Wallerian degeneration and recovery of motor nerves after multiple focused cold therapies.
Bottom Line: We evaluated the effects of single and 3 repeat treatments with a cryoprobe device (-55°C) on a sciatic nerve rat model.Long-term effects of repeated treatment were evaluated through assessments of physiological function and histological analysis.Progressive axonal regeneration was followed by normal recovery by 24 weeks post-treatment.
Affiliation: Myoscience, Inc., Redwood City, California, 94063, USA.Show MeSH
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Mentions: Overlay of the repeated treatments shows similar weakening and recovery patterns of toe function and motor function (Fig. 5). Consistent patterns were observed with each successive treatment.
Affiliation: Myoscience, Inc., Redwood City, California, 94063, USA.