Limits...
Prevalence of Precancerous Conditions and Gastric Cancer Based upon the National Cancer Screening Program in Korea for 7 Years, Single Center Experience.

Kang JH, Lim YJ, Kang JH, Yang JN, Shin SM, Choi JH, Lee JH - Gastroenterol Res Pract (2015)

Bottom Line: The prevalence of metaplastic gastritis, peptic ulcer, adenoma, EGC, and AGC was significantly higher in men than in women.The prevalence of preneoplastic/neoplastic disease significantly increased with age.Through the NCSP, the early detection of gastric cancer might contribute to the decreased mortality rate due to gastric cancer in Korea.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.

ABSTRACT
Aims. Gastric cancer is the second most prevalent cancer and the third leading cause of cancer-related deaths in Korea. The National Cancer Screening Program (NCSP) has implemented esophagogastroduodenoscopy (EGD) biennially for all Koreans starting in their 40s. This study was conducted to estimate the clinical relevance of NCSP through identifying the prevalence of gastric disease, including cancer. Materials and Methods. Data from 40,821 subjects who received the screening EGD in the single center for 7 years were retrospectively investigated. Results. The overall prevalence of nonatrophic/atrophic/metaplastic gastritis, peptic ulcer, adenoma, early gastric cancer (EGC), and advanced gastric cancer (AGC) was 44.28%, 27.97%, 14.95%, 0.59%, 0.43%, 0.21%, and 0.09%, respectively. The prevalence of metaplastic gastritis, peptic ulcer, adenoma, EGC, and AGC was significantly higher in men than in women. The prevalence of preneoplastic/neoplastic disease significantly increased with age. Judged from the ratio of EGC to AGC, the proportion of EGC made up to 70% of all cancers. Conclusions. Screening endoscopy starting for people in their 40s should be strongly recommended for the elderly. Through the NCSP, the early detection of gastric cancer might contribute to the decreased mortality rate due to gastric cancer in Korea.

No MeSH data available.


Related in: MedlinePlus

Proportion of early gastric cancer and advanced gastric cancer among gastric cancer diagnosed through National Cancer Screening Program from October 2005 to April 2012. EGC: early gastric cancer; AGC: advanced gastric cancer.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4302356&req=5

fig3: Proportion of early gastric cancer and advanced gastric cancer among gastric cancer diagnosed through National Cancer Screening Program from October 2005 to April 2012. EGC: early gastric cancer; AGC: advanced gastric cancer.

Mentions: In particular, the prevalence rate of atrophic gastritis and metaplastic gastritis was highest in individuals in their 70s. In comparison, the highest prevalence of adenomas and gastric cancer was in subjects over 80 years (Figure 2). One hundred twenty-three gastric cancers (0.3%) were diagnosed through NCSP during the 7-year study period. The incidence rate of EGC and AGC was 0.21% (n = 86) and 0.09% (n = 37), respectively. EGC comprised 70% of the gastric cancers (Figure 3), and the EGC/AGC ratio was 2.32 (86/37).


Prevalence of Precancerous Conditions and Gastric Cancer Based upon the National Cancer Screening Program in Korea for 7 Years, Single Center Experience.

Kang JH, Lim YJ, Kang JH, Yang JN, Shin SM, Choi JH, Lee JH - Gastroenterol Res Pract (2015)

Proportion of early gastric cancer and advanced gastric cancer among gastric cancer diagnosed through National Cancer Screening Program from October 2005 to April 2012. EGC: early gastric cancer; AGC: advanced gastric cancer.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4302356&req=5

fig3: Proportion of early gastric cancer and advanced gastric cancer among gastric cancer diagnosed through National Cancer Screening Program from October 2005 to April 2012. EGC: early gastric cancer; AGC: advanced gastric cancer.
Mentions: In particular, the prevalence rate of atrophic gastritis and metaplastic gastritis was highest in individuals in their 70s. In comparison, the highest prevalence of adenomas and gastric cancer was in subjects over 80 years (Figure 2). One hundred twenty-three gastric cancers (0.3%) were diagnosed through NCSP during the 7-year study period. The incidence rate of EGC and AGC was 0.21% (n = 86) and 0.09% (n = 37), respectively. EGC comprised 70% of the gastric cancers (Figure 3), and the EGC/AGC ratio was 2.32 (86/37).

Bottom Line: The prevalence of metaplastic gastritis, peptic ulcer, adenoma, EGC, and AGC was significantly higher in men than in women.The prevalence of preneoplastic/neoplastic disease significantly increased with age.Through the NCSP, the early detection of gastric cancer might contribute to the decreased mortality rate due to gastric cancer in Korea.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.

ABSTRACT
Aims. Gastric cancer is the second most prevalent cancer and the third leading cause of cancer-related deaths in Korea. The National Cancer Screening Program (NCSP) has implemented esophagogastroduodenoscopy (EGD) biennially for all Koreans starting in their 40s. This study was conducted to estimate the clinical relevance of NCSP through identifying the prevalence of gastric disease, including cancer. Materials and Methods. Data from 40,821 subjects who received the screening EGD in the single center for 7 years were retrospectively investigated. Results. The overall prevalence of nonatrophic/atrophic/metaplastic gastritis, peptic ulcer, adenoma, early gastric cancer (EGC), and advanced gastric cancer (AGC) was 44.28%, 27.97%, 14.95%, 0.59%, 0.43%, 0.21%, and 0.09%, respectively. The prevalence of metaplastic gastritis, peptic ulcer, adenoma, EGC, and AGC was significantly higher in men than in women. The prevalence of preneoplastic/neoplastic disease significantly increased with age. Judged from the ratio of EGC to AGC, the proportion of EGC made up to 70% of all cancers. Conclusions. Screening endoscopy starting for people in their 40s should be strongly recommended for the elderly. Through the NCSP, the early detection of gastric cancer might contribute to the decreased mortality rate due to gastric cancer in Korea.

No MeSH data available.


Related in: MedlinePlus