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Left ventricular global longitudinal strain is associated with exercise capacity in failing hearts with preserved and reduced ejection fraction.

Hasselberg NE, Haugaa KH, Sarvari SI, Gullestad L, Andreassen AK, Smiseth OA, Edvardsen T - Eur Heart J Cardiovasc Imaging (2014)

Bottom Line: LV systolic function, as EF and global longitudinal strain (GLS), and right ventricular function were assessed by echocardiography.LV GLS was superior to EF in identifying patients with impaired peak VO2 <20 mL/kg/min as shown by receiver operating characteristic analyses [areas under curves 0.93 (0.89-0.98) vs. 0.85 (0.77-0.93), P < 0.05].There was a significant relationship between diastolic function and GLS, confirming a coupling between diastolic and longitudinal systolic function in HFpEF.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Rikshospitalet, Oslo University Hospital, Sognsvannsveien 20, Oslo, Norway Center for Cardiological Innovation, Oslo, Norway Faculty of Medicine, University of Oslo, Oslo, Norway Institute for Surgical Research, Rikshospitalet, Oslo University Hospital, Oslo, Norway.

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Receiver operating characteristic curve analyses showing that GLS is superior to other myocardial function parameters to identify patients with a peak VO2 of <20 mL/kg/min (n = 100). AUC, area under curve; CI, confidence interval; E, peak early diastolic filling velocity; e′, early diastolic mitral annular velocity (septal).
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JEU277F3: Receiver operating characteristic curve analyses showing that GLS is superior to other myocardial function parameters to identify patients with a peak VO2 of <20 mL/kg/min (n = 100). AUC, area under curve; CI, confidence interval; E, peak early diastolic filling velocity; e′, early diastolic mitral annular velocity (septal).

Mentions: ROC analyses showed that GLS had significantly better ability to detect reduced peak VO2 of <20 mL/kg/min compared with EF, RV strain, and E/e′ (Figure 3). A GLS value of −17.3% had excellent sensitivity of 0.89 (95% CI 0.79–0.95) and specificity of 0.91 (95% CI 0.71–0.99) to identify patients with a peak VO2 of <20 mL/kg/min.Figure 3


Left ventricular global longitudinal strain is associated with exercise capacity in failing hearts with preserved and reduced ejection fraction.

Hasselberg NE, Haugaa KH, Sarvari SI, Gullestad L, Andreassen AK, Smiseth OA, Edvardsen T - Eur Heart J Cardiovasc Imaging (2014)

Receiver operating characteristic curve analyses showing that GLS is superior to other myocardial function parameters to identify patients with a peak VO2 of <20 mL/kg/min (n = 100). AUC, area under curve; CI, confidence interval; E, peak early diastolic filling velocity; e′, early diastolic mitral annular velocity (septal).
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4307775&req=5

JEU277F3: Receiver operating characteristic curve analyses showing that GLS is superior to other myocardial function parameters to identify patients with a peak VO2 of <20 mL/kg/min (n = 100). AUC, area under curve; CI, confidence interval; E, peak early diastolic filling velocity; e′, early diastolic mitral annular velocity (septal).
Mentions: ROC analyses showed that GLS had significantly better ability to detect reduced peak VO2 of <20 mL/kg/min compared with EF, RV strain, and E/e′ (Figure 3). A GLS value of −17.3% had excellent sensitivity of 0.89 (95% CI 0.79–0.95) and specificity of 0.91 (95% CI 0.71–0.99) to identify patients with a peak VO2 of <20 mL/kg/min.Figure 3

Bottom Line: LV systolic function, as EF and global longitudinal strain (GLS), and right ventricular function were assessed by echocardiography.LV GLS was superior to EF in identifying patients with impaired peak VO2 <20 mL/kg/min as shown by receiver operating characteristic analyses [areas under curves 0.93 (0.89-0.98) vs. 0.85 (0.77-0.93), P < 0.05].There was a significant relationship between diastolic function and GLS, confirming a coupling between diastolic and longitudinal systolic function in HFpEF.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Rikshospitalet, Oslo University Hospital, Sognsvannsveien 20, Oslo, Norway Center for Cardiological Innovation, Oslo, Norway Faculty of Medicine, University of Oslo, Oslo, Norway Institute for Surgical Research, Rikshospitalet, Oslo University Hospital, Oslo, Norway.

Show MeSH
Related in: MedlinePlus