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Attenuation-based automatic kilovoltage selection and sinogram-affirmed iterative reconstruction: effects on radiation exposure and image quality of portal-phase liver CT.

Song JS, Choi EJ, Kim EY, Kwak HS, Han YM - Korean J Radiol (2015)

Bottom Line: Reconstructed images were then qualitatively and quantitatively compared with protocol A images.Qualitative and quantitative analysis comparing S2 images from protocol B with images from protocol A, showed overall good diagnostic confidence of S2 images despite a significant radiation dose reduction (47% dose reduction, p < 0.001).Combined use of CARE kV and SAFIRE allowed significant reduction in radiation exposure while maintaining image quality in contrast-enhanced liver CT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Chonbuk National University Medical School and Hospital, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju 561-712, Korea.

ABSTRACT

Objective: To compare the radiation dose and image quality between standard-dose CT and a low-dose CT obtained with the combined use of an attenuation-based automatic kilovoltage (kV) selection tool (CARE kV) and sinogram-affirmed iterative reconstruction (SAFIRE) for contrast-enhanced CT examination of the liver.

Materials and methods: We retrospectively reviewed 67 patients with chronic liver disease in whom both, standard-dose CT with 64-slice multidetector-row CT (MDCT) (protocol A), and low-dose CT with 128-slice MDCT using CARE kV and SAFIRE (protocol B) were performed. Images from protocol B during the portal phase were reconstructed using either filtered back projection or SAFIRE with 5 different iterative reconstruction (IR) strengths. We performed qualitative and quantitative analyses to select the appropriate IR strength. Reconstructed images were then qualitatively and quantitatively compared with protocol A images.

Results: Qualitative and quantitative analysis of protocol B demonstrated that SAFIRE level 2 (S2) was most appropriate in our study. Qualitative and quantitative analysis comparing S2 images from protocol B with images from protocol A, showed overall good diagnostic confidence of S2 images despite a significant radiation dose reduction (47% dose reduction, p < 0.001).

Conclusion: Combined use of CARE kV and SAFIRE allowed significant reduction in radiation exposure while maintaining image quality in contrast-enhanced liver CT.

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Related in: MedlinePlus

Transverse contrast-enhanced liver CT images of 47-year-old female (body mass index, 22.4 kg/m2) with chronic hepatitis B.All images were obtained with tube voltage of 100 kV and 110 effective mAs (protocol B). Image noise decreased as SAFIRE level increased. However, as level increased, pixelated image appearance also increased.
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Figure 1: Transverse contrast-enhanced liver CT images of 47-year-old female (body mass index, 22.4 kg/m2) with chronic hepatitis B.All images were obtained with tube voltage of 100 kV and 110 effective mAs (protocol B). Image noise decreased as SAFIRE level increased. However, as level increased, pixelated image appearance also increased.

Mentions: The image quality scores determined by the 2 radiologists and the level of interobserver agreement were shown in Table 1. The image noise decreased significantly as the SAFIRE level increased (p < 0.05). Visibility of small anatomic structures and overall diagnostic confidence were the highest with S2 (4.0 ± 0.4, 4.1 ± 0.5). The pixelated image appearance increased as the SAFIRE level increased (Fig. 1). Interobserver agreement was moderate to almost perfect.


Attenuation-based automatic kilovoltage selection and sinogram-affirmed iterative reconstruction: effects on radiation exposure and image quality of portal-phase liver CT.

Song JS, Choi EJ, Kim EY, Kwak HS, Han YM - Korean J Radiol (2015)

Transverse contrast-enhanced liver CT images of 47-year-old female (body mass index, 22.4 kg/m2) with chronic hepatitis B.All images were obtained with tube voltage of 100 kV and 110 effective mAs (protocol B). Image noise decreased as SAFIRE level increased. However, as level increased, pixelated image appearance also increased.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4296279&req=5

Figure 1: Transverse contrast-enhanced liver CT images of 47-year-old female (body mass index, 22.4 kg/m2) with chronic hepatitis B.All images were obtained with tube voltage of 100 kV and 110 effective mAs (protocol B). Image noise decreased as SAFIRE level increased. However, as level increased, pixelated image appearance also increased.
Mentions: The image quality scores determined by the 2 radiologists and the level of interobserver agreement were shown in Table 1. The image noise decreased significantly as the SAFIRE level increased (p < 0.05). Visibility of small anatomic structures and overall diagnostic confidence were the highest with S2 (4.0 ± 0.4, 4.1 ± 0.5). The pixelated image appearance increased as the SAFIRE level increased (Fig. 1). Interobserver agreement was moderate to almost perfect.

Bottom Line: Reconstructed images were then qualitatively and quantitatively compared with protocol A images.Qualitative and quantitative analysis comparing S2 images from protocol B with images from protocol A, showed overall good diagnostic confidence of S2 images despite a significant radiation dose reduction (47% dose reduction, p < 0.001).Combined use of CARE kV and SAFIRE allowed significant reduction in radiation exposure while maintaining image quality in contrast-enhanced liver CT.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Chonbuk National University Medical School and Hospital, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju 561-712, Korea.

ABSTRACT

Objective: To compare the radiation dose and image quality between standard-dose CT and a low-dose CT obtained with the combined use of an attenuation-based automatic kilovoltage (kV) selection tool (CARE kV) and sinogram-affirmed iterative reconstruction (SAFIRE) for contrast-enhanced CT examination of the liver.

Materials and methods: We retrospectively reviewed 67 patients with chronic liver disease in whom both, standard-dose CT with 64-slice multidetector-row CT (MDCT) (protocol A), and low-dose CT with 128-slice MDCT using CARE kV and SAFIRE (protocol B) were performed. Images from protocol B during the portal phase were reconstructed using either filtered back projection or SAFIRE with 5 different iterative reconstruction (IR) strengths. We performed qualitative and quantitative analyses to select the appropriate IR strength. Reconstructed images were then qualitatively and quantitatively compared with protocol A images.

Results: Qualitative and quantitative analysis of protocol B demonstrated that SAFIRE level 2 (S2) was most appropriate in our study. Qualitative and quantitative analysis comparing S2 images from protocol B with images from protocol A, showed overall good diagnostic confidence of S2 images despite a significant radiation dose reduction (47% dose reduction, p < 0.001).

Conclusion: Combined use of CARE kV and SAFIRE allowed significant reduction in radiation exposure while maintaining image quality in contrast-enhanced liver CT.

Show MeSH
Related in: MedlinePlus