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Incidence and prediction of invasive disease and nodal metastasis in preoperatively diagnosed ductal carcinoma in situ.

Osako T, Iwase T, Ushijima M, Horii R, Fukami Y, Kimura K, Matsuura M, Akiyama F - Cancer Sci. (2014)

Bottom Line: Of the 113 patients with invasive disease, 4 (3.5%) and 9 (8.0%) had macro- and micrometastasis.Predictors of invasive disease included palpability, mammographic mass, and calcifications (spread >20 mm), and intraductal solid structure, but no predictor was found for SN metastasis.Therefore, even though occult invasive disease was found at final pathology, most of the patients had no metastasis or only micrometastasis in axillary nodes.

View Article: PubMed Central - PubMed

Affiliation: Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Pathology, The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.

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Correlation between pathological T status on final pathology and overall pathological N status in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ. is, in situ (intraductal carcinoma lesion); mi, micrometastasis.
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fig03: Correlation between pathological T status on final pathology and overall pathological N status in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ. is, in situ (intraductal carcinoma lesion); mi, micrometastasis.

Mentions: Of the 223 patients without invasive disease (pTis), 10 (4.5%) had nodal metastasis; 8 (3.6%) and 2 (0.9%) had pN1mi and pN1a/N2 disease, respectively (Fig.3). Of the 113 patients with detected invasive disease (pT1/T2), 13 (11.5%) had nodal metastasis; 9 (8.0%) and 4 (3.5%) had pN1mi and pN1a/N2 disease, respectively.


Incidence and prediction of invasive disease and nodal metastasis in preoperatively diagnosed ductal carcinoma in situ.

Osako T, Iwase T, Ushijima M, Horii R, Fukami Y, Kimura K, Matsuura M, Akiyama F - Cancer Sci. (2014)

Correlation between pathological T status on final pathology and overall pathological N status in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ. is, in situ (intraductal carcinoma lesion); mi, micrometastasis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4317837&req=5

fig03: Correlation between pathological T status on final pathology and overall pathological N status in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ. is, in situ (intraductal carcinoma lesion); mi, micrometastasis.
Mentions: Of the 223 patients without invasive disease (pTis), 10 (4.5%) had nodal metastasis; 8 (3.6%) and 2 (0.9%) had pN1mi and pN1a/N2 disease, respectively (Fig.3). Of the 113 patients with detected invasive disease (pT1/T2), 13 (11.5%) had nodal metastasis; 9 (8.0%) and 4 (3.5%) had pN1mi and pN1a/N2 disease, respectively.

Bottom Line: Of the 113 patients with invasive disease, 4 (3.5%) and 9 (8.0%) had macro- and micrometastasis.Predictors of invasive disease included palpability, mammographic mass, and calcifications (spread >20 mm), and intraductal solid structure, but no predictor was found for SN metastasis.Therefore, even though occult invasive disease was found at final pathology, most of the patients had no metastasis or only micrometastasis in axillary nodes.

View Article: PubMed Central - PubMed

Affiliation: Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Pathology, The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.

Show MeSH
Related in: MedlinePlus