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A comparison of risk factors and severity of ischemic stroke in female and male genders in North-West Iran: A cross-sectional study.

Talebi M, Ghertasi M, Taheraghdam A, Andalib S, Sharifipour E - Iran J Neurol (2014)

Bottom Line: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability).No significant difference was seen in other risk factors between two genders.There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

ABSTRACT

Background: Gender difference has been reported in stroke risk factors and disease history. The aim of this study was to compare risk factors and the severity of ischemic stroke based upon modified Rankin Scale (mRS) and hospital mortality between two genders.

Methods: In a cross-sectional study, 341 patients (44% males and 56% females with a mean age of 68.94 ± 12.74 years) with ischemic stroke, who were hospitalized in the neurology wards of two referral university hospital of North-West Iran (Imam Reza and Razi Hospitals), from the beginning to the end of 2011 were selected and assessed. Gender difference in terms of demographic findings, vascular risk factors, 7(th) day mRS, and hospital mortality (during admission) were evaluated.

Results: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability). No significant difference in ischemic stroke severity based on mRS was observed between two genders. There was a significant difference in the rate of hypertension (females = 72.3%, males = 59.3%, P = 0.010), diabetes (females = 28.8%, males = 18.7%, P = 0.030), smoking (females = 6.3%, males = 35.3%, P < 0.001). No significant difference was seen in other risk factors between two genders. There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

Conclusion: The evidence from the present study suggests that despite the existence of some difference between risk-factors in two genders, there was no difference in terms of ischemic stroke severity and mortality rate between two genders.

No MeSH data available.


Related in: MedlinePlus

The frequency of modified Rankin Scale in the stroke patients
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Figure 1: The frequency of modified Rankin Scale in the stroke patients

Mentions: Of the 341 patients with ischemic stroke, there were 150 male (44%) and 191 female (56%). The mean age of the patients was 68.94 ± 12.74 years (27-97). No significant difference in the mean age of male and female patients, family history of stroke, history of stroke, hyperlipidemia, AF and other cardiac disease and drinking was observed between two genders (Table 1). Previous transient ischemic attack (TIA) history existed in 5 cases (1.5%). 3 (2%) in male and 2 (1%) in female. Hypertension was seen in 227 patients (66.6%). The mean duration of hypertension was 10.42 ± 6.52 years. Female had hypertension more than male (P = 0.010). There was no significant difference in previous cardiac disease history between male and female (P = 0.730) (Table 1). A total of 65 stroke patients (19.1%) were smokers with a mean duration of 31.12 ± 15.62 years. Smoking rate was very higher in male (53 cases) than in female (12 cases) (P < 0.001). Diabetes was found in 83 stroke patients (24.3%), and was observed to be more prevalent in female (55 cases) than in male (28 cases) P = 0.030. OCP was consumed in 10 female (5.2%) with a mean duration of 2.50 ± 2.12 years. Collagen vascular diseases existed in 8 stroke patients (2.3%), including 2 female (1.3%) and 6 male (3.1%). A mean mRS of 3.56 ± 3.56 with a mode of 4 was found in the stroke patients. Figure 1 illustrates the frequency of mRS in the stroke patients. As can be noted, the majority of stroke patients experienced moderately to severe disability. Nine stroke patients (2.6%) showed mRS of < 2 (favorable mRS), 332 cases (97.4%) with mRS of 2-5 (stroke patients with disability). The mean mRS in male and female was 3.46 ± 1.01 and 3.63 ± 0.94, respectively (P = 0.090).


A comparison of risk factors and severity of ischemic stroke in female and male genders in North-West Iran: A cross-sectional study.

Talebi M, Ghertasi M, Taheraghdam A, Andalib S, Sharifipour E - Iran J Neurol (2014)

The frequency of modified Rankin Scale in the stroke patients
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300796&req=5

Figure 1: The frequency of modified Rankin Scale in the stroke patients
Mentions: Of the 341 patients with ischemic stroke, there were 150 male (44%) and 191 female (56%). The mean age of the patients was 68.94 ± 12.74 years (27-97). No significant difference in the mean age of male and female patients, family history of stroke, history of stroke, hyperlipidemia, AF and other cardiac disease and drinking was observed between two genders (Table 1). Previous transient ischemic attack (TIA) history existed in 5 cases (1.5%). 3 (2%) in male and 2 (1%) in female. Hypertension was seen in 227 patients (66.6%). The mean duration of hypertension was 10.42 ± 6.52 years. Female had hypertension more than male (P = 0.010). There was no significant difference in previous cardiac disease history between male and female (P = 0.730) (Table 1). A total of 65 stroke patients (19.1%) were smokers with a mean duration of 31.12 ± 15.62 years. Smoking rate was very higher in male (53 cases) than in female (12 cases) (P < 0.001). Diabetes was found in 83 stroke patients (24.3%), and was observed to be more prevalent in female (55 cases) than in male (28 cases) P = 0.030. OCP was consumed in 10 female (5.2%) with a mean duration of 2.50 ± 2.12 years. Collagen vascular diseases existed in 8 stroke patients (2.3%), including 2 female (1.3%) and 6 male (3.1%). A mean mRS of 3.56 ± 3.56 with a mode of 4 was found in the stroke patients. Figure 1 illustrates the frequency of mRS in the stroke patients. As can be noted, the majority of stroke patients experienced moderately to severe disability. Nine stroke patients (2.6%) showed mRS of < 2 (favorable mRS), 332 cases (97.4%) with mRS of 2-5 (stroke patients with disability). The mean mRS in male and female was 3.46 ± 1.01 and 3.63 ± 0.94, respectively (P = 0.090).

Bottom Line: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability).No significant difference was seen in other risk factors between two genders.There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

View Article: PubMed Central - PubMed

Affiliation: Department of Neurology, Neurosciences Research Center (NSRC), School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

ABSTRACT

Background: Gender difference has been reported in stroke risk factors and disease history. The aim of this study was to compare risk factors and the severity of ischemic stroke based upon modified Rankin Scale (mRS) and hospital mortality between two genders.

Methods: In a cross-sectional study, 341 patients (44% males and 56% females with a mean age of 68.94 ± 12.74 years) with ischemic stroke, who were hospitalized in the neurology wards of two referral university hospital of North-West Iran (Imam Reza and Razi Hospitals), from the beginning to the end of 2011 were selected and assessed. Gender difference in terms of demographic findings, vascular risk factors, 7(th) day mRS, and hospital mortality (during admission) were evaluated.

Results: In 2.6% of cases, mRS was found to be less than 2 (favorable) and in 97.4% of cases; mRS was 2-5 (with disability). No significant difference in ischemic stroke severity based on mRS was observed between two genders. There was a significant difference in the rate of hypertension (females = 72.3%, males = 59.3%, P = 0.010), diabetes (females = 28.8%, males = 18.7%, P = 0.030), smoking (females = 6.3%, males = 35.3%, P < 0.001). No significant difference was seen in other risk factors between two genders. There was no significant difference in the mortality rate, which constituted 8.9% and 4.7% in females and males respectively (P = 0.140).

Conclusion: The evidence from the present study suggests that despite the existence of some difference between risk-factors in two genders, there was no difference in terms of ischemic stroke severity and mortality rate between two genders.

No MeSH data available.


Related in: MedlinePlus