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Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years.

Domayer SE, Welsch GH, Stelzeneder D, Hirschfeld C, Quirbach S, Nehrer S, Dorotka R, Mamisch TC, Trattnig S - Cartilage (2011)

Bottom Line: Both clinical scores demonstrated significant improvement at the time of the MR examination (P < 0.001).Relative T2 (rT2) was 1.00 ± 0.20 (range, 0.72-1.36).MFX in the ankle can provide RT with T2 properties similar to adjacent cartilage.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Medical University of Vienna, Vienna, Austria ; Department of Radiology, MR Center of Excellence, Medical University of Vienna, Vienna, Austria.

ABSTRACT

Background: Microfracture (MFX) is frequently used to treat deep cartilage defects in the ankle; however, the data on repair tissue (RT) quality after MFX are very limited at this time. T2-mapping at 3 T has been optimized for the ankle and can be used to noninvasively evaluate cartilage collagen and water content. The aim of this study was to determine if the RT after MFX in the ankle had T2 properties similar to the adjacent reference cartilage (RC).

Methods: Fourteen cases after MFX in the ankle were assessed with morphological MRI and T2-mapping at 3 T. The American Orthopaedic Foot and Ankle Society (AOFAS) score and a modified Cinicinnati Knee Rating System rating were used to evaluate the clinical outcome. The MRI protocol included a 3-dimensional sequence and a proton-density sequence for morphological evaluation and a multiecho spin echo sequence for T2-mapping. Region of interest analyses were carried out in accordance with the morphological images to ensure complete coverage of the defect site.

Results: Both clinical scores demonstrated significant improvement at the time of the MR examination (P < 0.001). RT T2 was 49.3 ± 10.1 (range, 35.7-69.3) milliseconds, and RC T2 was 49.9 ± 8.2 (range, 38.4-63.7) milliseconds (P = 0.838). Relative T2 (rT2) was 1.00 ± 0.20 (range, 0.72-1.36).

Conclusion: MFX in the ankle can provide RT with T2 properties similar to adjacent cartilage.

No MeSH data available.


Related in: MedlinePlus

Examples for T2-maps of cases 3 (A) and 4 (B). Despite obvious alterations of the subchondral bone, the T2 values of the repair tissue are similar to the adjacent native cartilage; in case 3 (A), a zonal organization of the T2 values can be seen; T2 is lower near the subchondral plate (blue) and increases toward the surface (green) both in the repair tissue and in the adjacent reference cartilage.
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fig3-1947603510380901: Examples for T2-maps of cases 3 (A) and 4 (B). Despite obvious alterations of the subchondral bone, the T2 values of the repair tissue are similar to the adjacent native cartilage; in case 3 (A), a zonal organization of the T2 values can be seen; T2 is lower near the subchondral plate (blue) and increases toward the surface (green) both in the repair tissue and in the adjacent reference cartilage.

Mentions: In the knee, a mean rT2 of 0.85 ± 0.10 (range, 0.61-1.02) was found in a series of 24 cases and 0.89 ± 0.12 (range, 0.78-1.03) in a series of 10 cases.28,33 The mean rT2 of 1.00 ± 0.20 (range, 0.72-1.36) found in the current series indicates that RT after MFX in the ankle has T2 properties more similar to those of native adjacent cartilage than found in the knee (Fig. 3).


Microfracture in the Ankle: Clinical Results and MRI with T2-Mapping at 3.0 T after 1 to 8 Years.

Domayer SE, Welsch GH, Stelzeneder D, Hirschfeld C, Quirbach S, Nehrer S, Dorotka R, Mamisch TC, Trattnig S - Cartilage (2011)

Examples for T2-maps of cases 3 (A) and 4 (B). Despite obvious alterations of the subchondral bone, the T2 values of the repair tissue are similar to the adjacent native cartilage; in case 3 (A), a zonal organization of the T2 values can be seen; T2 is lower near the subchondral plate (blue) and increases toward the surface (green) both in the repair tissue and in the adjacent reference cartilage.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4300787&req=5

fig3-1947603510380901: Examples for T2-maps of cases 3 (A) and 4 (B). Despite obvious alterations of the subchondral bone, the T2 values of the repair tissue are similar to the adjacent native cartilage; in case 3 (A), a zonal organization of the T2 values can be seen; T2 is lower near the subchondral plate (blue) and increases toward the surface (green) both in the repair tissue and in the adjacent reference cartilage.
Mentions: In the knee, a mean rT2 of 0.85 ± 0.10 (range, 0.61-1.02) was found in a series of 24 cases and 0.89 ± 0.12 (range, 0.78-1.03) in a series of 10 cases.28,33 The mean rT2 of 1.00 ± 0.20 (range, 0.72-1.36) found in the current series indicates that RT after MFX in the ankle has T2 properties more similar to those of native adjacent cartilage than found in the knee (Fig. 3).

Bottom Line: Both clinical scores demonstrated significant improvement at the time of the MR examination (P < 0.001).Relative T2 (rT2) was 1.00 ± 0.20 (range, 0.72-1.36).MFX in the ankle can provide RT with T2 properties similar to adjacent cartilage.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Medical University of Vienna, Vienna, Austria ; Department of Radiology, MR Center of Excellence, Medical University of Vienna, Vienna, Austria.

ABSTRACT

Background: Microfracture (MFX) is frequently used to treat deep cartilage defects in the ankle; however, the data on repair tissue (RT) quality after MFX are very limited at this time. T2-mapping at 3 T has been optimized for the ankle and can be used to noninvasively evaluate cartilage collagen and water content. The aim of this study was to determine if the RT after MFX in the ankle had T2 properties similar to the adjacent reference cartilage (RC).

Methods: Fourteen cases after MFX in the ankle were assessed with morphological MRI and T2-mapping at 3 T. The American Orthopaedic Foot and Ankle Society (AOFAS) score and a modified Cinicinnati Knee Rating System rating were used to evaluate the clinical outcome. The MRI protocol included a 3-dimensional sequence and a proton-density sequence for morphological evaluation and a multiecho spin echo sequence for T2-mapping. Region of interest analyses were carried out in accordance with the morphological images to ensure complete coverage of the defect site.

Results: Both clinical scores demonstrated significant improvement at the time of the MR examination (P < 0.001). RT T2 was 49.3 ± 10.1 (range, 35.7-69.3) milliseconds, and RC T2 was 49.9 ± 8.2 (range, 38.4-63.7) milliseconds (P = 0.838). Relative T2 (rT2) was 1.00 ± 0.20 (range, 0.72-1.36).

Conclusion: MFX in the ankle can provide RT with T2 properties similar to adjacent cartilage.

No MeSH data available.


Related in: MedlinePlus