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Kidney stone analysis: "Give me your stone, I will tell you who you are!".

Cloutier J, Villa L, Traxer O, Daudon M - World J Urol (2014)

Bottom Line: Stone analysis is an important part in the evaluation of patients having stone disease.Unfortunately, chemical methods often are inadequate to analyze accurately urinary calculi and could fail to detect some elements into the stone.Here, specific chemical types with their different crystalline phases are shown in connection with their different etiologies involved.

View Article: PubMed Central - PubMed

Affiliation: Urology Department, Tenon University Hospital, 4 rue de la Chine, 75970, Paris Cedex 20, France.

ABSTRACT

Introduction: Stone analysis is an important part in the evaluation of patients having stone disease. This could orientate the physician toward particular etiologies.

Material and methods: Chemical and physical methods are both used for analysis. Unfortunately, chemical methods often are inadequate to analyze accurately urinary calculi and could fail to detect some elements into the stone. Physical methods, in counterpart, are becoming more and more used in high-volume laboratories. The present manuscript will provide a review on analytic methods, and review all the information that should be included into an appropriate morpho-constitutional analysis.

Conclusion: This report can supply an excellent summarization of the stone morphology and give the opportunity to find specific metabolic disorders and different lithogenic process into the same stone. Here, specific chemical types with their different crystalline phases are shown in connection with their different etiologies involved.

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Related in: MedlinePlus

Calcium phosphate stones mainly composed of carbapatite: a subtype IVa1 (surface); b subtype IVa1 (section); c subtype IVa2 (surface): note the glazed aspect and the presence of very tiny cracks; d subtype IVa2 (section); e subtype IVb (surface); f subtype IVb (section)
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Fig8: Calcium phosphate stones mainly composed of carbapatite: a subtype IVa1 (surface); b subtype IVa1 (section); c subtype IVa2 (surface): note the glazed aspect and the presence of very tiny cracks; d subtype IVa2 (section); e subtype IVb (surface); f subtype IVb (section)

Mentions: An infrequent cause of CaPh stones is a kidney cells impairment to excrete protons as observed in inherited distal acidification defect or acquired auto-immune diseases such as Sjogren’s syndrome. In such metabolic diseases, urinary calculi are mainly composed of carbapatite with a very high content of CaPh, often above 80 % of the stone mass. While most causes of carbapatite stones induce IVa1 or IVb subtype, distal acidification defects are associated with IVa2 subtype in 90 % of cases (Fig. 8) [9]. Such findings illustrate the significance of morpho-constitutional analysis helping to find clinical diagnosis.Fig. 8


Kidney stone analysis: "Give me your stone, I will tell you who you are!".

Cloutier J, Villa L, Traxer O, Daudon M - World J Urol (2014)

Calcium phosphate stones mainly composed of carbapatite: a subtype IVa1 (surface); b subtype IVa1 (section); c subtype IVa2 (surface): note the glazed aspect and the presence of very tiny cracks; d subtype IVa2 (section); e subtype IVb (surface); f subtype IVb (section)
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4308647&req=5

Fig8: Calcium phosphate stones mainly composed of carbapatite: a subtype IVa1 (surface); b subtype IVa1 (section); c subtype IVa2 (surface): note the glazed aspect and the presence of very tiny cracks; d subtype IVa2 (section); e subtype IVb (surface); f subtype IVb (section)
Mentions: An infrequent cause of CaPh stones is a kidney cells impairment to excrete protons as observed in inherited distal acidification defect or acquired auto-immune diseases such as Sjogren’s syndrome. In such metabolic diseases, urinary calculi are mainly composed of carbapatite with a very high content of CaPh, often above 80 % of the stone mass. While most causes of carbapatite stones induce IVa1 or IVb subtype, distal acidification defects are associated with IVa2 subtype in 90 % of cases (Fig. 8) [9]. Such findings illustrate the significance of morpho-constitutional analysis helping to find clinical diagnosis.Fig. 8

Bottom Line: Stone analysis is an important part in the evaluation of patients having stone disease.Unfortunately, chemical methods often are inadequate to analyze accurately urinary calculi and could fail to detect some elements into the stone.Here, specific chemical types with their different crystalline phases are shown in connection with their different etiologies involved.

View Article: PubMed Central - PubMed

Affiliation: Urology Department, Tenon University Hospital, 4 rue de la Chine, 75970, Paris Cedex 20, France.

ABSTRACT

Introduction: Stone analysis is an important part in the evaluation of patients having stone disease. This could orientate the physician toward particular etiologies.

Material and methods: Chemical and physical methods are both used for analysis. Unfortunately, chemical methods often are inadequate to analyze accurately urinary calculi and could fail to detect some elements into the stone. Physical methods, in counterpart, are becoming more and more used in high-volume laboratories. The present manuscript will provide a review on analytic methods, and review all the information that should be included into an appropriate morpho-constitutional analysis.

Conclusion: This report can supply an excellent summarization of the stone morphology and give the opportunity to find specific metabolic disorders and different lithogenic process into the same stone. Here, specific chemical types with their different crystalline phases are shown in connection with their different etiologies involved.

Show MeSH
Related in: MedlinePlus