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Disseminated Kaposi's Sarcoma with the Involvement of Penis in the Setting of HIV Infection.

Farshidpour M, Marjani M, Baghaei P, Tabarsi P, Masjedi H, Asadi Kani ZF, Nadji SA, Mansouri D - Indian J Dermatol (2015 Jan-Feb)

Bottom Line: It typically presents with several vascular nodules on the skin and other organs.The penile localization of KS, particularly on the shaft area, is exceptional.We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis.

View Article: PubMed Central - PubMed

Affiliation: Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT
Kaposi's sarcoma (KS) is a malignant proliferation of the endothelial cells. It typically presents with several vascular nodules on the skin and other organs. The penile localization of KS, particularly on the shaft area, is exceptional. We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis. Kaposi's sarcoma was diagnosed by histopathology.

No MeSH data available.


Related in: MedlinePlus

Violaceous macules localized on the glans and shaft of the penis
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Figure 1: Violaceous macules localized on the glans and shaft of the penis

Mentions: On admission to our hospital, he was toxic, dyspneic and febrile with oral temperature 40°C, respiratory rate 24 per/min, pulse rate 134 per/min, and blood pressure 110/60 mg/Hg. Peripheral blood leukocyte count was 4000/uL, hemoglobin 6 g/dl, platelet count 34000/uL, total bilirubin 15 mg/dl and direct 10 mg/dl, alanine aminotransferase 31 IU/L, aspartate aminotransferase 22 IU/L, and lactate dehydrogenase 512 IU/L. The patient was severely immunosuppressed with CD4 lymphocyte counts 79/mm3, plasma HIV viral load 395722 IU/ml, and HCV viral load was 21900 IU/ml. On physical examination, there were multiple purplish-black plaques on his arms and feet. Also, several small violaceous macules ranged from 2 mm to 1 cm were observed on the glans and shaft of the penis, which had started gradually over the last year [Figure 1].


Disseminated Kaposi's Sarcoma with the Involvement of Penis in the Setting of HIV Infection.

Farshidpour M, Marjani M, Baghaei P, Tabarsi P, Masjedi H, Asadi Kani ZF, Nadji SA, Mansouri D - Indian J Dermatol (2015 Jan-Feb)

Violaceous macules localized on the glans and shaft of the penis
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318030&req=5

Figure 1: Violaceous macules localized on the glans and shaft of the penis
Mentions: On admission to our hospital, he was toxic, dyspneic and febrile with oral temperature 40°C, respiratory rate 24 per/min, pulse rate 134 per/min, and blood pressure 110/60 mg/Hg. Peripheral blood leukocyte count was 4000/uL, hemoglobin 6 g/dl, platelet count 34000/uL, total bilirubin 15 mg/dl and direct 10 mg/dl, alanine aminotransferase 31 IU/L, aspartate aminotransferase 22 IU/L, and lactate dehydrogenase 512 IU/L. The patient was severely immunosuppressed with CD4 lymphocyte counts 79/mm3, plasma HIV viral load 395722 IU/ml, and HCV viral load was 21900 IU/ml. On physical examination, there were multiple purplish-black plaques on his arms and feet. Also, several small violaceous macules ranged from 2 mm to 1 cm were observed on the glans and shaft of the penis, which had started gradually over the last year [Figure 1].

Bottom Line: It typically presents with several vascular nodules on the skin and other organs.The penile localization of KS, particularly on the shaft area, is exceptional.We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis.

View Article: PubMed Central - PubMed

Affiliation: Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT
Kaposi's sarcoma (KS) is a malignant proliferation of the endothelial cells. It typically presents with several vascular nodules on the skin and other organs. The penile localization of KS, particularly on the shaft area, is exceptional. We report an HIV-positive 34-year-old man who had multiple purplish-black plaques on his extremities and several small violaceous macules on the glans and shaft of the penis. Kaposi's sarcoma was diagnosed by histopathology.

No MeSH data available.


Related in: MedlinePlus