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Renal failure caused by malakoplakia lesions of the urinary bladder.

Stamatiou K, Chelioti E, Tsavari A, Koulia K, Papalexandrou A, Efthymiou E, Tsilivigkou M, Vasilakaki T - Nephrourol Mon (2014)

Bottom Line: Μalakoplakia is a rare inflammatory condition of the urogenital tract.The most frequently affected organ is urinary bladder.In this study, we presented a case of urinary bladder malakoplakia associated with advanced obstructive uropathy and renal failure.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, "Tzaneion" General Hospital of Piraeus, Athens, Greece.

ABSTRACT
╬ťalakoplakia is a rare inflammatory condition of the urogenital tract. The most frequently affected organ is urinary bladder. This condition has features of a granulomatous inflammation, the pathogenesis of which is not well understood. In this study, we presented a case of urinary bladder malakoplakia associated with advanced obstructive uropathy and renal failure.

No MeSH data available.


Related in: MedlinePlus

Transabdominal Ultrasound: Abnormal Thickening of Luminal Bladder, With Presence of Nodules.
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fig12090: Transabdominal Ultrasound: Abnormal Thickening of Luminal Bladder, With Presence of Nodules.

Mentions: A 72-year-old Caucasian man was admitted to the emergency department with reported inability to urinate and fever. He also reported weakness, exhaustion, and irritative voiding symptoms for approximately one month. His current medical history included diabetes, vascular disease, and recurrent urinary tract infections (UTI). In addition, he underwent bladder biopsy due to abnormal formation of bladder mucosa (diagnosed as nonspecific inflammation) and transurethral prostatectomy, three years prior to the admission. Besides hypotension, other vital signs were normal. Upon investigation, he was diagnosed with obstructive uropathy with bilateral hydronephrosis, concomitant renal insufficiency, (serum creatinine: 21 mg/dL) and anemia (hematocrit: 19%). The serum glucose level was 300 mg/dL and there was no leukocytosis. Urinalysis revealed hematuria, pyuria, and bacteriuria. Ultrasound scan of the abdomen showed abnormal thickening of the bladder wall with presence of nodules and small functional capacity, while no residual urine was found (Figure 1). On clinical examination, the prostate gland was smooth and small. The patient underwent dialysis sessions (due to the underlying hyperkalemia and anuria) and nephrostomy tubes were placed in both sides. After stabilization of renal function the patient underwent cystoscopy, which revealed atypical polypoid mucosal lesions of the bladder. They resembled neoplastic masses and scattered red-yellow nodules of 2-3 and 5 cm, located mainly in the trigonal area, left ureteric orifice, posterior wall, and bladder roof.


Renal failure caused by malakoplakia lesions of the urinary bladder.

Stamatiou K, Chelioti E, Tsavari A, Koulia K, Papalexandrou A, Efthymiou E, Tsilivigkou M, Vasilakaki T - Nephrourol Mon (2014)

Transabdominal Ultrasound: Abnormal Thickening of Luminal Bladder, With Presence of Nodules.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4317724&req=5

fig12090: Transabdominal Ultrasound: Abnormal Thickening of Luminal Bladder, With Presence of Nodules.
Mentions: A 72-year-old Caucasian man was admitted to the emergency department with reported inability to urinate and fever. He also reported weakness, exhaustion, and irritative voiding symptoms for approximately one month. His current medical history included diabetes, vascular disease, and recurrent urinary tract infections (UTI). In addition, he underwent bladder biopsy due to abnormal formation of bladder mucosa (diagnosed as nonspecific inflammation) and transurethral prostatectomy, three years prior to the admission. Besides hypotension, other vital signs were normal. Upon investigation, he was diagnosed with obstructive uropathy with bilateral hydronephrosis, concomitant renal insufficiency, (serum creatinine: 21 mg/dL) and anemia (hematocrit: 19%). The serum glucose level was 300 mg/dL and there was no leukocytosis. Urinalysis revealed hematuria, pyuria, and bacteriuria. Ultrasound scan of the abdomen showed abnormal thickening of the bladder wall with presence of nodules and small functional capacity, while no residual urine was found (Figure 1). On clinical examination, the prostate gland was smooth and small. The patient underwent dialysis sessions (due to the underlying hyperkalemia and anuria) and nephrostomy tubes were placed in both sides. After stabilization of renal function the patient underwent cystoscopy, which revealed atypical polypoid mucosal lesions of the bladder. They resembled neoplastic masses and scattered red-yellow nodules of 2-3 and 5 cm, located mainly in the trigonal area, left ureteric orifice, posterior wall, and bladder roof.

Bottom Line: Μalakoplakia is a rare inflammatory condition of the urogenital tract.The most frequently affected organ is urinary bladder.In this study, we presented a case of urinary bladder malakoplakia associated with advanced obstructive uropathy and renal failure.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, "Tzaneion" General Hospital of Piraeus, Athens, Greece.

ABSTRACT
╬ťalakoplakia is a rare inflammatory condition of the urogenital tract. The most frequently affected organ is urinary bladder. This condition has features of a granulomatous inflammation, the pathogenesis of which is not well understood. In this study, we presented a case of urinary bladder malakoplakia associated with advanced obstructive uropathy and renal failure.

No MeSH data available.


Related in: MedlinePlus