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Preoperative functional MRI localization of language areas in Chinese patients with brain tumors: Validation with intraoperative electrocortical mapping.

Xia H, Huang W, Wu L, Ma H, Wang X, Chen X, Sun S, Jia X - Neural Regen Res (2012)

Bottom Line: Preoperative functional MRI was performed to locate Broca's or Wernicke's area, and the cortex that was essential for language function was determined by electrocortical mapping.Results showed that the sensitivity and specificity of preoperative functional MRI were 80.0% and 85.0% in Broca's area and 66.6% and 85.2% in Wernicke's area, respectively.These experimental findings indicate that functional MRI is an accurate, reliable technique with which to identify the location of Wernicke's area or Broca's area in patients with brain tumors.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.

ABSTRACT
Ten Chinese patients with brain tumors involving language regions were selected. Preoperative functional MRI was performed to locate Broca's or Wernicke's area, and the cortex that was essential for language function was determined by electrocortical mapping. A site-by-site comparison between functional MRI and electrocortical mapping was performed with the aid of a neuronavigation device. Results showed that the sensitivity and specificity of preoperative functional MRI were 80.0% and 85.0% in Broca's area and 66.6% and 85.2% in Wernicke's area, respectively. These experimental findings indicate that functional MRI is an accurate, reliable technique with which to identify the location of Wernicke's area or Broca's area in patients with brain tumors.

No MeSH data available.


Related in: MedlinePlus

Intraoperative electrocortical mapping under awake craniotomy for localization of Broca's area.
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Figure 2: Intraoperative electrocortical mapping under awake craniotomy for localization of Broca's area.

Mentions: Intraoperative ECM under awake craniotomy is still the “gold standard” of localization of language areas. The results are listed in Figure 2 and supplementary Figure 2 online. Functional MRI was employed to determine the true-positive, true-negative, false-positive, and false- negative in localization of Wernicke's area and Broca's area (Table 2).


Preoperative functional MRI localization of language areas in Chinese patients with brain tumors: Validation with intraoperative electrocortical mapping.

Xia H, Huang W, Wu L, Ma H, Wang X, Chen X, Sun S, Jia X - Neural Regen Res (2012)

Intraoperative electrocortical mapping under awake craniotomy for localization of Broca's area.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4308752&req=5

Figure 2: Intraoperative electrocortical mapping under awake craniotomy for localization of Broca's area.
Mentions: Intraoperative ECM under awake craniotomy is still the “gold standard” of localization of language areas. The results are listed in Figure 2 and supplementary Figure 2 online. Functional MRI was employed to determine the true-positive, true-negative, false-positive, and false- negative in localization of Wernicke's area and Broca's area (Table 2).

Bottom Line: Preoperative functional MRI was performed to locate Broca's or Wernicke's area, and the cortex that was essential for language function was determined by electrocortical mapping.Results showed that the sensitivity and specificity of preoperative functional MRI were 80.0% and 85.0% in Broca's area and 66.6% and 85.2% in Wernicke's area, respectively.These experimental findings indicate that functional MRI is an accurate, reliable technique with which to identify the location of Wernicke's area or Broca's area in patients with brain tumors.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.

ABSTRACT
Ten Chinese patients with brain tumors involving language regions were selected. Preoperative functional MRI was performed to locate Broca's or Wernicke's area, and the cortex that was essential for language function was determined by electrocortical mapping. A site-by-site comparison between functional MRI and electrocortical mapping was performed with the aid of a neuronavigation device. Results showed that the sensitivity and specificity of preoperative functional MRI were 80.0% and 85.0% in Broca's area and 66.6% and 85.2% in Wernicke's area, respectively. These experimental findings indicate that functional MRI is an accurate, reliable technique with which to identify the location of Wernicke's area or Broca's area in patients with brain tumors.

No MeSH data available.


Related in: MedlinePlus