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Health risk assessment for exposure to benzene in petroleum refinery environments.

Edokpolo B, Yu QJ, Connell D - Int J Environ Res Public Health (2015)

Bottom Line: Benzene levels were estimated to pose a significant risk with HQ50 > 1 and HQ95 > 1 for workers exposed to benzene as base estimates for petroleum refinery workers (Scenario 1), petroleum refinery workers evaluated with personal samplers in Bulgarian refineries (Scenario 2B) and evaluated using air inside petroleum refineries in Bulgarian refineries (Scenario 3B).HQ50 < 1 were calculated for petroleum refinery workers with personal samplers in Italian refineries (Scenario 2A), air inside petroleum refineries (Scenario 3A) and air outside petroleum refineries (Scenario 4) in India and Taiwan indicating little possible adverse health effects.Also, HQ95 was < 1 for Scenario 4 however potential risk was evaluated for Scenarios 2A and 3A with HQ95 > 1.

View Article: PubMed Central - PubMed

Affiliation: Griffith School of Engineering, Griffith University, Nathan Campus, Brisbane, QLD 4111, Australia. b.edokpolo@griffith.edu.au.

ABSTRACT
The health risk resulting from benzene exposure in petroleum refineries was calculated using data from the scientific literature from various countries throughout the world. The exposure data was collated into four scenarios from petroleum refinery environments and plotted as cumulative probability distributions (CPD) plots. Health risk was evaluated for each scenario using the Hazard Quotient (HQ) at 50% (CEXP50) and 95% (CEXP95) exposure levels. Benzene levels were estimated to pose a significant risk with HQ50 > 1 and HQ95 > 1 for workers exposed to benzene as base estimates for petroleum refinery workers (Scenario 1), petroleum refinery workers evaluated with personal samplers in Bulgarian refineries (Scenario 2B) and evaluated using air inside petroleum refineries in Bulgarian refineries (Scenario 3B). HQ50 < 1 were calculated for petroleum refinery workers with personal samplers in Italian refineries (Scenario 2A), air inside petroleum refineries (Scenario 3A) and air outside petroleum refineries (Scenario 4) in India and Taiwan indicating little possible adverse health effects. Also, HQ95 was < 1 for Scenario 4 however potential risk was evaluated for Scenarios 2A and 3A with HQ95 > 1. The excess Cancer risk (CR) for lifetime exposure to benzene for all the scenarios was evaluated using the Slope Factor and Overall Risk Probability (ORP) methods. The result suggests a potential cancer risk for exposure to benzene in all the scenarios. However, there is a higher cancer risk at 95% (CEXP95) for petroleum refinery workers (2B) with a CR of 48,000 per 106 and exposure to benzene in air inside petroleum refineries (3B) with a CR of 28,000 per 106.

No MeSH data available.


Related in: MedlinePlus

Overall risk probability (ORP) for cancer risk as a result of exposure to benzene concentrations in petroleum refinery environments.
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ijerph-12-00595-f006: Overall risk probability (ORP) for cancer risk as a result of exposure to benzene concentrations in petroleum refinery environments.

Mentions: Cancer risk adverse dose—response relationship are shown in Figure 5. The ORP plots are shown in Figure 6.The area under the ORP curves were calculated to obtain values of Overall Risk Probability (Table 4). ORP of 0.17% (1700 per 106) was obtained for Scenario 1 (base estimates for petroleum refinery workers), 0.011% (110 per 106) for Scenario 2A (petroleum refinery workers), 4.8% (48,000 per 106) for Scenario 2B (exposure to benzene for petroleum refinery workers), 0.015% (150 per 106) for Scenario 3A (benzene concentrations in air inside the petroleum refineries), 1.7% (17,000 per 106) for Scenario 3B (benzene concentrations in air inside the petroleum refineries) and 0.009% (110 per 106) for Scenario 4 (benzene concentrations in air outside the petroleum refineries).


Health risk assessment for exposure to benzene in petroleum refinery environments.

Edokpolo B, Yu QJ, Connell D - Int J Environ Res Public Health (2015)

Overall risk probability (ORP) for cancer risk as a result of exposure to benzene concentrations in petroleum refinery environments.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4306881&req=5

ijerph-12-00595-f006: Overall risk probability (ORP) for cancer risk as a result of exposure to benzene concentrations in petroleum refinery environments.
Mentions: Cancer risk adverse dose—response relationship are shown in Figure 5. The ORP plots are shown in Figure 6.The area under the ORP curves were calculated to obtain values of Overall Risk Probability (Table 4). ORP of 0.17% (1700 per 106) was obtained for Scenario 1 (base estimates for petroleum refinery workers), 0.011% (110 per 106) for Scenario 2A (petroleum refinery workers), 4.8% (48,000 per 106) for Scenario 2B (exposure to benzene for petroleum refinery workers), 0.015% (150 per 106) for Scenario 3A (benzene concentrations in air inside the petroleum refineries), 1.7% (17,000 per 106) for Scenario 3B (benzene concentrations in air inside the petroleum refineries) and 0.009% (110 per 106) for Scenario 4 (benzene concentrations in air outside the petroleum refineries).

Bottom Line: Benzene levels were estimated to pose a significant risk with HQ50 > 1 and HQ95 > 1 for workers exposed to benzene as base estimates for petroleum refinery workers (Scenario 1), petroleum refinery workers evaluated with personal samplers in Bulgarian refineries (Scenario 2B) and evaluated using air inside petroleum refineries in Bulgarian refineries (Scenario 3B).HQ50 < 1 were calculated for petroleum refinery workers with personal samplers in Italian refineries (Scenario 2A), air inside petroleum refineries (Scenario 3A) and air outside petroleum refineries (Scenario 4) in India and Taiwan indicating little possible adverse health effects.Also, HQ95 was < 1 for Scenario 4 however potential risk was evaluated for Scenarios 2A and 3A with HQ95 > 1.

View Article: PubMed Central - PubMed

Affiliation: Griffith School of Engineering, Griffith University, Nathan Campus, Brisbane, QLD 4111, Australia. b.edokpolo@griffith.edu.au.

ABSTRACT
The health risk resulting from benzene exposure in petroleum refineries was calculated using data from the scientific literature from various countries throughout the world. The exposure data was collated into four scenarios from petroleum refinery environments and plotted as cumulative probability distributions (CPD) plots. Health risk was evaluated for each scenario using the Hazard Quotient (HQ) at 50% (CEXP50) and 95% (CEXP95) exposure levels. Benzene levels were estimated to pose a significant risk with HQ50 > 1 and HQ95 > 1 for workers exposed to benzene as base estimates for petroleum refinery workers (Scenario 1), petroleum refinery workers evaluated with personal samplers in Bulgarian refineries (Scenario 2B) and evaluated using air inside petroleum refineries in Bulgarian refineries (Scenario 3B). HQ50 < 1 were calculated for petroleum refinery workers with personal samplers in Italian refineries (Scenario 2A), air inside petroleum refineries (Scenario 3A) and air outside petroleum refineries (Scenario 4) in India and Taiwan indicating little possible adverse health effects. Also, HQ95 was < 1 for Scenario 4 however potential risk was evaluated for Scenarios 2A and 3A with HQ95 > 1. The excess Cancer risk (CR) for lifetime exposure to benzene for all the scenarios was evaluated using the Slope Factor and Overall Risk Probability (ORP) methods. The result suggests a potential cancer risk for exposure to benzene in all the scenarios. However, there is a higher cancer risk at 95% (CEXP95) for petroleum refinery workers (2B) with a CR of 48,000 per 106 and exposure to benzene in air inside petroleum refineries (3B) with a CR of 28,000 per 106.

No MeSH data available.


Related in: MedlinePlus