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Indolent metastatic squamous cell carcinoma of unknown primary in the intrathoracic lymph node: a case report and review of the literatures.

Kim MJ, Lim SH, Han SJ, Choi KH, Lee SH, Park MW, Kang H, Na JO - Tuberc Respir Dis (Seoul) (2015)

Bottom Line: Abnormal mass in the right hilar area was incidentally detected.A chest computed tomography scan showed a 2.5-cm diameter mass in the right hilum that had changed little in size for 3 years.The patient received adjuvant chemotherapy for a diagnosis of T0N1M0 lung cancer.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.

ABSTRACT
Metastatic squamous cell carcinoma from a cancer of unknown primary (CUP) affecting the intrathoracic lymph node is very rare. We reported a case of metastatic squamous cell carcinoma in the hilar and interlobar lymph node from a patient with CUP and reviewed the associated literature. Abnormal mass in the right hilar area was incidentally detected. A chest computed tomography scan showed a 2.5-cm diameter mass in the right hilum that had changed little in size for 3 years. The patient underwent a right pneumonectomy and mediastinal lymph node dissection. A metastatic squamous cell carcinoma in the hilar and interlobar lymph nodes without a primary lung or other lesion was diagnosed. The patient received adjuvant chemotherapy for a diagnosis of T0N1M0 lung cancer.

No MeSH data available.


Related in: MedlinePlus

Chest computed tomography (CT) scan in December of 2012 (B) showed a 2.5-cm diameter hilar mass that was little changed, as compared to the cardiac angio CT scan in March of 2010 (A).
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Figure 1: Chest computed tomography (CT) scan in December of 2012 (B) showed a 2.5-cm diameter hilar mass that was little changed, as compared to the cardiac angio CT scan in March of 2010 (A).

Mentions: The patient has hypertension, diabetes mellitus and a history of angina. He visited the division of cardiology of our hospital in March of 2010, and was diagnosed with angina and hypertension. A cardiac angio computed tomography (CT) scan performed at that time detected a 2.5-cm diameter, minimally enhanced mass in the right hilar area (Figure 1A). Since then, he failed to return and was lost to follow up. The patient had a 40 pack-year cigarette smoking history and a family history of stomach cancer. On this admission, the physical examination was unremarkable. The blood examination showed eosinophilia (eosinophil 18.5%, 1,750/µL) and the rest of the laboratory tests including serum tumor markers (carcinoembryonic antigen, cancer antigen 19-9, alpha-fetoprotein, and prostate specific antigen), viral markers (hepatitis virus and human immunodeficiency virus), and autoimmune antibody titers were all within normal range. Examination for parasites was also negative.


Indolent metastatic squamous cell carcinoma of unknown primary in the intrathoracic lymph node: a case report and review of the literatures.

Kim MJ, Lim SH, Han SJ, Choi KH, Lee SH, Park MW, Kang H, Na JO - Tuberc Respir Dis (Seoul) (2015)

Chest computed tomography (CT) scan in December of 2012 (B) showed a 2.5-cm diameter hilar mass that was little changed, as compared to the cardiac angio CT scan in March of 2010 (A).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4311031&req=5

Figure 1: Chest computed tomography (CT) scan in December of 2012 (B) showed a 2.5-cm diameter hilar mass that was little changed, as compared to the cardiac angio CT scan in March of 2010 (A).
Mentions: The patient has hypertension, diabetes mellitus and a history of angina. He visited the division of cardiology of our hospital in March of 2010, and was diagnosed with angina and hypertension. A cardiac angio computed tomography (CT) scan performed at that time detected a 2.5-cm diameter, minimally enhanced mass in the right hilar area (Figure 1A). Since then, he failed to return and was lost to follow up. The patient had a 40 pack-year cigarette smoking history and a family history of stomach cancer. On this admission, the physical examination was unremarkable. The blood examination showed eosinophilia (eosinophil 18.5%, 1,750/µL) and the rest of the laboratory tests including serum tumor markers (carcinoembryonic antigen, cancer antigen 19-9, alpha-fetoprotein, and prostate specific antigen), viral markers (hepatitis virus and human immunodeficiency virus), and autoimmune antibody titers were all within normal range. Examination for parasites was also negative.

Bottom Line: Abnormal mass in the right hilar area was incidentally detected.A chest computed tomography scan showed a 2.5-cm diameter mass in the right hilum that had changed little in size for 3 years.The patient received adjuvant chemotherapy for a diagnosis of T0N1M0 lung cancer.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.

ABSTRACT
Metastatic squamous cell carcinoma from a cancer of unknown primary (CUP) affecting the intrathoracic lymph node is very rare. We reported a case of metastatic squamous cell carcinoma in the hilar and interlobar lymph node from a patient with CUP and reviewed the associated literature. Abnormal mass in the right hilar area was incidentally detected. A chest computed tomography scan showed a 2.5-cm diameter mass in the right hilum that had changed little in size for 3 years. The patient underwent a right pneumonectomy and mediastinal lymph node dissection. A metastatic squamous cell carcinoma in the hilar and interlobar lymph nodes without a primary lung or other lesion was diagnosed. The patient received adjuvant chemotherapy for a diagnosis of T0N1M0 lung cancer.

No MeSH data available.


Related in: MedlinePlus