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The Western Denmark Cardiac Computed Tomography Registry: a review and validation study.

Nielsen LH, Nørgaard BL, Tilsted HH, Sand NP, Jensen JM, Bøttcher M, Diederichsen AC, Lambrechtsen J, Kristensen LD, Mickley H, Munkholm H, Gøtzsche O, Knudsen LL, Bøtker HE, Pedersen L, Schmidt M - Clin Epidemiol (2014)

Bottom Line: Stratification by center status showed consistently high positive and negative predictive values for both university (96%/99%) and nonuniversity centers (97%/99%).WDHR-CCTR provides ongoing prospective registration of all cardiac CTs performed in Western Denmark since 2008.Overall, the registry data have a high degree of completeness and validity, making it a valuable tool for clinical epidemiological research.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Lillbaelt Hospital-Vejle, Vejle, Denmark.

ABSTRACT

Background: As a subregistry to the Western Denmark Heart Registry (WDHR), the Western Denmark Cardiac Computed Tomography Registry (WDHR-CCTR) is a clinical database established in 2008 to monitor and improve the quality of cardiac computed tomography (CT) in Western Denmark.

Objective: We examined the content, data quality, and research potential of the WDHR-CCTR.

Methods: We retrieved 2008-2012 data to examine the 1) content; 2) completeness of procedure registration using the Danish National Patient Registry as reference; 3) completeness of variable registration comparing observed vs expected numbers; and 4) positive predictive values as well as negative predictive values of 19 main patient and procedure variables.

Results: By December 31, 2012, almost 22,000 cardiac CTs with up to 40 variables for each procedure have been registered. Of these, 87% were coronary CT angiography performed in patients with symptoms indicative of coronary artery disease. Compared with the Danish National Patient Registry, the overall procedure completeness was 72%. However, an additional medical record review of 282 patients registered in the Danish National Patient Registry, but not in the WDHR-CCTR, showed that coronary CT angiographies accounted for only 23% of all nonregistered cardiac CTs, indicating >90% completeness of coronary CT angiographies in the WDHR-CCTR. The completeness of individual variables varied substantially (range: 0%-100%), but was >85% for more than 70% of all variables. Using medical record review of 250 randomly selected patients as reference standard, the positive predictive value for the 19 variables ranged from 89% to 100% (overall 97%), whereas the negative predictive value ranged from 97% to 100% (overall 99%). Stratification by center status showed consistently high positive and negative predictive values for both university (96%/99%) and nonuniversity centers (97%/99%).

Conclusion: WDHR-CCTR provides ongoing prospective registration of all cardiac CTs performed in Western Denmark since 2008. Overall, the registry data have a high degree of completeness and validity, making it a valuable tool for clinical epidemiological research.

No MeSH data available.


Related in: MedlinePlus

Cardiac centers reporting to Western Denmark Cardiac Computed Tomography Registry.Notes: Color codings indicate the five regions of Denmark. Numbers indicate the cardiac centers reporting to the registry: (1) Vendsyssel Hospital; (2) Aalborg University Hospital; (3) Regional Hospital Herning; (4) Regional Hospital Silkeborg; (5) Aarhus University Hospital (previously comprising two separate cardiac centers); (6) Lillebaelt Hospital-Vejle; (7) Hospital of Southwestern Denmark-Esbjerg; (8) Odense University Hospital; and (9) Odense University Hospital-Svendborg Hospital.
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f1-clep-7-053: Cardiac centers reporting to Western Denmark Cardiac Computed Tomography Registry.Notes: Color codings indicate the five regions of Denmark. Numbers indicate the cardiac centers reporting to the registry: (1) Vendsyssel Hospital; (2) Aalborg University Hospital; (3) Regional Hospital Herning; (4) Regional Hospital Silkeborg; (5) Aarhus University Hospital (previously comprising two separate cardiac centers); (6) Lillebaelt Hospital-Vejle; (7) Hospital of Southwestern Denmark-Esbjerg; (8) Odense University Hospital; and (9) Odense University Hospital-Svendborg Hospital.

Mentions: As of 2014, all nine cardiac centers (three university and six nonuniversity centers) in Western Denmark report to the WDHR-CCTR (Figure 1). University cardiac centers are defined by performing coronary revascularization procedures. WDHR-CCTR previously included ten cardiac centers, but recently the two centers at Aarhus University Hospital (Skejby and Tage Hansens Gade) were merged into one center. The WDHR-CCTR includes information on adult patients (≥16 years) referred for cardiac CT in Western Denmark. We included all patients registered between January 1, 2008, and December 31, 2012. In addition, we examined separately the subgroup of patients undergoing coronary CTA on suspicion of angina.


The Western Denmark Cardiac Computed Tomography Registry: a review and validation study.

Nielsen LH, Nørgaard BL, Tilsted HH, Sand NP, Jensen JM, Bøttcher M, Diederichsen AC, Lambrechtsen J, Kristensen LD, Mickley H, Munkholm H, Gøtzsche O, Knudsen LL, Bøtker HE, Pedersen L, Schmidt M - Clin Epidemiol (2014)

Cardiac centers reporting to Western Denmark Cardiac Computed Tomography Registry.Notes: Color codings indicate the five regions of Denmark. Numbers indicate the cardiac centers reporting to the registry: (1) Vendsyssel Hospital; (2) Aalborg University Hospital; (3) Regional Hospital Herning; (4) Regional Hospital Silkeborg; (5) Aarhus University Hospital (previously comprising two separate cardiac centers); (6) Lillebaelt Hospital-Vejle; (7) Hospital of Southwestern Denmark-Esbjerg; (8) Odense University Hospital; and (9) Odense University Hospital-Svendborg Hospital.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4317160&req=5

f1-clep-7-053: Cardiac centers reporting to Western Denmark Cardiac Computed Tomography Registry.Notes: Color codings indicate the five regions of Denmark. Numbers indicate the cardiac centers reporting to the registry: (1) Vendsyssel Hospital; (2) Aalborg University Hospital; (3) Regional Hospital Herning; (4) Regional Hospital Silkeborg; (5) Aarhus University Hospital (previously comprising two separate cardiac centers); (6) Lillebaelt Hospital-Vejle; (7) Hospital of Southwestern Denmark-Esbjerg; (8) Odense University Hospital; and (9) Odense University Hospital-Svendborg Hospital.
Mentions: As of 2014, all nine cardiac centers (three university and six nonuniversity centers) in Western Denmark report to the WDHR-CCTR (Figure 1). University cardiac centers are defined by performing coronary revascularization procedures. WDHR-CCTR previously included ten cardiac centers, but recently the two centers at Aarhus University Hospital (Skejby and Tage Hansens Gade) were merged into one center. The WDHR-CCTR includes information on adult patients (≥16 years) referred for cardiac CT in Western Denmark. We included all patients registered between January 1, 2008, and December 31, 2012. In addition, we examined separately the subgroup of patients undergoing coronary CTA on suspicion of angina.

Bottom Line: Stratification by center status showed consistently high positive and negative predictive values for both university (96%/99%) and nonuniversity centers (97%/99%).WDHR-CCTR provides ongoing prospective registration of all cardiac CTs performed in Western Denmark since 2008.Overall, the registry data have a high degree of completeness and validity, making it a valuable tool for clinical epidemiological research.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Lillbaelt Hospital-Vejle, Vejle, Denmark.

ABSTRACT

Background: As a subregistry to the Western Denmark Heart Registry (WDHR), the Western Denmark Cardiac Computed Tomography Registry (WDHR-CCTR) is a clinical database established in 2008 to monitor and improve the quality of cardiac computed tomography (CT) in Western Denmark.

Objective: We examined the content, data quality, and research potential of the WDHR-CCTR.

Methods: We retrieved 2008-2012 data to examine the 1) content; 2) completeness of procedure registration using the Danish National Patient Registry as reference; 3) completeness of variable registration comparing observed vs expected numbers; and 4) positive predictive values as well as negative predictive values of 19 main patient and procedure variables.

Results: By December 31, 2012, almost 22,000 cardiac CTs with up to 40 variables for each procedure have been registered. Of these, 87% were coronary CT angiography performed in patients with symptoms indicative of coronary artery disease. Compared with the Danish National Patient Registry, the overall procedure completeness was 72%. However, an additional medical record review of 282 patients registered in the Danish National Patient Registry, but not in the WDHR-CCTR, showed that coronary CT angiographies accounted for only 23% of all nonregistered cardiac CTs, indicating >90% completeness of coronary CT angiographies in the WDHR-CCTR. The completeness of individual variables varied substantially (range: 0%-100%), but was >85% for more than 70% of all variables. Using medical record review of 250 randomly selected patients as reference standard, the positive predictive value for the 19 variables ranged from 89% to 100% (overall 97%), whereas the negative predictive value ranged from 97% to 100% (overall 99%). Stratification by center status showed consistently high positive and negative predictive values for both university (96%/99%) and nonuniversity centers (97%/99%).

Conclusion: WDHR-CCTR provides ongoing prospective registration of all cardiac CTs performed in Western Denmark since 2008. Overall, the registry data have a high degree of completeness and validity, making it a valuable tool for clinical epidemiological research.

No MeSH data available.


Related in: MedlinePlus