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Surgical and localized radiation therapy for an intranasal adenocarcinoma in a rabbit.

Nakata M, Miwa Y, Tsuboi M, Uchida K - J. Vet. Med. Sci. (2014)

Bottom Line: Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma.The prognosis has remained good for over 3 years after treatment.This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

View Article: PubMed Central - PubMed

Affiliation: Miwa Exotic Animal Hospital, 1-25-5 Komagome, Toshima-ku, 170-0003 Tokyo, Japan.

ABSTRACT
An 8-year-old spayed female Netherland Dwarf rabbit presented with a two-month history of dyspnea and snoring. A computed tomography (CT) scan of the head revealed mass lesions in the right nasal cavity. Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma. On the basis of this diagnosis, radiotherapy was planned and consisted of eight fractions of 6 Gy administered once a week. After the completion of radiation therapy, the soft tissue density in the right nasal cavity, as detected by CT, significantly decreased. The prognosis has remained good for over 3 years after treatment. This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

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Computed tomography (CT) scan of the head in the rabbit diagnosed with an intranasaladenocarcinoma. A soft tissue density in the transverse aspect within the right nasalcavity prior to radiation therapy (A) was significantly reduced after the completion ofthe radiation therapy (B).
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fig_004: Computed tomography (CT) scan of the head in the rabbit diagnosed with an intranasaladenocarcinoma. A soft tissue density in the transverse aspect within the right nasalcavity prior to radiation therapy (A) was significantly reduced after the completion ofthe radiation therapy (B).

Mentions: Radiation therapy was planned using an orthovoltage unit (MS-320R-2; Hitachi MedicalCorporation, Tokyo, Japan). Radiotherapy was initiated 4 weeks after surgery and consisted ofonce weekly administration of eight fractions of 6 Gy each over 8 consecutive weeks. Theradiation was single field irradiation, and the radiation field size was 4 × 4 cm (source toskin distance [SSD], 40 cm). The eyes of the rabbit were shielded with lead plates during theirradiation procedure. A CT scan (Asteion™ Super4; Toshiba Medical Systems Corporation) of thenasal cavity before irradiation revealed a small lesion of soft tissue density within theright nasal cavity extending to the rhinopharynx and an intact nasal septum in the transverseaspect (Fig. 4AFig. 4.


Surgical and localized radiation therapy for an intranasal adenocarcinoma in a rabbit.

Nakata M, Miwa Y, Tsuboi M, Uchida K - J. Vet. Med. Sci. (2014)

Computed tomography (CT) scan of the head in the rabbit diagnosed with an intranasaladenocarcinoma. A soft tissue density in the transverse aspect within the right nasalcavity prior to radiation therapy (A) was significantly reduced after the completion ofthe radiation therapy (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300386&req=5

fig_004: Computed tomography (CT) scan of the head in the rabbit diagnosed with an intranasaladenocarcinoma. A soft tissue density in the transverse aspect within the right nasalcavity prior to radiation therapy (A) was significantly reduced after the completion ofthe radiation therapy (B).
Mentions: Radiation therapy was planned using an orthovoltage unit (MS-320R-2; Hitachi MedicalCorporation, Tokyo, Japan). Radiotherapy was initiated 4 weeks after surgery and consisted ofonce weekly administration of eight fractions of 6 Gy each over 8 consecutive weeks. Theradiation was single field irradiation, and the radiation field size was 4 × 4 cm (source toskin distance [SSD], 40 cm). The eyes of the rabbit were shielded with lead plates during theirradiation procedure. A CT scan (Asteion™ Super4; Toshiba Medical Systems Corporation) of thenasal cavity before irradiation revealed a small lesion of soft tissue density within theright nasal cavity extending to the rhinopharynx and an intact nasal septum in the transverseaspect (Fig. 4AFig. 4.

Bottom Line: Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma.The prognosis has remained good for over 3 years after treatment.This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

View Article: PubMed Central - PubMed

Affiliation: Miwa Exotic Animal Hospital, 1-25-5 Komagome, Toshima-ku, 170-0003 Tokyo, Japan.

ABSTRACT
An 8-year-old spayed female Netherland Dwarf rabbit presented with a two-month history of dyspnea and snoring. A computed tomography (CT) scan of the head revealed mass lesions in the right nasal cavity. Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma. On the basis of this diagnosis, radiotherapy was planned and consisted of eight fractions of 6 Gy administered once a week. After the completion of radiation therapy, the soft tissue density in the right nasal cavity, as detected by CT, significantly decreased. The prognosis has remained good for over 3 years after treatment. This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

Show MeSH
Related in: MedlinePlus