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Noninvasive glaucoma procedures: current options and future innovations.

Abdelrahman AM - Middle East Afr J Ophthalmol (2015 Jan-Mar)

Bottom Line: Some of these procedures have shown good efficacy with few serious complications.The most common NIGPS involve laser and ultrasound technologies.Currently, the portfolio of NIGPs includes argon laser trabeculoplasty, selective laser trabeculoplasty, and micropulse diode laser trabeculoplasty.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Cairo University, Giza, Egypt.

ABSTRACT
Noninvasive glaucoma procedures (NIGPs) represent a new dawn in the management of glaucoma. They try to fill the gap between the shortcoming of invasive glaucoma surgeries and antiglaucoma medications. NIGPs were introduced as an adjunct or alternative treatments for glaucoma. Some of these procedures have shown good efficacy with few serious complications. Hence, they are now used as both primary and adjunctive therapy for glaucoma. The most common NIGPS involve laser and ultrasound technologies. Currently, the portfolio of NIGPs includes argon laser trabeculoplasty, selective laser trabeculoplasty, and micropulse diode laser trabeculoplasty. More recent innovations include therapeutic ultrasound for glaucoma, ultrasonic circular cyclocoagulation, and deep wave trabeculoplasty.

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Related in: MedlinePlus

Deep wave trabeculoplasty device from ocutherix and its application to the limbus (permission from Robert Atkinson)
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Related In: Results  -  Collection

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Figure 3: Deep wave trabeculoplasty device from ocutherix and its application to the limbus (permission from Robert Atkinson)

Mentions: The idea behind DWT was inspired from IOP-lowering effect of phacoemulsification. In DWT, mechanical oscillations are delivered to the TM using a handheld instrument positioned along the limbal region that overlies the TM [Figure 3]. The external application of mechanical energy (with much lower sonic frequency than phacoemulsification) causes focal stretching and relaxation of the TM. This induces a proposed IOP-reducing stress response in the TM cells, possibly through activation of an ELAM-1/IL-1/nuclear factor-kB response and release of cytokines. These changes are not associated with heat generation or tissue damage.


Noninvasive glaucoma procedures: current options and future innovations.

Abdelrahman AM - Middle East Afr J Ophthalmol (2015 Jan-Mar)

Deep wave trabeculoplasty device from ocutherix and its application to the limbus (permission from Robert Atkinson)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4302472&req=5

Figure 3: Deep wave trabeculoplasty device from ocutherix and its application to the limbus (permission from Robert Atkinson)
Mentions: The idea behind DWT was inspired from IOP-lowering effect of phacoemulsification. In DWT, mechanical oscillations are delivered to the TM using a handheld instrument positioned along the limbal region that overlies the TM [Figure 3]. The external application of mechanical energy (with much lower sonic frequency than phacoemulsification) causes focal stretching and relaxation of the TM. This induces a proposed IOP-reducing stress response in the TM cells, possibly through activation of an ELAM-1/IL-1/nuclear factor-kB response and release of cytokines. These changes are not associated with heat generation or tissue damage.

Bottom Line: Some of these procedures have shown good efficacy with few serious complications.The most common NIGPS involve laser and ultrasound technologies.Currently, the portfolio of NIGPs includes argon laser trabeculoplasty, selective laser trabeculoplasty, and micropulse diode laser trabeculoplasty.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Cairo University, Giza, Egypt.

ABSTRACT
Noninvasive glaucoma procedures (NIGPs) represent a new dawn in the management of glaucoma. They try to fill the gap between the shortcoming of invasive glaucoma surgeries and antiglaucoma medications. NIGPs were introduced as an adjunct or alternative treatments for glaucoma. Some of these procedures have shown good efficacy with few serious complications. Hence, they are now used as both primary and adjunctive therapy for glaucoma. The most common NIGPS involve laser and ultrasound technologies. Currently, the portfolio of NIGPs includes argon laser trabeculoplasty, selective laser trabeculoplasty, and micropulse diode laser trabeculoplasty. More recent innovations include therapeutic ultrasound for glaucoma, ultrasonic circular cyclocoagulation, and deep wave trabeculoplasty.

Show MeSH
Related in: MedlinePlus