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Acne vulgaris and quality of life among young adults in South India.

Durai PC, Nair DG - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: Association between the scores was statistically significant.Age, occupation, marital status, family, and treatment history played a role in affecting the QoL.Diet, smoking, and alcohol did not influence the QoL.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Sexually Transmitted Disease and Leprosy, A. J. Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India.

ABSTRACT

Unlabelled: Acne vulgaris is a chronic condition affecting more than 85% of adolescents and young adults. It is one of the most common diseases affecting humanity and its impact on quality of life (QoL) is important. The impact of acne on QoL in Indian patients remains undocumented. The study was undertaken to detect the impact of acne vulgaris and related factors that may influence the QoL.

Materials and methods: This was a hospital-based, prospective, cross-sectional, prestructured, questionnaire-based study done on 140 consenting individuals, who attended the Dermatology outpatient department. Acne vulgaris was graded using simple grading system. QoL was measured using a combination of skin disease-specific (Dermatological Life Quality Index (DLQI)) and acne-specific (Cardiff Acne Disability Index (CADI)) questionnaires.

Results: Majority of our study population were students (103, 73.6%). Face (139, 99.3%) was the commonest site of acne and comedones 133, 95% were the commonest type of lesion. Most of the individuals 66, 47.1% were observed to have grade 1 acne. The mean DLQI score was 6.91 and the mean CADI score was 5.2. Association between the scores was statistically significant. Age, occupation, marital status, family, and treatment history played a role in affecting the QoL. Diet, smoking, and alcohol did not influence the QoL.

Conclusion: Though acne had impact on patient's QoL, it was less severe in our study. It is important for health professionals to incorporate QoL measurements when managing acne patients to provide better and appropriate care.

No MeSH data available.


Related in: MedlinePlus

Seborrhea with papules over the face
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Figure 7: Seborrhea with papules over the face

Mentions: Acne vulgaris is a chronic inflammatory disease of pilosebaceous unit.[1] It affects 85% of adolescents and young adults.[10] The pathogenesis is attributed to multiple factors such as increased sebum production, follicular hyperkeratinization, proliferation of Propionibacterium acnes within the follicle, alteration of the quality of sebum lipids, regulation of cutaneous steroidogenesis, androgen activity, interaction with neuropeptides, and exhibition of pro- and anti-inflammatory properties. The increased sebum excretion [Figure 6] is a major concurrent event associated with the development of acne.[111] Inflammation plays a key role and may be the primary process in the pathogenesis, led by the perifollicular T-helper cells through IL-1. It also upregulates sebum production through leukotriene B4.[2]


Acne vulgaris and quality of life among young adults in South India.

Durai PC, Nair DG - Indian J Dermatol (2015 Jan-Feb)

Seborrhea with papules over the face
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318060&req=5

Figure 7: Seborrhea with papules over the face
Mentions: Acne vulgaris is a chronic inflammatory disease of pilosebaceous unit.[1] It affects 85% of adolescents and young adults.[10] The pathogenesis is attributed to multiple factors such as increased sebum production, follicular hyperkeratinization, proliferation of Propionibacterium acnes within the follicle, alteration of the quality of sebum lipids, regulation of cutaneous steroidogenesis, androgen activity, interaction with neuropeptides, and exhibition of pro- and anti-inflammatory properties. The increased sebum excretion [Figure 6] is a major concurrent event associated with the development of acne.[111] Inflammation plays a key role and may be the primary process in the pathogenesis, led by the perifollicular T-helper cells through IL-1. It also upregulates sebum production through leukotriene B4.[2]

Bottom Line: Association between the scores was statistically significant.Age, occupation, marital status, family, and treatment history played a role in affecting the QoL.Diet, smoking, and alcohol did not influence the QoL.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Sexually Transmitted Disease and Leprosy, A. J. Institute of Medical Sciences, Kuntikana, Mangalore, Karnataka, India.

ABSTRACT

Unlabelled: Acne vulgaris is a chronic condition affecting more than 85% of adolescents and young adults. It is one of the most common diseases affecting humanity and its impact on quality of life (QoL) is important. The impact of acne on QoL in Indian patients remains undocumented. The study was undertaken to detect the impact of acne vulgaris and related factors that may influence the QoL.

Materials and methods: This was a hospital-based, prospective, cross-sectional, prestructured, questionnaire-based study done on 140 consenting individuals, who attended the Dermatology outpatient department. Acne vulgaris was graded using simple grading system. QoL was measured using a combination of skin disease-specific (Dermatological Life Quality Index (DLQI)) and acne-specific (Cardiff Acne Disability Index (CADI)) questionnaires.

Results: Majority of our study population were students (103, 73.6%). Face (139, 99.3%) was the commonest site of acne and comedones 133, 95% were the commonest type of lesion. Most of the individuals 66, 47.1% were observed to have grade 1 acne. The mean DLQI score was 6.91 and the mean CADI score was 5.2. Association between the scores was statistically significant. Age, occupation, marital status, family, and treatment history played a role in affecting the QoL. Diet, smoking, and alcohol did not influence the QoL.

Conclusion: Though acne had impact on patient's QoL, it was less severe in our study. It is important for health professionals to incorporate QoL measurements when managing acne patients to provide better and appropriate care.

No MeSH data available.


Related in: MedlinePlus