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Surgical and localized radiation therapy for an intranasal adenocarcinoma in a rabbit.

Nakata M, Miwa Y, Tsuboi M, Uchida K - J. Vet. Med. Sci. (2014)

Bottom Line: Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma.The prognosis has remained good for over 3 years after treatment.This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

View Article: PubMed Central - PubMed

Affiliation: Miwa Exotic Animal Hospital, 1-25-5 Komagome, Toshima-ku, 170-0003 Tokyo, Japan.

ABSTRACT
An 8-year-old spayed female Netherland Dwarf rabbit presented with a two-month history of dyspnea and snoring. A computed tomography (CT) scan of the head revealed mass lesions in the right nasal cavity. Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma. On the basis of this diagnosis, radiotherapy was planned and consisted of eight fractions of 6 Gy administered once a week. After the completion of radiation therapy, the soft tissue density in the right nasal cavity, as detected by CT, significantly decreased. The prognosis has remained good for over 3 years after treatment. This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

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The exenteration of the intranasal mass lesion. The nasal cavity was exposed by meansof a dorsal midline approach using a carbon dioxide laser, and the mass attached to thenasal septum (arrowhead) and turbinates lining the nasal cavity was extirpated. Noobvious bone invasion or destruction was observed. The other rostral mass detected bycomputed tomography (CT) (Fig. 1) wasdetermined to be nasal discharge.
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fig_002: The exenteration of the intranasal mass lesion. The nasal cavity was exposed by meansof a dorsal midline approach using a carbon dioxide laser, and the mass attached to thenasal septum (arrowhead) and turbinates lining the nasal cavity was extirpated. Noobvious bone invasion or destruction was observed. The other rostral mass detected bycomputed tomography (CT) (Fig. 1) wasdetermined to be nasal discharge.

Mentions: Following premedication with an intramuscular injection of a combination of medetomidine (100µg/kg) and ketamine (5 mg/kg), isoflurane was administered to the rabbitvia a face mask. Subsequently, tracheal intubation was performed by a tracheostomy, with therabbit retained in the abdominal position. Exenteration of the intranasal mass lesions andtrephination of nasal bone were performed through a dorsal rhinotomy. In brief, the nasalcavity was entered through a dorsal midline approach, in which the nasal bone was carbonizedusing a carbon dioxide laser to expose the nasal turbinates and nasal cavity. The stoma wasextended using a rongeur, and the mass attached to the nasal septum and turbinates lining thenasal cavity was extirpated (Fig. 2Fig. 2.


Surgical and localized radiation therapy for an intranasal adenocarcinoma in a rabbit.

Nakata M, Miwa Y, Tsuboi M, Uchida K - J. Vet. Med. Sci. (2014)

The exenteration of the intranasal mass lesion. The nasal cavity was exposed by meansof a dorsal midline approach using a carbon dioxide laser, and the mass attached to thenasal septum (arrowhead) and turbinates lining the nasal cavity was extirpated. Noobvious bone invasion or destruction was observed. The other rostral mass detected bycomputed tomography (CT) (Fig. 1) wasdetermined to be nasal discharge.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300386&req=5

fig_002: The exenteration of the intranasal mass lesion. The nasal cavity was exposed by meansof a dorsal midline approach using a carbon dioxide laser, and the mass attached to thenasal septum (arrowhead) and turbinates lining the nasal cavity was extirpated. Noobvious bone invasion or destruction was observed. The other rostral mass detected bycomputed tomography (CT) (Fig. 1) wasdetermined to be nasal discharge.
Mentions: Following premedication with an intramuscular injection of a combination of medetomidine (100µg/kg) and ketamine (5 mg/kg), isoflurane was administered to the rabbitvia a face mask. Subsequently, tracheal intubation was performed by a tracheostomy, with therabbit retained in the abdominal position. Exenteration of the intranasal mass lesions andtrephination of nasal bone were performed through a dorsal rhinotomy. In brief, the nasalcavity was entered through a dorsal midline approach, in which the nasal bone was carbonizedusing a carbon dioxide laser to expose the nasal turbinates and nasal cavity. The stoma wasextended using a rongeur, and the mass attached to the nasal septum and turbinates lining thenasal cavity was extirpated (Fig. 2Fig. 2.

Bottom Line: Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma.The prognosis has remained good for over 3 years after treatment.This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

View Article: PubMed Central - PubMed

Affiliation: Miwa Exotic Animal Hospital, 1-25-5 Komagome, Toshima-ku, 170-0003 Tokyo, Japan.

ABSTRACT
An 8-year-old spayed female Netherland Dwarf rabbit presented with a two-month history of dyspnea and snoring. A computed tomography (CT) scan of the head revealed mass lesions in the right nasal cavity. Surgical exenteration of the lesions was performed, and the histopathological diagnosis was an intranasal adenocarcinoma. On the basis of this diagnosis, radiotherapy was planned and consisted of eight fractions of 6 Gy administered once a week. After the completion of radiation therapy, the soft tissue density in the right nasal cavity, as detected by CT, significantly decreased. The prognosis has remained good for over 3 years after treatment. This paper is the first to describe the clinical and pathological features of an intranasal tumor in a rabbit.

Show MeSH
Related in: MedlinePlus