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Duodenal bulb tumour of unknown origin.

Hankiewicz-Ziołkowska K, Soboń M, Szylberg T, Rudziński J - Prz Gastroenterol (2014)

Bottom Line: Their development typically depends on mutations in the Kit or PDGFRA gene.Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease.Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Gastroenterology, 10 Military Hospital with Policlinic, Bydgoszcz, Poland.

ABSTRACT
Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms of the gastrointestinal tract. Their development typically depends on mutations in the Kit or PDGFRA gene. We have diagnosed and treated a duodenal bulb GIST in a 63-year-old woman. The confirmation of the diagnosis was made on the basis of a histological test after radical resection of the tumour. Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease. Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

No MeSH data available.


Related in: MedlinePlus

CD117-positive cells in GIST structure. Immunohistochemical staining. Magnification 200×
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Figure 0005: CD117-positive cells in GIST structure. Immunohistochemical staining. Magnification 200×


Duodenal bulb tumour of unknown origin.

Hankiewicz-Ziołkowska K, Soboń M, Szylberg T, Rudziński J - Prz Gastroenterol (2014)

CD117-positive cells in GIST structure. Immunohistochemical staining. Magnification 200×
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300353&req=5

Figure 0005: CD117-positive cells in GIST structure. Immunohistochemical staining. Magnification 200×
Bottom Line: Their development typically depends on mutations in the Kit or PDGFRA gene.Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease.Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Gastroenterology, 10 Military Hospital with Policlinic, Bydgoszcz, Poland.

ABSTRACT
Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms of the gastrointestinal tract. Their development typically depends on mutations in the Kit or PDGFRA gene. We have diagnosed and treated a duodenal bulb GIST in a 63-year-old woman. The confirmation of the diagnosis was made on the basis of a histological test after radical resection of the tumour. Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease. Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

No MeSH data available.


Related in: MedlinePlus