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Intracranial Lesions with Low Signal Intensity on T2-weighted MR Images - Review of Pathologies.

Zimny A, Neska-Matuszewska M, Bladowska J, Sąsiadek MJ - Pol J Radiol (2015)

Bottom Line: In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images.Eight groups of substances were discussed i.e. 1.Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces.

View Article: PubMed Central - PubMed

Affiliation: Department of General and Interventional Radiology and Neuroradiology, Wrocław Medical University, Wrocław, Poland.

ABSTRACT
In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images. Eight groups of substances were discussed i.e. 1. Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces. Appropriate interpretation of signal intensity as well as analysis of lesion location and clinical symptoms enable a correct choice of a further diagnostic algorithm or, in many cases, final diagnosis based exclusively on an MRI examination.

No MeSH data available.


Related in: MedlinePlus

Aging brain. T2-weighted image (A) shows low signal of both globi pallidi due to iron accumulation in a 75-year-old female patient. Iron overload may be better visualized on T2* images (B).
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f13-poljradiol-80-40: Aging brain. T2-weighted image (A) shows low signal of both globi pallidi due to iron accumulation in a 75-year-old female patient. Iron overload may be better visualized on T2* images (B).

Mentions: During aging physiological lowering of T2 signal of the globus pallidus can be noted due to the accumulation of iron (Figure 13). High concentrations of iron can be found also in the red nucleus, substantia nigra and putamen but in these regions physiological lowering of T2 signal is not so strongly expressed. Iron has also a weaker effect on T1 relaxation but the resulting reduction in T1 times may produce hyperintensity on T1-weighted images [6,18].


Intracranial Lesions with Low Signal Intensity on T2-weighted MR Images - Review of Pathologies.

Zimny A, Neska-Matuszewska M, Bladowska J, Sąsiadek MJ - Pol J Radiol (2015)

Aging brain. T2-weighted image (A) shows low signal of both globi pallidi due to iron accumulation in a 75-year-old female patient. Iron overload may be better visualized on T2* images (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4307690&req=5

f13-poljradiol-80-40: Aging brain. T2-weighted image (A) shows low signal of both globi pallidi due to iron accumulation in a 75-year-old female patient. Iron overload may be better visualized on T2* images (B).
Mentions: During aging physiological lowering of T2 signal of the globus pallidus can be noted due to the accumulation of iron (Figure 13). High concentrations of iron can be found also in the red nucleus, substantia nigra and putamen but in these regions physiological lowering of T2 signal is not so strongly expressed. Iron has also a weaker effect on T1 relaxation but the resulting reduction in T1 times may produce hyperintensity on T1-weighted images [6,18].

Bottom Line: In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images.Eight groups of substances were discussed i.e. 1.Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces.

View Article: PubMed Central - PubMed

Affiliation: Department of General and Interventional Radiology and Neuroradiology, Wrocław Medical University, Wrocław, Poland.

ABSTRACT
In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images. Eight groups of substances were discussed i.e. 1. Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces. Appropriate interpretation of signal intensity as well as analysis of lesion location and clinical symptoms enable a correct choice of a further diagnostic algorithm or, in many cases, final diagnosis based exclusively on an MRI examination.

No MeSH data available.


Related in: MedlinePlus