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A history of diabetes but not hyperglycaemia during exacerbation of obstructive lung disease has impact on long-term mortality: a prospective, observational cohort study.

Koskela HO, Salonen PH, Romppanen J, Niskanen L - BMJ Open (2015)

Bottom Line: Several possible confounders were also recorded.Within the patients without diabetes, neither fasting (aHR 0.92 (0.42 to 2.02)) nor postprandial ((aHR 1.04 (0.50 to 2.12)) hyperglycaemia was associated with late mortality.There were no statistically significant differences in the underlying causes of death between the patients with and without diabetes.

View Article: PubMed Central - PubMed

Affiliation: Pulmonary Division, Unit for Medicine and Clinical Research, Kuopio University Hospital, Kuopio, Finland Faculty of Health Sciences, School of Medicine, Institute of Clinical Sciences, University of Eastern Finland, Kuopio, Finland.

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Inclusion of patients (COPD, chronic obstructive pulmonary disease).
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BMJOPEN2014006794F1: Inclusion of patients (COPD, chronic obstructive pulmonary disease).

Mentions: This prospective, observational cohort study was carried out at Kuopio University Hospital in Finland. From November 2006 to May 2008 all adult patients admitted to the pulmonology ward due to acute exacerbation of asthma or COPD were recruited. Patients were not included if they had severe disease requiring treatment in the intensive or intermediate care unit. During that time, 186 patients were admitted (figure 1). Of them, 32 were excluded: 13 patients could not give their informed consent due to confusion, 10 patients were missed due to technical reasons, 6 refused to participate and 3 patients were missed due to diverse reasons. One of the 154 included patients died within 30 days after admission (early death) and was not included in the analysis. At discharge, the attending physician was asked whether the patient suffered mainly from asthma or COPD. Among the 153 patients in the final analysis, 110 (72%) suffered from probable asthma and 43 (28%) from probable COPD. The proportion of ever-smokers was 49% among the patients with asthma and 95% among the patients with COPD. The baseline results have been published before.1 All patients gave their written informed consent.


A history of diabetes but not hyperglycaemia during exacerbation of obstructive lung disease has impact on long-term mortality: a prospective, observational cohort study.

Koskela HO, Salonen PH, Romppanen J, Niskanen L - BMJ Open (2015)

Inclusion of patients (COPD, chronic obstructive pulmonary disease).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4316436&req=5

BMJOPEN2014006794F1: Inclusion of patients (COPD, chronic obstructive pulmonary disease).
Mentions: This prospective, observational cohort study was carried out at Kuopio University Hospital in Finland. From November 2006 to May 2008 all adult patients admitted to the pulmonology ward due to acute exacerbation of asthma or COPD were recruited. Patients were not included if they had severe disease requiring treatment in the intensive or intermediate care unit. During that time, 186 patients were admitted (figure 1). Of them, 32 were excluded: 13 patients could not give their informed consent due to confusion, 10 patients were missed due to technical reasons, 6 refused to participate and 3 patients were missed due to diverse reasons. One of the 154 included patients died within 30 days after admission (early death) and was not included in the analysis. At discharge, the attending physician was asked whether the patient suffered mainly from asthma or COPD. Among the 153 patients in the final analysis, 110 (72%) suffered from probable asthma and 43 (28%) from probable COPD. The proportion of ever-smokers was 49% among the patients with asthma and 95% among the patients with COPD. The baseline results have been published before.1 All patients gave their written informed consent.

Bottom Line: Several possible confounders were also recorded.Within the patients without diabetes, neither fasting (aHR 0.92 (0.42 to 2.02)) nor postprandial ((aHR 1.04 (0.50 to 2.12)) hyperglycaemia was associated with late mortality.There were no statistically significant differences in the underlying causes of death between the patients with and without diabetes.

View Article: PubMed Central - PubMed

Affiliation: Pulmonary Division, Unit for Medicine and Clinical Research, Kuopio University Hospital, Kuopio, Finland Faculty of Health Sciences, School of Medicine, Institute of Clinical Sciences, University of Eastern Finland, Kuopio, Finland.

Show MeSH
Related in: MedlinePlus