Limits...
A comparison of risk factors and severity of ischemic stroke in female and male genders in North-West Iran: A cross-sectional study.

Talebi M, Ghertasi M, Taheraghdam A, Andalib S, Sharifipour E - Iran J Neurol (2014)

Bottom Line: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability).No significant difference was seen in other risk factors between two genders.There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

ABSTRACT

Background: Gender difference has been reported in stroke risk factors and disease history. The aim of this study was to compare risk factors and the severity of ischemic stroke based upon modified Rankin Scale (mRS) and hospital mortality between two genders.

Methods: In a cross-sectional study, 341 patients (44% males and 56% females with a mean age of 68.94 ± 12.74 years) with ischemic stroke, who were hospitalized in the neurology wards of two referral university hospital of North-West Iran (Imam Reza and Razi Hospitals), from the beginning to the end of 2011 were selected and assessed. Gender difference in terms of demographic findings, vascular risk factors, 7(th) day mRS, and hospital mortality (during admission) were evaluated.

Results: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability). No significant difference in ischemic stroke severity based on mRS was observed between two genders. There was a significant difference in the rate of hypertension (females = 72.3%, males = 59.3%, P = 0.010), diabetes (females = 28.8%, males = 18.7%, P = 0.030), smoking (females = 6.3%, males = 35.3%, P < 0.001). No significant difference was seen in other risk factors between two genders. There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

Conclusion: The evidence from the present study suggests that despite the existence of some difference between risk-factors in two genders, there was no difference in terms of ischemic stroke severity and mortality rate between two genders.

No MeSH data available.


Related in: MedlinePlus

Modified Rankin Scale in both genders
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4300796&req=5

Figure 2: Modified Rankin Scale in both genders

Mentions: Figure 2 depicts mRS ranking in both genders. No significant difference was found between two genders (P = 0.510). Mortality rate was 7.0% (4.7% in male and 8.9% in female). In spite of the high mortality rate in female, the difference was non-significant (P = 0.140). AF patients showed a higher mortality rate [18.8% (6 cases)] than non-AF patients [5.8% (18 cases)] (P = 0.010). Significant variables between two genders, that is, hypertension, diabetes, and smoking were assessed using logistic regression analysis; and as a result, hypertension [P = 0.03, odds ratio (OR) = 1.72, confidence interval (CI) = 1.04-2.84] and smoking (P < 0.001, OR = 2.18, CI = 1.81-3.56) were better predictor of stroke in males, compared with females. Diabetes failed to show a significant role in this model (P = 0.110). Smoking exerted high harmful effects in causing stroke, compared with hypertension.


A comparison of risk factors and severity of ischemic stroke in female and male genders in North-West Iran: A cross-sectional study.

Talebi M, Ghertasi M, Taheraghdam A, Andalib S, Sharifipour E - Iran J Neurol (2014)

Modified Rankin Scale in both genders
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300796&req=5

Figure 2: Modified Rankin Scale in both genders
Mentions: Figure 2 depicts mRS ranking in both genders. No significant difference was found between two genders (P = 0.510). Mortality rate was 7.0% (4.7% in male and 8.9% in female). In spite of the high mortality rate in female, the difference was non-significant (P = 0.140). AF patients showed a higher mortality rate [18.8% (6 cases)] than non-AF patients [5.8% (18 cases)] (P = 0.010). Significant variables between two genders, that is, hypertension, diabetes, and smoking were assessed using logistic regression analysis; and as a result, hypertension [P = 0.03, odds ratio (OR) = 1.72, confidence interval (CI) = 1.04-2.84] and smoking (P < 0.001, OR = 2.18, CI = 1.81-3.56) were better predictor of stroke in males, compared with females. Diabetes failed to show a significant role in this model (P = 0.110). Smoking exerted high harmful effects in causing stroke, compared with hypertension.

Bottom Line: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability).No significant difference was seen in other risk factors between two genders.There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

ABSTRACT

Background: Gender difference has been reported in stroke risk factors and disease history. The aim of this study was to compare risk factors and the severity of ischemic stroke based upon modified Rankin Scale (mRS) and hospital mortality between two genders.

Methods: In a cross-sectional study, 341 patients (44% males and 56% females with a mean age of 68.94 ± 12.74 years) with ischemic stroke, who were hospitalized in the neurology wards of two referral university hospital of North-West Iran (Imam Reza and Razi Hospitals), from the beginning to the end of 2011 were selected and assessed. Gender difference in terms of demographic findings, vascular risk factors, 7(th) day mRS, and hospital mortality (during admission) were evaluated.

Results: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability). No significant difference in ischemic stroke severity based on mRS was observed between two genders. There was a significant difference in the rate of hypertension (females = 72.3%, males = 59.3%, P = 0.010), diabetes (females = 28.8%, males = 18.7%, P = 0.030), smoking (females = 6.3%, males = 35.3%, P < 0.001). No significant difference was seen in other risk factors between two genders. There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

Conclusion: The evidence from the present study suggests that despite the existence of some difference between risk-factors in two genders, there was no difference in terms of ischemic stroke severity and mortality rate between two genders.

No MeSH data available.


Related in: MedlinePlus