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Duodenal bulb tumour of unknown origin.

Hankiewicz-Ziołkowska K, Soboń M, Szylberg T, Rudziński J - Prz Gastroenterol (2014)

Bottom Line: Their development typically depends on mutations in the Kit or PDGFRA gene.Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease.Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Gastroenterology, 10 Military Hospital with Policlinic, Bydgoszcz, Poland.

ABSTRACT
Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms of the gastrointestinal tract. Their development typically depends on mutations in the Kit or PDGFRA gene. We have diagnosed and treated a duodenal bulb GIST in a 63-year-old woman. The confirmation of the diagnosis was made on the basis of a histological test after radical resection of the tumour. Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease. Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

No MeSH data available.


Related in: MedlinePlus

Duodenal bulb tumour with lesion in gastroduodenoscopy
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Figure 0001: Duodenal bulb tumour with lesion in gastroduodenoscopy

Mentions: Ambulatory esophagogastroduodenoscopy revealed a polypoid change in the duodenum, 15 mm × 10 mm in diameter, narrowing the light of the intestine. Another esophagogastroduodenoscopy performed during hospitalisation confirmed the presence of a duodenal bulb tumour on the rear wall and the upper curve of the duodenum, 20 mm × 15 mm in diameter, raised to about 10 mm, with a lesion in the top, 6 mm × 8 mm in diameter, filled with inflammatory granulation tissue with visible, translucent, spontaneously bleeding vessels (Figures 1A–D).


Duodenal bulb tumour of unknown origin.

Hankiewicz-Ziołkowska K, Soboń M, Szylberg T, Rudziński J - Prz Gastroenterol (2014)

Duodenal bulb tumour with lesion in gastroduodenoscopy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4300353&req=5

Figure 0001: Duodenal bulb tumour with lesion in gastroduodenoscopy
Mentions: Ambulatory esophagogastroduodenoscopy revealed a polypoid change in the duodenum, 15 mm × 10 mm in diameter, narrowing the light of the intestine. Another esophagogastroduodenoscopy performed during hospitalisation confirmed the presence of a duodenal bulb tumour on the rear wall and the upper curve of the duodenum, 20 mm × 15 mm in diameter, raised to about 10 mm, with a lesion in the top, 6 mm × 8 mm in diameter, filled with inflammatory granulation tissue with visible, translucent, spontaneously bleeding vessels (Figures 1A–D).

Bottom Line: Their development typically depends on mutations in the Kit or PDGFRA gene.Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease.Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

View Article: PubMed Central - PubMed

Affiliation: Department of Clinical Gastroenterology, 10 Military Hospital with Policlinic, Bydgoszcz, Poland.

ABSTRACT
Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms of the gastrointestinal tract. Their development typically depends on mutations in the Kit or PDGFRA gene. We have diagnosed and treated a duodenal bulb GIST in a 63-year-old woman. The confirmation of the diagnosis was made on the basis of a histological test after radical resection of the tumour. Making the right diagnosis is crucial for patients, since complex surgical and pharmacological approaches are effective even in the advanced stages of the disease. Nevertheless, radical surgical treatment is still the primary choice for patients with GIST.

No MeSH data available.


Related in: MedlinePlus