Limits...
Disseminated Kaposi's Sarcoma with the Involvement of Penis in the Setting of HIV Infection.

Farshidpour M, Marjani M, Baghaei P, Tabarsi P, Masjedi H, Asadi Kani ZF, Nadji SA, Mansouri D - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: It typically presents with several vascular nodules on the skin and other organs.The penile localization of KS, particularly on the shaft area, is exceptional.We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis.

View Article: PubMed Central - PubMed

Affiliation: Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT
Kaposi's sarcoma (KS) is a malignant proliferation of the endothelial cells. It typically presents with several vascular nodules on the skin and other organs. The penile localization of KS, particularly on the shaft area, is exceptional. We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis. Kaposi's sarcoma was diagnosed by histopathology.

No MeSH data available.


Related in: MedlinePlus

Penile lesion; Irregular vascular spaces, and spindle-shaped cells with extravasated RBCs (H and E, ×40)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4318030&req=5

Figure 2: Penile lesion; Irregular vascular spaces, and spindle-shaped cells with extravasated RBCs (H and E, ×40)

Mentions: Ultimately, skin biopsy of the lesions of foot and penis was performed for histopathologic examination. Hematoxylin and eosin-stained sections revealed a marked dermal neovascularization with spindle cells proliferation and also nuclear atypia compatible with Kaposi's sarcoma [Figure 2]. Moreover, nested polymerase chain reaction (PCR) for human herpes virus-8 (HHV8) was also positive in the penile tissue [Figure 3].


Disseminated Kaposi's Sarcoma with the Involvement of Penis in the Setting of HIV Infection.

Farshidpour M, Marjani M, Baghaei P, Tabarsi P, Masjedi H, Asadi Kani ZF, Nadji SA, Mansouri D - Indian J Dermatol (2015 Jan-Feb)

Penile lesion; Irregular vascular spaces, and spindle-shaped cells with extravasated RBCs (H and E, ×40)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318030&req=5

Figure 2: Penile lesion; Irregular vascular spaces, and spindle-shaped cells with extravasated RBCs (H and E, ×40)
Mentions: Ultimately, skin biopsy of the lesions of foot and penis was performed for histopathologic examination. Hematoxylin and eosin-stained sections revealed a marked dermal neovascularization with spindle cells proliferation and also nuclear atypia compatible with Kaposi's sarcoma [Figure 2]. Moreover, nested polymerase chain reaction (PCR) for human herpes virus-8 (HHV8) was also positive in the penile tissue [Figure 3].

Bottom Line: It typically presents with several vascular nodules on the skin and other organs.The penile localization of KS, particularly on the shaft area, is exceptional.We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis.

View Article: PubMed Central - PubMed

Affiliation: Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT
Kaposi's sarcoma (KS) is a malignant proliferation of the endothelial cells. It typically presents with several vascular nodules on the skin and other organs. The penile localization of KS, particularly on the shaft area, is exceptional. We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis. Kaposi's sarcoma was diagnosed by histopathology.

No MeSH data available.


Related in: MedlinePlus