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Remote cutaneous breast carcinoma metastasis mimicking dermatitis.

Navaratnam AV, Chandrasekharan S - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: Cutaneous metastases are more frequently seen in breast cancer than in any other visceral malignancy in women.Medical practitioners should be vigilant of the possibility of unusual presentations of metastatic disease in breast cancer patients with lobular carcinoma presenting as cutaneous lesions mimicking benign dermatological conditions.Herein, we present a case of a 75-year-old woman presenting with cutaneous lobular breast carcinoma metastases on her anterior right leg, which had previously been misdiagnosed as dermatitis for 9 years.

View Article: PubMed Central - PubMed

Affiliation: Breast Surgery Unit, Colchester Hospital University National Health Service Foundation Trust, Colchester, Essex, CO4 5JL, UK.

ABSTRACT
Cutaneous metastases from primary internal malignancies are an uncommon presentation. Cutaneous metastases are more frequently seen in breast cancer than in any other visceral malignancy in women. Medical practitioners should be vigilant of the possibility of unusual presentations of metastatic disease in breast cancer patients with lobular carcinoma presenting as cutaneous lesions mimicking benign dermatological conditions. Herein, we present a case of a 75-year-old woman presenting with cutaneous lobular breast carcinoma metastases on her anterior right leg, which had previously been misdiagnosed as dermatitis for 9 years.

No MeSH data available.


Related in: MedlinePlus

Carcinoma cells in skin biopsy stain positive for estrogen receptors (immunohistochemistry for estrogen receptors, × 1000)
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Figure 3: Carcinoma cells in skin biopsy stain positive for estrogen receptors (immunohistochemistry for estrogen receptors, × 1000)

Mentions: After referral to a dermatologist, punch biopsy revealed an infiltrate of malignant cells consistent with spread from an infiltrating lobular carcinoma of the breast [Figure 2]. Further analysis demonstrated that the metastasis contained over 80% estrogen receptor positive cells [Figure 3]. As a result, the patient was commenced on endocrine treatment in the form of exemestane, an aromatase inhibitor. Computed tomography scan of the thorax, abdomen, and pelvis revealed no other metastasis. On follow-up, 6 months after the diagnosis, the lesion was found to be static and the patient's symptoms had resolved. The patient is currently being monitored in outpatient clinic.


Remote cutaneous breast carcinoma metastasis mimicking dermatitis.

Navaratnam AV, Chandrasekharan S - Indian J Dermatol (2015 Jan-Feb)

Carcinoma cells in skin biopsy stain positive for estrogen receptors (immunohistochemistry for estrogen receptors, × 1000)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318045&req=5

Figure 3: Carcinoma cells in skin biopsy stain positive for estrogen receptors (immunohistochemistry for estrogen receptors, × 1000)
Mentions: After referral to a dermatologist, punch biopsy revealed an infiltrate of malignant cells consistent with spread from an infiltrating lobular carcinoma of the breast [Figure 2]. Further analysis demonstrated that the metastasis contained over 80% estrogen receptor positive cells [Figure 3]. As a result, the patient was commenced on endocrine treatment in the form of exemestane, an aromatase inhibitor. Computed tomography scan of the thorax, abdomen, and pelvis revealed no other metastasis. On follow-up, 6 months after the diagnosis, the lesion was found to be static and the patient's symptoms had resolved. The patient is currently being monitored in outpatient clinic.

Bottom Line: Cutaneous metastases are more frequently seen in breast cancer than in any other visceral malignancy in women.Medical practitioners should be vigilant of the possibility of unusual presentations of metastatic disease in breast cancer patients with lobular carcinoma presenting as cutaneous lesions mimicking benign dermatological conditions.Herein, we present a case of a 75-year-old woman presenting with cutaneous lobular breast carcinoma metastases on her anterior right leg, which had previously been misdiagnosed as dermatitis for 9 years.

View Article: PubMed Central - PubMed

Affiliation: Breast Surgery Unit, Colchester Hospital University National Health Service Foundation Trust, Colchester, Essex, CO4 5JL, UK.

ABSTRACT
Cutaneous metastases from primary internal malignancies are an uncommon presentation. Cutaneous metastases are more frequently seen in breast cancer than in any other visceral malignancy in women. Medical practitioners should be vigilant of the possibility of unusual presentations of metastatic disease in breast cancer patients with lobular carcinoma presenting as cutaneous lesions mimicking benign dermatological conditions. Herein, we present a case of a 75-year-old woman presenting with cutaneous lobular breast carcinoma metastases on her anterior right leg, which had previously been misdiagnosed as dermatitis for 9 years.

No MeSH data available.


Related in: MedlinePlus