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Epidemiological and clinical evaluation of children with respiratory virus infections.

Shatizadeh S, Yavarian J, Rezaie F, Mahmoodi M, Naseri M, Mokhtari Azad T - Med J Islam Repub Iran (2014)

Bottom Line: This study was performed to detect viruses in children with respiratory infections and describe their epidemiology and clinical characteristics.RSV causes the great majority of respiratory virus infections in children.There was no significant difference in epidemiologic patterns of these viruses in comparison to other studies.

View Article: PubMed Central - HTML - PubMed

Affiliation: 1. MSc, PhD student of Virology, Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. shatizadeh@razi.tums.ac.ir.

ABSTRACT

Background: Respiratory viruses are the leading cause of respiratory tract infections among children and are responsible for causing morbidity and mortality worldwide. This study was performed to detect viruses in children with respiratory infections and describe their epidemiology and clinical characteristics.

Methods: In this descriptive cross sectional study, throat swabs and wash specimens from 202 children younger than six years of age with diagnosis of a respiratory tract infection from a total of 897 specimens were evaluated using multiplex PCR method.

Results: Respiratory viruses were detected in 92 children: respiratory synsytial virus, 16.8%; influenza virus, 5.4%; parainfluenza virus, 8.4%; adenovirus, 14.4% and human metapneumo virus 0.49% with male predominance and higher distribution in children younger than 1 year of age with preference in the cold months of year. The clinical presentations of all detected viruses were almost similar.

Conclusion: In the present study, nine different respiratory viruses were detected. RSV causes the great majority of respiratory virus infections in children. There was no significant difference in epidemiologic patterns of these viruses in comparison to other studies.

No MeSH data available.


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Mentions: The proportions of the patients aged <12, 12-24, 25-36, 37-48, 49-60 and 61-72 months were 16.3, 10.89, 2.97, 4.45, 3.46 and 6.93% respectively. Figure 1 shows age distribution of the children according to the different viruses. Among the patients there were 47(23.26%) males and 45(22.27%) females with a sex ratio of 1.04:1. Female sex was more frequently associated with RSV, PIV-1, IFV and hMPV in contrast AdV was detected mostly in males (Fig.2). Figure 3 and figure 4 show seasonal and monthly distribution according to the different viruses, respectively. In analyses of the clinical signs and symptoms in affected children, fever (53.6%) myalgia (49.8%) and cough (38.4%) were common clinical findings. Sore throat was observed in 25.3% of the patients. There were no headache and malaise found in these patients (Fig.5).


Epidemiological and clinical evaluation of children with respiratory virus infections.

Shatizadeh S, Yavarian J, Rezaie F, Mahmoodi M, Naseri M, Mokhtari Azad T - Med J Islam Repub Iran (2014)

© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4301222&req=5

Mentions: The proportions of the patients aged <12, 12-24, 25-36, 37-48, 49-60 and 61-72 months were 16.3, 10.89, 2.97, 4.45, 3.46 and 6.93% respectively. Figure 1 shows age distribution of the children according to the different viruses. Among the patients there were 47(23.26%) males and 45(22.27%) females with a sex ratio of 1.04:1. Female sex was more frequently associated with RSV, PIV-1, IFV and hMPV in contrast AdV was detected mostly in males (Fig.2). Figure 3 and figure 4 show seasonal and monthly distribution according to the different viruses, respectively. In analyses of the clinical signs and symptoms in affected children, fever (53.6%) myalgia (49.8%) and cough (38.4%) were common clinical findings. Sore throat was observed in 25.3% of the patients. There were no headache and malaise found in these patients (Fig.5).

Bottom Line: This study was performed to detect viruses in children with respiratory infections and describe their epidemiology and clinical characteristics.RSV causes the great majority of respiratory virus infections in children.There was no significant difference in epidemiologic patterns of these viruses in comparison to other studies.

View Article: PubMed Central - HTML - PubMed

Affiliation: 1. MSc, PhD student of Virology, Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. shatizadeh@razi.tums.ac.ir.

ABSTRACT

Background: Respiratory viruses are the leading cause of respiratory tract infections among children and are responsible for causing morbidity and mortality worldwide. This study was performed to detect viruses in children with respiratory infections and describe their epidemiology and clinical characteristics.

Methods: In this descriptive cross sectional study, throat swabs and wash specimens from 202 children younger than six years of age with diagnosis of a respiratory tract infection from a total of 897 specimens were evaluated using multiplex PCR method.

Results: Respiratory viruses were detected in 92 children: respiratory synsytial virus, 16.8%; influenza virus, 5.4%; parainfluenza virus, 8.4%; adenovirus, 14.4% and human metapneumo virus 0.49% with male predominance and higher distribution in children younger than 1 year of age with preference in the cold months of year. The clinical presentations of all detected viruses were almost similar.

Conclusion: In the present study, nine different respiratory viruses were detected. RSV causes the great majority of respiratory virus infections in children. There was no significant difference in epidemiologic patterns of these viruses in comparison to other studies.

No MeSH data available.


Related in: MedlinePlus