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Comparative biochemical analysis of three members of the Schistosoma mansoni TAL family: Differences in ion and drug binding properties.

Thomas CM, Fitzsimmons CM, Dunne DW, Timson DJ - Biochimie (2014)

Bottom Line: The tegumental allergen-like (TAL) proteins from Schistosoma mansoni are part of a family of calcium binding proteins found only in parasitic flatworms.Despite the presence of two EF-hand-like structures in SmTAL3, neither was predicted to be functional.Overall, these data suggest that the proteins have different biochemical properties and thus, most likely, different in vivo functions.

View Article: PubMed Central - PubMed

Affiliation: School of Biological Sciences, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, UK; Institute for Global Food Security, Queen's University Belfast, 18-30 Malone Road, Belfast, BT9 5BN, UK.

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Comparative biochemical analysis of three members of the Schistosoma mansoni TAL family: Differences in ion and drug binding properties.

Thomas CM, Fitzsimmons CM, Dunne DW, Timson DJ - Biochimie (2014)

© Copyright Policy - CC BY
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300400&req=5

Bottom Line: The tegumental allergen-like (TAL) proteins from Schistosoma mansoni are part of a family of calcium binding proteins found only in parasitic flatworms.Despite the presence of two EF-hand-like structures in SmTAL3, neither was predicted to be functional.Overall, these data suggest that the proteins have different biochemical properties and thus, most likely, different in vivo functions.

View Article: PubMed Central - PubMed

Affiliation: School of Biological Sciences, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, UK; Institute for Global Food Security, Queen's University Belfast, 18-30 Malone Road, Belfast, BT9 5BN, UK.

Show MeSH