episode ranged from 1-5 years. None of the patients followed up developed AD on follow-up. Using the UKC criterion[17] out of all the cases seen of FLE only 17.2% of cases had AD while the commonest associated finding was xerosis (40.3%). The rest (42.5%) had no significant abnormality. Histological examination revealed a nonspecific perivascular lymphocytic infiltrate in the patients who were biopsied (n = 30).

Bottom Line: The number of cases seen per month was compared with the mean monthly UV index.FLE is probably not associated with atopic dermatitis and is likely to be related to the ambient UV index though a larger cohort with meticulous follow up may be needed to draw a final conclusion.P < 0.05 was considered significant.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.

ABSTRACT

Context: Frictional lichenoid dermatitis.

Background: Frictional lichenoid dermatitis (FLE) is an entity that is probably under diagnosed and has been variably associated with either friction and/or atopy with a distinctive seasonal variation.

Aims and objectives: To study correlation of FLE with UV index and to assess its association with atopic dermatitis.

Materials and methods: A cross sectional analysis of children with FLE was done, over a period of 6 years in two tertiary hospitals. A detailed history and examination was done to assess the features of atopic dermatitis. The number of cases seen per month was compared with the mean monthly UV index. Two-tailed significance tests using Pearson's coefficient of correlation and T-test were used to interpret the data. (P < 0.05).

Results: One hundred seventy-four patients were studied using the UKC criterion 17.2% of the patients had AD while xerosis (40.3%) was the predominant cutaneous finding. The number of patients seen in summer was more than in winter (P < 0.05) but there was no statistical difference between the cases in winter and spring. There was a significant correlation of the number of cases per month with UV index (P = 0.019). Almost 42% of patients gave a history of recurrence.

Conclusions: FLE is probably not associated with atopic dermatitis and is likely to be related to the ambient UV index though a larger cohort with meticulous follow up may be needed to draw a final conclusion.

Statistical analysis used: The Pearson's coefficient of correlation was used for comparing the cases per month with the UV index. The tests of hypothesis used included the paired T-tests. F-test of variance, Welch test, Wilcoxon rank sum test and the Kolmogorov-Smirnov Test. P < 0.05 was considered significant.

No MeSH data available.


Related in: MedlinePlus