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Paratesticular liposarcoma; a case report.

Omidvari S, Hamedi SH, Moaddab-Shoar L, Nasrollahi H, Daneshbod Y, Mosleh-Shirazi MA, Ansrai M, Mohammadianpanah M, Ahmadloo N, Mosalaei A - Iran J Cancer Prev (2014)

Bottom Line: Multiple treatments have reported in literature with different results.After 18 months follow up, the patient was well and disease free.He has shown good response to surgery and radiotherapy, so we have reported the disease and its clinical course.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Radiation Oncology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT
Paratesticular sarcomas have happened rarely. Due to the infrequency of this malignant disease and its diverse histopathologic subtypes, no standard treatment would be available. Multiple treatments have reported in literature with different results. We have reported a 55 years old man with a 30 years history of paratesticular mass. After multiple operations, radical orchiectomy has revealed liposarcoma. The patient has been receiving 50 Gy radiation to the scrotum and inguinal area. After 18 months follow up, the patient was well and disease free. He has shown good response to surgery and radiotherapy, so we have reported the disease and its clinical course.

No MeSH data available.


Related in: MedlinePlus

Immuno-histochemical study has shown positivity for S100.
© Copyright Policy - open-access
Related In: Results  -  Collection

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f3-IJCP-07-239: Immuno-histochemical study has shown positivity for S100.

Mentions: A 55-year old man has left side inguinal hernia for 30 years but has received no treatment for it. He was a victim of chemical warfare in 1988, and had a Coronary Artery Bypass Graft (CABG) operation in 2005. In January 2010, a mass has appeared in his left scrotum. He had no pain or other symptoms such as fever or dysuria. Serum markers (LDH, AFP, βhCG) were normal. The patient has undergone mass excision in May 2010, and pathology has revealed lipoma. A mass has reappeared 1 year later. Based on the ultrasonography, the right testis was normal and a multi lobulated mass measuring 45×25×25 mm has seen in the left scrotum. The mass has excised again in July 2011 and pathology has shown a benign spindle cell tumor. None of operations were radical orchiectomy and adjuvant treatment has not administered. Three months later, the lesion has recurred for a second time. After reviewing pathology samples (from the 2nd operation), diagnosis of low grade malignant fibrous histiocytoma has made. In a pelvic CT scan, a hypo-attenuated mass has seen in the left scrotum (Figure 1). The patient has undergone left radical orchiectomy and high ligation of spermatic cord in November 2011. The tumor was a 7 cm creamy yellow, lobulated soft tissue attached to left testis without necrosis or hemorrhage (Figure 2). The surrounding testis has shown no pathology. In the IHC study, tumor cells were positive for CD68 and S100 (Figure 3). Well differentiated liposarcoma has diagnosed (Figure 4). According to the American Joint Committee on Cancer (AJCC) staging system for soft tissue sarcoma (7th ed, 2010), he had a T2aN0 or stage Ib lesion.


Paratesticular liposarcoma; a case report.

Omidvari S, Hamedi SH, Moaddab-Shoar L, Nasrollahi H, Daneshbod Y, Mosleh-Shirazi MA, Ansrai M, Mohammadianpanah M, Ahmadloo N, Mosalaei A - Iran J Cancer Prev (2014)

Immuno-histochemical study has shown positivity for S100.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4307107&req=5

f3-IJCP-07-239: Immuno-histochemical study has shown positivity for S100.
Mentions: A 55-year old man has left side inguinal hernia for 30 years but has received no treatment for it. He was a victim of chemical warfare in 1988, and had a Coronary Artery Bypass Graft (CABG) operation in 2005. In January 2010, a mass has appeared in his left scrotum. He had no pain or other symptoms such as fever or dysuria. Serum markers (LDH, AFP, βhCG) were normal. The patient has undergone mass excision in May 2010, and pathology has revealed lipoma. A mass has reappeared 1 year later. Based on the ultrasonography, the right testis was normal and a multi lobulated mass measuring 45×25×25 mm has seen in the left scrotum. The mass has excised again in July 2011 and pathology has shown a benign spindle cell tumor. None of operations were radical orchiectomy and adjuvant treatment has not administered. Three months later, the lesion has recurred for a second time. After reviewing pathology samples (from the 2nd operation), diagnosis of low grade malignant fibrous histiocytoma has made. In a pelvic CT scan, a hypo-attenuated mass has seen in the left scrotum (Figure 1). The patient has undergone left radical orchiectomy and high ligation of spermatic cord in November 2011. The tumor was a 7 cm creamy yellow, lobulated soft tissue attached to left testis without necrosis or hemorrhage (Figure 2). The surrounding testis has shown no pathology. In the IHC study, tumor cells were positive for CD68 and S100 (Figure 3). Well differentiated liposarcoma has diagnosed (Figure 4). According to the American Joint Committee on Cancer (AJCC) staging system for soft tissue sarcoma (7th ed, 2010), he had a T2aN0 or stage Ib lesion.

Bottom Line: Multiple treatments have reported in literature with different results.After 18 months follow up, the patient was well and disease free.He has shown good response to surgery and radiotherapy, so we have reported the disease and its clinical course.

View Article: PubMed Central - PubMed

Affiliation: Dept. of Radiation Oncology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT
Paratesticular sarcomas have happened rarely. Due to the infrequency of this malignant disease and its diverse histopathologic subtypes, no standard treatment would be available. Multiple treatments have reported in literature with different results. We have reported a 55 years old man with a 30 years history of paratesticular mass. After multiple operations, radical orchiectomy has revealed liposarcoma. The patient has been receiving 50 Gy radiation to the scrotum and inguinal area. After 18 months follow up, the patient was well and disease free. He has shown good response to surgery and radiotherapy, so we have reported the disease and its clinical course.

No MeSH data available.


Related in: MedlinePlus