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Noninvasive evaluation of left ventricular force-frequency relationships by measuring carotid arterial wave intensity during exercise stress.

Tanaka M, Sugawara M, Ogasawara Y, Suminoe I, Izumi T, Niki K, Kajiya F - J Med Ultrason (2001) (2014)

Bottom Line: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04).The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, Himeji, Hyogo 670-8524 Japan.

ABSTRACT

Background and purpose: Estimation of the contractility of the left ventricle during exercise is important in drawing up a protocol of cardiac rehabilitation. It has been demonstrated that color Doppler- and echo tracking-derived carotid arterial wave intensity is a sensitive index of global left ventricular (LV) contractility. We assessed the feasibility of measuring carotid arterial wave intensity and determining force-frequency (contractility-heart rate) relations (FFRs) during exercise totally noninvasively.

Methods: We measured carotid arterial wave intensity with a combined color Doppler and echo tracking system in 25 healthy young male volunteers (age 20.8 ± 1.2 years) at rest and during exercise. FFRs were constructed by plotting the maximum value of wave intensity (WD1) against heart rate (HR).

Results: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04). WD1 increased linearly with an increase in HR. The goodness-of-fit of the regression line of WD1 on HR in each subject was very high (r (2) = 0.48-0.94, p < 0.0001, respectively). The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].

Conclusions: Global LV FFRs can be generated in healthy young volunteers with an entirely noninvasive combination of exercise and wave intensity. These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

No MeSH data available.


Related in: MedlinePlus

A representative relation between heart rate (HR) (bpm) and work load (W) in healthy male subjects. The solid line indicates the linear regression line, and the dotted curves show the 95 % confidence band of the regression line
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Fig4: A representative relation between heart rate (HR) (bpm) and work load (W) in healthy male subjects. The solid line indicates the linear regression line, and the dotted curves show the 95 % confidence band of the regression line

Mentions: The baseline data from the subjects are shown in Table 1. We first confirmed that HR increased linearly with an increase in work load in all the subjects (r2 = 0.95 ± 0.04) (Fig. 4). WD1 increased linearly with an increase in HR (Fig. 5). The goodness-of-fit of the regression line of WD1 on HR in each subject was very high (r2 = 0.8 ± 0.1, p < 0.0001, respectively). The slope of the WD1-HR relation ranged from 0.30 to 2.20 [m/s3 (beat/min)] (mean ± SD: 1.0 ± 0.4 [m/s3 (beat/min)]). Figure 5 contains the WD1-HR relation with the greatest slope, that with the smallest slope, and those with moderate slopes.Fig. 4


Noninvasive evaluation of left ventricular force-frequency relationships by measuring carotid arterial wave intensity during exercise stress.

Tanaka M, Sugawara M, Ogasawara Y, Suminoe I, Izumi T, Niki K, Kajiya F - J Med Ultrason (2001) (2014)

A representative relation between heart rate (HR) (bpm) and work load (W) in healthy male subjects. The solid line indicates the linear regression line, and the dotted curves show the 95 % confidence band of the regression line
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4300423&req=5

Fig4: A representative relation between heart rate (HR) (bpm) and work load (W) in healthy male subjects. The solid line indicates the linear regression line, and the dotted curves show the 95 % confidence band of the regression line
Mentions: The baseline data from the subjects are shown in Table 1. We first confirmed that HR increased linearly with an increase in work load in all the subjects (r2 = 0.95 ± 0.04) (Fig. 4). WD1 increased linearly with an increase in HR (Fig. 5). The goodness-of-fit of the regression line of WD1 on HR in each subject was very high (r2 = 0.8 ± 0.1, p < 0.0001, respectively). The slope of the WD1-HR relation ranged from 0.30 to 2.20 [m/s3 (beat/min)] (mean ± SD: 1.0 ± 0.4 [m/s3 (beat/min)]). Figure 5 contains the WD1-HR relation with the greatest slope, that with the smallest slope, and those with moderate slopes.Fig. 4

Bottom Line: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04).The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, Himeji, Hyogo 670-8524 Japan.

ABSTRACT

Background and purpose: Estimation of the contractility of the left ventricle during exercise is important in drawing up a protocol of cardiac rehabilitation. It has been demonstrated that color Doppler- and echo tracking-derived carotid arterial wave intensity is a sensitive index of global left ventricular (LV) contractility. We assessed the feasibility of measuring carotid arterial wave intensity and determining force-frequency (contractility-heart rate) relations (FFRs) during exercise totally noninvasively.

Methods: We measured carotid arterial wave intensity with a combined color Doppler and echo tracking system in 25 healthy young male volunteers (age 20.8 ± 1.2 years) at rest and during exercise. FFRs were constructed by plotting the maximum value of wave intensity (WD1) against heart rate (HR).

Results: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04). WD1 increased linearly with an increase in HR. The goodness-of-fit of the regression line of WD1 on HR in each subject was very high (r (2) = 0.48-0.94, p < 0.0001, respectively). The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].

Conclusions: Global LV FFRs can be generated in healthy young volunteers with an entirely noninvasive combination of exercise and wave intensity. These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

No MeSH data available.


Related in: MedlinePlus