Limits...
Incidence and prediction of invasive disease and nodal metastasis in preoperatively diagnosed ductal carcinoma in situ.

Osako T, Iwase T, Ushijima M, Horii R, Fukami Y, Kimura K, Matsuura M, Akiyama F - Cancer Sci. (2014)

Bottom Line: Of the 113 patients with invasive disease, 4 (3.5%) and 9 (8.0%) had macro- and micrometastasis.Predictors of invasive disease included palpability, mammographic mass, and calcifications (spread >20 mm), and intraductal solid structure, but no predictor was found for SN metastasis.Therefore, even though occult invasive disease was found at final pathology, most of the patients had no metastasis or only micrometastasis in axillary nodes.

View Article: PubMed Central - PubMed

Affiliation: Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Pathology, The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.

Show MeSH

Related in: MedlinePlus

Histological examinations of primary breast tumors in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ who underwent partial mastectomy (a) or total mastectomy (b).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4317837&req=5

fig01: Histological examinations of primary breast tumors in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ who underwent partial mastectomy (a) or total mastectomy (b).

Mentions: Partial mastectomy materials were sectioned continuously from the nipple side to the periphery at 5-mm intervals (Fig.1a). All sections were histologically examined with H&E staining. Total mastectomy materials were sectioned continuously from the nipple to the periphery at 5–7-mm intervals (Fig.1b). The sectioning was carried out to cover the entire tumor spread using macroscopic and radiologic findings as references. Most of the sections within the tumor spread were histologically confirmed with H&E staining.


Incidence and prediction of invasive disease and nodal metastasis in preoperatively diagnosed ductal carcinoma in situ.

Osako T, Iwase T, Ushijima M, Horii R, Fukami Y, Kimura K, Matsuura M, Akiyama F - Cancer Sci. (2014)

Histological examinations of primary breast tumors in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ who underwent partial mastectomy (a) or total mastectomy (b).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4317837&req=5

fig01: Histological examinations of primary breast tumors in patients with a preoperative needle-biopsy diagnosis of ductal carcinoma in situ who underwent partial mastectomy (a) or total mastectomy (b).
Mentions: Partial mastectomy materials were sectioned continuously from the nipple side to the periphery at 5-mm intervals (Fig.1a). All sections were histologically examined with H&E staining. Total mastectomy materials were sectioned continuously from the nipple to the periphery at 5–7-mm intervals (Fig.1b). The sectioning was carried out to cover the entire tumor spread using macroscopic and radiologic findings as references. Most of the sections within the tumor spread were histologically confirmed with H&E staining.

Bottom Line: Of the 113 patients with invasive disease, 4 (3.5%) and 9 (8.0%) had macro- and micrometastasis.Predictors of invasive disease included palpability, mammographic mass, and calcifications (spread >20 mm), and intraductal solid structure, but no predictor was found for SN metastasis.Therefore, even though occult invasive disease was found at final pathology, most of the patients had no metastasis or only micrometastasis in axillary nodes.

View Article: PubMed Central - PubMed

Affiliation: Division of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, Tokyo, Japan; Department of Pathology, The Cancer Institute Hospital of the Japanese Foundation for Cancer Research, Tokyo, Japan.

Show MeSH
Related in: MedlinePlus