Limits...
Intracranial Lesions with Low Signal Intensity on T2-weighted MR Images - Review of Pathologies.

Zimny A, Neska-Matuszewska M, Bladowska J, Sąsiadek MJ - Pol J Radiol (2015)

Bottom Line: In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images.Eight groups of substances were discussed i.e. 1.Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces.

View Article: PubMed Central - PubMed

Affiliation: Department of General and Interventional Radiology and Neuroradiology, Wrocław Medical University, Wrocław, Poland.

ABSTRACT
In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images. Eight groups of substances were discussed i.e. 1. Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces. Appropriate interpretation of signal intensity as well as analysis of lesion location and clinical symptoms enable a correct choice of a further diagnostic algorithm or, in many cases, final diagnosis based exclusively on an MRI examination.

No MeSH data available.


Related in: MedlinePlus

Chronic hemorrhagic infarction within the right hemisphere. T2-weighted image (A) shows a diffuse hypointense area indicating hemosiderin which is better visualized on a susceptibility-weighted image (B).
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4307690&req=5

f5-poljradiol-80-40: Chronic hemorrhagic infarction within the right hemisphere. T2-weighted image (A) shows a diffuse hypointense area indicating hemosiderin which is better visualized on a susceptibility-weighted image (B).

Mentions: Hemoglobin is a paramagnetic substance with unpaired electrons and strong nuclear magnetism that affects a large number of adjacent protons. Hemoglobin evolves in time from oxyhemoglobin, then deoxyhemoglobin to methemoglobin. Finally, it is broken down into ferritin and hemosiderin (Table 1). T2-hypointensity is characteristic for intracellular deoxyhemoglobin (acute phase of bleeding) (Figure 2), intracellular methemoglobin (early subacute phase of bleeding) (Figure 3) and hemosiderin (late phase of bleeding) (Figures 4 and 5). Intracellular deoxyhemoglobin and hemosiderin produce also hypointensity on T1-weighted images while methemoglobin appears as hyperintense on T1-weighted images (Table 1) [7].


Intracranial Lesions with Low Signal Intensity on T2-weighted MR Images - Review of Pathologies.

Zimny A, Neska-Matuszewska M, Bladowska J, Sąsiadek MJ - Pol J Radiol (2015)

Chronic hemorrhagic infarction within the right hemisphere. T2-weighted image (A) shows a diffuse hypointense area indicating hemosiderin which is better visualized on a susceptibility-weighted image (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4307690&req=5

f5-poljradiol-80-40: Chronic hemorrhagic infarction within the right hemisphere. T2-weighted image (A) shows a diffuse hypointense area indicating hemosiderin which is better visualized on a susceptibility-weighted image (B).
Mentions: Hemoglobin is a paramagnetic substance with unpaired electrons and strong nuclear magnetism that affects a large number of adjacent protons. Hemoglobin evolves in time from oxyhemoglobin, then deoxyhemoglobin to methemoglobin. Finally, it is broken down into ferritin and hemosiderin (Table 1). T2-hypointensity is characteristic for intracellular deoxyhemoglobin (acute phase of bleeding) (Figure 2), intracellular methemoglobin (early subacute phase of bleeding) (Figure 3) and hemosiderin (late phase of bleeding) (Figures 4 and 5). Intracellular deoxyhemoglobin and hemosiderin produce also hypointensity on T1-weighted images while methemoglobin appears as hyperintense on T1-weighted images (Table 1) [7].

Bottom Line: In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images.Eight groups of substances were discussed i.e. 1.Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces.

View Article: PubMed Central - PubMed

Affiliation: Department of General and Interventional Radiology and Neuroradiology, Wrocław Medical University, Wrocław, Poland.

ABSTRACT
In this article we presented intracranial pathological substances and lesions with low signal intensity on T2-weighted images. Eight groups of substances were discussed i.e. 1. Gadolinium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-containing lesions, 5. highly cellular lesions, 6. lesions containing mineral substances such as: calcium, copper and iron, 7. turbulent and rapid blood or CSF flow 8. air-containing spaces. Appropriate interpretation of signal intensity as well as analysis of lesion location and clinical symptoms enable a correct choice of a further diagnostic algorithm or, in many cases, final diagnosis based exclusively on an MRI examination.

No MeSH data available.


Related in: MedlinePlus