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Magnetic resonance imaging-guided prostate biopsy: present and future.

Kim CK - Korean J Radiol (2015)

Bottom Line: The use of mp-MRI during a MRI-guided biopsy (MRGB) procedure improves the quality of a targeted biopsy.A MRGB seems accurate and efficient for the detection of clinically significant PCa in men with previous negative TRUSBx.Moreover, it may decrease the detection of clinically insignificant cancers with fewer biopsy cores.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.

ABSTRACT
Systemic transrectal ultrasound-guided biopsy (TRUSBx) is the standard procedure for diagnosing prostate cancer (PCa), but reveals a limited accuracy for the detection of cancer. Currently, multiparametric MR imaging (mp-MRI) is increasingly regarded as a promising method to detect PCa with an excellent positive predictive value. The use of mp-MRI during a MRI-guided biopsy (MRGB) procedure improves the quality of a targeted biopsy. The aim of this article is to provide an overview about the MRGB technique for PCa detection, to review the accuracy and clinical indications of MRGB and discuss its current issues and further directions. A MRGB seems accurate and efficient for the detection of clinically significant PCa in men with previous negative TRUSBx. Moreover, it may decrease the detection of clinically insignificant cancers with fewer biopsy cores.

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Related in: MedlinePlus

In-bore targeting devices.A. 150/175 mm 18-gauge automatic biopsy gun, prostate needle guide, bottles for sampled cores and lidocaine jelly are shown. B. Biopsy device with base plate for patient positioning (Invivo, Schwerin, Germany).
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Figure 2: In-bore targeting devices.A. 150/175 mm 18-gauge automatic biopsy gun, prostate needle guide, bottles for sampled cores and lidocaine jelly are shown. B. Biopsy device with base plate for patient positioning (Invivo, Schwerin, Germany).

Mentions: The in-bore targeting is performed with a transrectal approach within a MRI bore (5, 27, 28, 29). The radiologists fuse a previous MRI representing a lesion with a contemporaneous MRI to confirm the biopsy needle localization. Ideally, a few targeted biopsy cores are sampled. For performing this technique, a dedicated MR biopsy device is needed (Invivo, Schwerin, Germany) (Invivo DynaCAD, Invivo DynaTrim, prostate needle guide and 150/175 mm 18-gauge automatic biopsy gun) (Fig. 2). Its advantages include an exact direct targeting, reducing the detection of clinically insignificant cancer and obtaining a few biopsy cores. Its limitations include a long procedure time, expensive costs, two MRI sessions performed, potential false-negative findings and position difficulties.


Magnetic resonance imaging-guided prostate biopsy: present and future.

Kim CK - Korean J Radiol (2015)

In-bore targeting devices.A. 150/175 mm 18-gauge automatic biopsy gun, prostate needle guide, bottles for sampled cores and lidocaine jelly are shown. B. Biopsy device with base plate for patient positioning (Invivo, Schwerin, Germany).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4296281&req=5

Figure 2: In-bore targeting devices.A. 150/175 mm 18-gauge automatic biopsy gun, prostate needle guide, bottles for sampled cores and lidocaine jelly are shown. B. Biopsy device with base plate for patient positioning (Invivo, Schwerin, Germany).
Mentions: The in-bore targeting is performed with a transrectal approach within a MRI bore (5, 27, 28, 29). The radiologists fuse a previous MRI representing a lesion with a contemporaneous MRI to confirm the biopsy needle localization. Ideally, a few targeted biopsy cores are sampled. For performing this technique, a dedicated MR biopsy device is needed (Invivo, Schwerin, Germany) (Invivo DynaCAD, Invivo DynaTrim, prostate needle guide and 150/175 mm 18-gauge automatic biopsy gun) (Fig. 2). Its advantages include an exact direct targeting, reducing the detection of clinically insignificant cancer and obtaining a few biopsy cores. Its limitations include a long procedure time, expensive costs, two MRI sessions performed, potential false-negative findings and position difficulties.

Bottom Line: The use of mp-MRI during a MRI-guided biopsy (MRGB) procedure improves the quality of a targeted biopsy.A MRGB seems accurate and efficient for the detection of clinically significant PCa in men with previous negative TRUSBx.Moreover, it may decrease the detection of clinically insignificant cancers with fewer biopsy cores.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.

ABSTRACT
Systemic transrectal ultrasound-guided biopsy (TRUSBx) is the standard procedure for diagnosing prostate cancer (PCa), but reveals a limited accuracy for the detection of cancer. Currently, multiparametric MR imaging (mp-MRI) is increasingly regarded as a promising method to detect PCa with an excellent positive predictive value. The use of mp-MRI during a MRI-guided biopsy (MRGB) procedure improves the quality of a targeted biopsy. The aim of this article is to provide an overview about the MRGB technique for PCa detection, to review the accuracy and clinical indications of MRGB and discuss its current issues and further directions. A MRGB seems accurate and efficient for the detection of clinically significant PCa in men with previous negative TRUSBx. Moreover, it may decrease the detection of clinically insignificant cancers with fewer biopsy cores.

Show MeSH
Related in: MedlinePlus