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Herpes simplex virus type 1 infection in two pet marmosets in Japan.

Imura K, Chambers JK, Uchida K, Nomura S, Suzuki S, Nakayama H, Miwa Y - J. Vet. Med. Sci. (2014)

Bottom Line: Immunohistochemical examination using anti-herpes simplex virus type 1 antibody revealed virus antigens in both cases.Both animals had been kept as pets with limited exposure to the ambient environment except via their owners.Therefore, herpes simplex virus type-1 was probably acquired from close contact with their owners.

View Article: PubMed Central - PubMed

Affiliation: Miwa Exotic Animal Hospital, 1-25-5, Komagome, Toshima-ku, Tokyo 170-0003, Japan.

ABSTRACT
An 8-month-old common marmoset (Callithrix jacchus) was presented with tic-like symptoms, and a 2-year-old pigmy marmoset (Callithrix pygmaea) was presented with dyspnea and hypersalivation. Both monkeys died within a few days, and necropsies were performed. Histopathological examinations revealed ulcerative stomatitis with epithelial cell swelling and eosinophilic intranuclear inclusion bodies in the oral epithelium of both cases. In the central and peripheral nervous systems, neuronal cell degeneration with intranuclear inclusion bodies was observed. Immunohistochemical examination using anti-herpes simplex virus type 1 antibody revealed virus antigens in both cases. Both animals had been kept as pets with limited exposure to the ambient environment except via their owners. Therefore, herpes simplex virus type-1 was probably acquired from close contact with their owners.

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Related in: MedlinePlus

Eosinophilic intranuclear inclusion bodies in the enteric plexus ganglion cells of theinvaginated duodenum. HE, × 400. Case 2.
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fig_010: Eosinophilic intranuclear inclusion bodies in the enteric plexus ganglion cells of theinvaginated duodenum. HE, × 400. Case 2.

Mentions: Eosinophilic intranuclear inclusion bodies in epithelial cells of the tongue. Some aresurrounded by a clear halo, and others are faintly stained and fill the nucleus. HE, ×400. Case 2.


Herpes simplex virus type 1 infection in two pet marmosets in Japan.

Imura K, Chambers JK, Uchida K, Nomura S, Suzuki S, Nakayama H, Miwa Y - J. Vet. Med. Sci. (2014)

Eosinophilic intranuclear inclusion bodies in the enteric plexus ganglion cells of theinvaginated duodenum. HE, × 400. Case 2.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300388&req=5

fig_010: Eosinophilic intranuclear inclusion bodies in the enteric plexus ganglion cells of theinvaginated duodenum. HE, × 400. Case 2.
Mentions: Eosinophilic intranuclear inclusion bodies in epithelial cells of the tongue. Some aresurrounded by a clear halo, and others are faintly stained and fill the nucleus. HE, ×400. Case 2.

Bottom Line: Immunohistochemical examination using anti-herpes simplex virus type 1 antibody revealed virus antigens in both cases.Both animals had been kept as pets with limited exposure to the ambient environment except via their owners.Therefore, herpes simplex virus type-1 was probably acquired from close contact with their owners.

View Article: PubMed Central - PubMed

Affiliation: Miwa Exotic Animal Hospital, 1-25-5, Komagome, Toshima-ku, Tokyo 170-0003, Japan.

ABSTRACT
An 8-month-old common marmoset (Callithrix jacchus) was presented with tic-like symptoms, and a 2-year-old pigmy marmoset (Callithrix pygmaea) was presented with dyspnea and hypersalivation. Both monkeys died within a few days, and necropsies were performed. Histopathological examinations revealed ulcerative stomatitis with epithelial cell swelling and eosinophilic intranuclear inclusion bodies in the oral epithelium of both cases. In the central and peripheral nervous systems, neuronal cell degeneration with intranuclear inclusion bodies was observed. Immunohistochemical examination using anti-herpes simplex virus type 1 antibody revealed virus antigens in both cases. Both animals had been kept as pets with limited exposure to the ambient environment except via their owners. Therefore, herpes simplex virus type-1 was probably acquired from close contact with their owners.

Show MeSH
Related in: MedlinePlus