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Extra Mammary Paget's Disease: A Rare Case Report.

Sardesai VR, Agarwal TD, Sakhalkar SP - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: A 62-year-old postmenopausal woman presented with extremely pruritic plaque on the perineal skin which progressed gradually over 3 years and did not respond to any topical/systemic steroids, antibiotics, and antifungals.Biopsy showed Paget's cells which were positive for Periodic Acid Schiff and alcian blue stain.Surgical excision was done considering the premalignant potential.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, STD and Leprosy, Bharati Vidyapeeth Medical College, Pune, India.

ABSTRACT
Extramammary Paget's disease is a marginated plaque resembling Paget's disease but occurring in anogenital area, axilla or most commonly on the vulva. A 62-year-old postmenopausal woman presented with extremely pruritic plaque on the perineal skin which progressed gradually over 3 years and did not respond to any topical/systemic steroids, antibiotics, and antifungals. Examination revealed 7 × 8 cm. hypertrophic, verrucous plaque with erosions, and crusts at places. There was no evidence of visceral malignancy. Biopsy showed Paget's cells which were positive for Periodic Acid Schiff and alcian blue stain. Surgical excision was done considering the premalignant potential.

No MeSH data available.


Related in: MedlinePlus

Lesion on perineal area
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Figure 1: Lesion on perineal area

Mentions: Dermatological examination revealed approximately a 7 × 8 cm well-marginated, hypertrophic, and verrucous plaque in the perineal region. [Figure 1] At places grayish crusts with shallow erosions and a purulent discharge was seen. [Figure 2] There was no similar lesion anywhere else on the body. Proctoscopy examination was within normal limits. There was no regional lymphadenopathy.


Extra Mammary Paget's Disease: A Rare Case Report.

Sardesai VR, Agarwal TD, Sakhalkar SP - Indian J Dermatol (2015 Jan-Feb)

Lesion on perineal area
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318038&req=5

Figure 1: Lesion on perineal area
Mentions: Dermatological examination revealed approximately a 7 × 8 cm well-marginated, hypertrophic, and verrucous plaque in the perineal region. [Figure 1] At places grayish crusts with shallow erosions and a purulent discharge was seen. [Figure 2] There was no similar lesion anywhere else on the body. Proctoscopy examination was within normal limits. There was no regional lymphadenopathy.

Bottom Line: A 62-year-old postmenopausal woman presented with extremely pruritic plaque on the perineal skin which progressed gradually over 3 years and did not respond to any topical/systemic steroids, antibiotics, and antifungals.Biopsy showed Paget's cells which were positive for Periodic Acid Schiff and alcian blue stain.Surgical excision was done considering the premalignant potential.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, STD and Leprosy, Bharati Vidyapeeth Medical College, Pune, India.

ABSTRACT
Extramammary Paget's disease is a marginated plaque resembling Paget's disease but occurring in anogenital area, axilla or most commonly on the vulva. A 62-year-old postmenopausal woman presented with extremely pruritic plaque on the perineal skin which progressed gradually over 3 years and did not respond to any topical/systemic steroids, antibiotics, and antifungals. Examination revealed 7 × 8 cm. hypertrophic, verrucous plaque with erosions, and crusts at places. There was no evidence of visceral malignancy. Biopsy showed Paget's cells which were positive for Periodic Acid Schiff and alcian blue stain. Surgical excision was done considering the premalignant potential.

No MeSH data available.


Related in: MedlinePlus