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Chronic renal failure presenting for the first time as pulmonary mucormycosis with a fatal outcome.

Jayakrishnan B, Al Aghbari J, Rizavi D, Srinivasan S, Lakhtakia R, Al Riyami D - Case Rep Nephrol (2015)

Bottom Line: Renal failure as the predominant presenting feature is not common in mucormycosis.Moreover, sudden, massive hemoptysis is not a usual complication.In this report we describe fatal pulmonary mucormycosis in a young patient with a previously undiagnosed chronic renal failure.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Sultan Qaboos University Hospital, 123 Muscat, Oman.

ABSTRACT
Pulmonary mucormycosis is an uncommon, but important, opportunistic fungal pneumonia which is often diagnosed late. Renal failure as the predominant presenting feature is not common in mucormycosis. Moreover, sudden, massive hemoptysis is not a usual complication. In this report we describe fatal pulmonary mucormycosis in a young patient with a previously undiagnosed chronic renal failure.

No MeSH data available.


Related in: MedlinePlus

Chest radiograph showing a right mid zone consolidation and a slightly blunt right costophrenic angle.
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fig1: Chest radiograph showing a right mid zone consolidation and a slightly blunt right costophrenic angle.

Mentions: On arrival he was in severe distress with a respiratory rate of 44/minute, heart rate of 103/minute, and blood pressure of 148/97 mmHg. Arterial blood gas analysis while on oxygen showed severe metabolic acidosis {pH—6.9, PCO2—12 mmHg, PO2—600 mmHg, and HCO3—4.4 mmol/L}. Creatinine and urea were very high and the hemoglobin was very low. The basic blood test results were as follows: fasting blood sugar—4.9 mmol/L; creatinine—1327 μmol/L; urea—46.8 mmol/L; bicarbonate—2 mmol/L; sodium—119 mmol/L; potassium—5.8 mmol/L; glomerular filtration rate—4 mL/min/1.73 m2; anion gap—22 mmol/L; calcium—2.18 mmol/L; phosphate—3.98 mmol/L; lactate—0.7 mmol/L; hemoglobin—5.4 g/dL; white cell count—52 × 109/L; lactate dehydrogenase—378 U/L; creatine kinase—2548 U/L; INR—1.29; activated partial thromboplastin time—69.2 seconds. Urine dipstick showed the presence of proteins, glucose, and red blood cells. Chest radiograph showed consolidation in the right mid zone and slight blunting of the right costophrenic angle (Figure 1).


Chronic renal failure presenting for the first time as pulmonary mucormycosis with a fatal outcome.

Jayakrishnan B, Al Aghbari J, Rizavi D, Srinivasan S, Lakhtakia R, Al Riyami D - Case Rep Nephrol (2015)

Chest radiograph showing a right mid zone consolidation and a slightly blunt right costophrenic angle.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4309303&req=5

fig1: Chest radiograph showing a right mid zone consolidation and a slightly blunt right costophrenic angle.
Mentions: On arrival he was in severe distress with a respiratory rate of 44/minute, heart rate of 103/minute, and blood pressure of 148/97 mmHg. Arterial blood gas analysis while on oxygen showed severe metabolic acidosis {pH—6.9, PCO2—12 mmHg, PO2—600 mmHg, and HCO3—4.4 mmol/L}. Creatinine and urea were very high and the hemoglobin was very low. The basic blood test results were as follows: fasting blood sugar—4.9 mmol/L; creatinine—1327 μmol/L; urea—46.8 mmol/L; bicarbonate—2 mmol/L; sodium—119 mmol/L; potassium—5.8 mmol/L; glomerular filtration rate—4 mL/min/1.73 m2; anion gap—22 mmol/L; calcium—2.18 mmol/L; phosphate—3.98 mmol/L; lactate—0.7 mmol/L; hemoglobin—5.4 g/dL; white cell count—52 × 109/L; lactate dehydrogenase—378 U/L; creatine kinase—2548 U/L; INR—1.29; activated partial thromboplastin time—69.2 seconds. Urine dipstick showed the presence of proteins, glucose, and red blood cells. Chest radiograph showed consolidation in the right mid zone and slight blunting of the right costophrenic angle (Figure 1).

Bottom Line: Renal failure as the predominant presenting feature is not common in mucormycosis.Moreover, sudden, massive hemoptysis is not a usual complication.In this report we describe fatal pulmonary mucormycosis in a young patient with a previously undiagnosed chronic renal failure.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Sultan Qaboos University Hospital, 123 Muscat, Oman.

ABSTRACT
Pulmonary mucormycosis is an uncommon, but important, opportunistic fungal pneumonia which is often diagnosed late. Renal failure as the predominant presenting feature is not common in mucormycosis. Moreover, sudden, massive hemoptysis is not a usual complication. In this report we describe fatal pulmonary mucormycosis in a young patient with a previously undiagnosed chronic renal failure.

No MeSH data available.


Related in: MedlinePlus