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Noninvasive evaluation of left ventricular force-frequency relationships by measuring carotid arterial wave intensity during exercise stress.

Tanaka M, Sugawara M, Ogasawara Y, Suminoe I, Izumi T, Niki K, Kajiya F - J Med Ultrason (2001) (2014)

Bottom Line: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04).The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, Himeji, Hyogo 670-8524 Japan.

ABSTRACT

Background and purpose: Estimation of the contractility of the left ventricle during exercise is important in drawing up a protocol of cardiac rehabilitation. It has been demonstrated that color Doppler- and echo tracking-derived carotid arterial wave intensity is a sensitive index of global left ventricular (LV) contractility. We assessed the feasibility of measuring carotid arterial wave intensity and determining force-frequency (contractility-heart rate) relations (FFRs) during exercise totally noninvasively.

Methods: We measured carotid arterial wave intensity with a combined color Doppler and echo tracking system in 25 healthy young male volunteers (age 20.8 ± 1.2 years) at rest and during exercise. FFRs were constructed by plotting the maximum value of wave intensity (WD1) against heart rate (HR).

Results: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04). WD1 increased linearly with an increase in HR. The goodness-of-fit of the regression line of WD1 on HR in each subject was very high (r (2) = 0.48-0.94, p < 0.0001, respectively). The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].

Conclusions: Global LV FFRs can be generated in healthy young volunteers with an entirely noninvasive combination of exercise and wave intensity. These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

No MeSH data available.


Related in: MedlinePlus

Relation between W1 obtained by carotid arterial echography and max dP/dt obtained with a catheter-tipped micromanometer (From Ohte N et al. [9])
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Fig1: Relation between W1 obtained by carotid arterial echography and max dP/dt obtained with a catheter-tipped micromanometer (From Ohte N et al. [9])

Mentions: During exercise, HR increases with an increase in workload; therefore, atrial pacing is not needed for changing HR. It has also been demonstrated that the peak dP/dt−HR relation is markedly enhanced (the slope is increased) during exercise compared with during pacing in normal hearts, but the enhancement is limited in diseased hearts [8]. The FFR obtained by exercise may have higher power to discriminate cardiac contractile states than that obtained by pacing. In spite of its potential for evaluating cardiac function during exercise, peak dP/dt−HR relation has not been widely used because of its invasive nature. We have reported that carotid arterial wave intensity (WI) noninvasively measured with a combined system of color Doppler and echo tracking is a sensitive index of global LV contractile function (Fig. 1) [9, 10].Fig. 1


Noninvasive evaluation of left ventricular force-frequency relationships by measuring carotid arterial wave intensity during exercise stress.

Tanaka M, Sugawara M, Ogasawara Y, Suminoe I, Izumi T, Niki K, Kajiya F - J Med Ultrason (2001) (2014)

Relation between W1 obtained by carotid arterial echography and max dP/dt obtained with a catheter-tipped micromanometer (From Ohte N et al. [9])
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4300423&req=5

Fig1: Relation between W1 obtained by carotid arterial echography and max dP/dt obtained with a catheter-tipped micromanometer (From Ohte N et al. [9])
Mentions: During exercise, HR increases with an increase in workload; therefore, atrial pacing is not needed for changing HR. It has also been demonstrated that the peak dP/dt−HR relation is markedly enhanced (the slope is increased) during exercise compared with during pacing in normal hearts, but the enhancement is limited in diseased hearts [8]. The FFR obtained by exercise may have higher power to discriminate cardiac contractile states than that obtained by pacing. In spite of its potential for evaluating cardiac function during exercise, peak dP/dt−HR relation has not been widely used because of its invasive nature. We have reported that carotid arterial wave intensity (WI) noninvasively measured with a combined system of color Doppler and echo tracking is a sensitive index of global LV contractile function (Fig. 1) [9, 10].Fig. 1

Bottom Line: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04).The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Health Care Sciences, Himeji Dokkyo University, 7-2-1 Kamiohno, Himeji, Hyogo 670-8524 Japan.

ABSTRACT

Background and purpose: Estimation of the contractility of the left ventricle during exercise is important in drawing up a protocol of cardiac rehabilitation. It has been demonstrated that color Doppler- and echo tracking-derived carotid arterial wave intensity is a sensitive index of global left ventricular (LV) contractility. We assessed the feasibility of measuring carotid arterial wave intensity and determining force-frequency (contractility-heart rate) relations (FFRs) during exercise totally noninvasively.

Methods: We measured carotid arterial wave intensity with a combined color Doppler and echo tracking system in 25 healthy young male volunteers (age 20.8 ± 1.2 years) at rest and during exercise. FFRs were constructed by plotting the maximum value of wave intensity (WD1) against heart rate (HR).

Results: We first confirmed that HR increased linearly with an increase in work load in each subject (r (2) = 0.95 ± 0.04). WD1 increased linearly with an increase in HR. The goodness-of-fit of the regression line of WD1 on HR in each subject was very high (r (2) = 0.48-0.94, p < 0.0001, respectively). The slope of the WD1-HR relation ranged 0.30-2.20 [m/s(3) (beat/min)].

Conclusions: Global LV FFRs can be generated in healthy young volunteers with an entirely noninvasive combination of exercise and wave intensity. These data should show the potential usefulness of the FFR in the context of cardiac rehabilitation.

No MeSH data available.


Related in: MedlinePlus