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Ulcerative lupus vulgaris over nose, leading to cosmetic deformity.

Nair PA, Mehta MJ, Patel BB - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: Lupus vulgaris (LV), is a chronic and progressive form of secondary cutaneous tuberculosis.In India, it is commonly seen over buttocks, thighs, and legs whereas involvement of nose is quite rare.A case of LV over nose in a young male with ulceration is reported who responded well to anti-tubercular therapy, but left with scarring of nose, which could have been prevented if adequate awareness regarding extra-pulmonary cases would have been practiced.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin and V.D., Pramukhswami Medical College, Karamsad, Gujarat, India.

ABSTRACT
Lupus vulgaris (LV), is a chronic and progressive form of secondary cutaneous tuberculosis. In India, it is commonly seen over buttocks, thighs, and legs whereas involvement of nose is quite rare. Ulcerative variant particularly over nose causes destruction of cartilage, leading to irreversible deformities and contracture. High-index of suspicion is required for early diagnosis and prevention of cosmetic deformity. A case of LV over nose in a young male with ulceration is reported who responded well to anti-tubercular therapy, but left with scarring of nose, which could have been prevented if adequate awareness regarding extra-pulmonary cases would have been practiced.

No MeSH data available.


Related in: MedlinePlus

Epitheloid cell granuloma composed of langhans type of giant cells (H and E, ×40)
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Figure 2: Epitheloid cell granuloma composed of langhans type of giant cells (H and E, ×40)

Mentions: Laboratory findings were normal except erythrocyte sedimentation rate which was 60 mm/1st hour. X-ray chest was normal. Veneral disease research laboratory and ELISA for HIV were negative. Mantoux test was positive with 23 mm × 18 mm diameter induration and erythema. Ziehl-Neelsen staining didn’t reveal any acid fast bacilli. Deep biopsy taken showed features of LV on H and E, staining. Epidermal atrophy and epitheloid cell granuloma composed of langhans type of giant cells, epitheloid cells and lymphocytes along with intense inflammatory infiltrate was seen in dermis [Figure 2].


Ulcerative lupus vulgaris over nose, leading to cosmetic deformity.

Nair PA, Mehta MJ, Patel BB - Indian J Dermatol (2015 Jan-Feb)

Epitheloid cell granuloma composed of langhans type of giant cells (H and E, ×40)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318033&req=5

Figure 2: Epitheloid cell granuloma composed of langhans type of giant cells (H and E, ×40)
Mentions: Laboratory findings were normal except erythrocyte sedimentation rate which was 60 mm/1st hour. X-ray chest was normal. Veneral disease research laboratory and ELISA for HIV were negative. Mantoux test was positive with 23 mm × 18 mm diameter induration and erythema. Ziehl-Neelsen staining didn’t reveal any acid fast bacilli. Deep biopsy taken showed features of LV on H and E, staining. Epidermal atrophy and epitheloid cell granuloma composed of langhans type of giant cells, epitheloid cells and lymphocytes along with intense inflammatory infiltrate was seen in dermis [Figure 2].

Bottom Line: Lupus vulgaris (LV), is a chronic and progressive form of secondary cutaneous tuberculosis.In India, it is commonly seen over buttocks, thighs, and legs whereas involvement of nose is quite rare.A case of LV over nose in a young male with ulceration is reported who responded well to anti-tubercular therapy, but left with scarring of nose, which could have been prevented if adequate awareness regarding extra-pulmonary cases would have been practiced.

View Article: PubMed Central - PubMed

Affiliation: Department of Skin and V.D., Pramukhswami Medical College, Karamsad, Gujarat, India.

ABSTRACT
Lupus vulgaris (LV), is a chronic and progressive form of secondary cutaneous tuberculosis. In India, it is commonly seen over buttocks, thighs, and legs whereas involvement of nose is quite rare. Ulcerative variant particularly over nose causes destruction of cartilage, leading to irreversible deformities and contracture. High-index of suspicion is required for early diagnosis and prevention of cosmetic deformity. A case of LV over nose in a young male with ulceration is reported who responded well to anti-tubercular therapy, but left with scarring of nose, which could have been prevented if adequate awareness regarding extra-pulmonary cases would have been practiced.

No MeSH data available.


Related in: MedlinePlus