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Prevalence of chronic kidney disease and associated factors in senegalese populations: a community-based study in saint-louis.

Seck SM, Doupa D, Gueye L, Dia CA - Nephrourol Mon (2014)

Bottom Line: Albuminuria > 1 g/L was found in 3.5% of patients.CKD was significantly more frequent among hypertensive patients in comparison with normotensive ones.Main associated factors are hypertension and age.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine and Nephrology, Faculty of Health Sciences, University Gaston Berger, Saint-Louis, Senegal.

ABSTRACT

Background: Chronic kidney disease (CKD) is an emerging worldwide epidemic but littledata concerning African populations are available.

Objectives: We aimed to assess prevalence of CKD in adult populations of Saint-Louis, northern Senegal.

Patients and methods: In a population-based survey between January and May 2012, we included 1037 adults ≥ 18 years of age who resided in Saint-Louis. Socio-demographic, clinical, and biologic data were collected during household visits. Serum creatinine was measured by Jaffé method. We estimated glomerular filtration rate (eGFR) using the four-variable Modification of Diet in Renal Disease (MDRD) equation and CKD was defined by eGFR< 60 mL/min/1.73 m(2) and/or albuminuria > 1 g/L. A multivariate logistic regression was performed to identify factors associated with CKD.

Results: The mean of participants' age was 47.9 ± 16.9 years (range, 18-87) and sex ratio (male to female) was 0.52. Majority of participants lived in urban areas (55.3%) and had school education (65.6%). Hypertension, diabetes, and obesity were present respectively in 39.1%, 12.7%, and 23.4% of participants. Overall CKD prevalence was 4.9% (95% CI, 3.5-6.2) with eGFR< 30 mL/min/1.73 m(2) in 0.9%. Albuminuria > 1 g/L was found in 3.5% of patients. CKD was significantly more frequent among hypertensive patients in comparison with normotensive ones. Risk factors associated with CKD were hypertension (12% of risk excess) and age (3% of risk excess).

Conclusions: CKD is frequent in adult population living in Northern Senegal. Main associated factors are hypertension and age. Prevention strategies are urgently needed to raise public awareness and promote early CKD detection and treatment in both urban and rural areas.

No MeSH data available.


Related in: MedlinePlus

Prevalence of Chronic Kidney Disease According to Age Groups
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fig12914: Prevalence of Chronic Kidney Disease According to Age Groups

Mentions: Overall adjusted prevalence of CKD in the total population was 6.1% (95% CI,4.7-7.6) with 3.5% presenting with albuminuria > 1 g/L. CKD prevalence was lower in women (5.7%) than in men (6.9%). A linear increase with age was found in CKD prevalence (P = 0.03). In the subgroup of people > 60 years of age, CKD was diagnosed in 14.3% (Figure 1). Surprisingly, people living in rural areas showed a similar prevalence of CKD stages ≥ 3 in comparison to those in urban areas (7.6% and 5.0%, respectively; P = 0.08); however, early stages of CKD (1 and 2) were more frequent in urban areas (Figure 2). Before the study, 83% of people with CKD in rural areas and 62.7% in urban areas were unaware of their disease.


Prevalence of chronic kidney disease and associated factors in senegalese populations: a community-based study in saint-louis.

Seck SM, Doupa D, Gueye L, Dia CA - Nephrourol Mon (2014)

Prevalence of Chronic Kidney Disease According to Age Groups
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4318016&req=5

fig12914: Prevalence of Chronic Kidney Disease According to Age Groups
Mentions: Overall adjusted prevalence of CKD in the total population was 6.1% (95% CI,4.7-7.6) with 3.5% presenting with albuminuria > 1 g/L. CKD prevalence was lower in women (5.7%) than in men (6.9%). A linear increase with age was found in CKD prevalence (P = 0.03). In the subgroup of people > 60 years of age, CKD was diagnosed in 14.3% (Figure 1). Surprisingly, people living in rural areas showed a similar prevalence of CKD stages ≥ 3 in comparison to those in urban areas (7.6% and 5.0%, respectively; P = 0.08); however, early stages of CKD (1 and 2) were more frequent in urban areas (Figure 2). Before the study, 83% of people with CKD in rural areas and 62.7% in urban areas were unaware of their disease.

Bottom Line: Albuminuria > 1 g/L was found in 3.5% of patients.CKD was significantly more frequent among hypertensive patients in comparison with normotensive ones.Main associated factors are hypertension and age.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine and Nephrology, Faculty of Health Sciences, University Gaston Berger, Saint-Louis, Senegal.

ABSTRACT

Background: Chronic kidney disease (CKD) is an emerging worldwide epidemic but littledata concerning African populations are available.

Objectives: We aimed to assess prevalence of CKD in adult populations of Saint-Louis, northern Senegal.

Patients and methods: In a population-based survey between January and May 2012, we included 1037 adults ≥ 18 years of age who resided in Saint-Louis. Socio-demographic, clinical, and biologic data were collected during household visits. Serum creatinine was measured by Jaffé method. We estimated glomerular filtration rate (eGFR) using the four-variable Modification of Diet in Renal Disease (MDRD) equation and CKD was defined by eGFR< 60 mL/min/1.73 m(2) and/or albuminuria > 1 g/L. A multivariate logistic regression was performed to identify factors associated with CKD.

Results: The mean of participants' age was 47.9 ± 16.9 years (range, 18-87) and sex ratio (male to female) was 0.52. Majority of participants lived in urban areas (55.3%) and had school education (65.6%). Hypertension, diabetes, and obesity were present respectively in 39.1%, 12.7%, and 23.4% of participants. Overall CKD prevalence was 4.9% (95% CI, 3.5-6.2) with eGFR< 30 mL/min/1.73 m(2) in 0.9%. Albuminuria > 1 g/L was found in 3.5% of patients. CKD was significantly more frequent among hypertensive patients in comparison with normotensive ones. Risk factors associated with CKD were hypertension (12% of risk excess) and age (3% of risk excess).

Conclusions: CKD is frequent in adult population living in Northern Senegal. Main associated factors are hypertension and age. Prevention strategies are urgently needed to raise public awareness and promote early CKD detection and treatment in both urban and rural areas.

No MeSH data available.


Related in: MedlinePlus