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Choroidal nevus in an eye with polypoidal choroidal vasculopathy.

Asao K, Hashida N, Nishida K - Case Rep Ophthalmol (2014)

Bottom Line: After the injection, PED improved and her visual acuity remained stable during the 12-month follow-up period.In cases of PCV, FAF images are helpful in determining the status of the posterior pole.Intravitreal injections of aflibercept can improve PED associated with CNV, and the BCVA will remain stable for at least 12 months.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.

ABSTRACT

Purpose: To report an eye with polypoidal choroidal vasculopathy (PCV) and a choroidal nevus.

Methods: This is an observational case report.

Results: A healthy 69-year-old woman was referred to the Osaka University Hospital with a diagnosis of a macular tumor. She complained of having distorted vision in her left eye. The medical history of the patient was unremarkable. At the initial examination, her best-corrected visual acuity (BCVA) was 20/20 in both eyes, and the intraocular pressure was 18 mm Hg in both eyes. A slit-lamp examination showed no abnormalities in the anterior segment of both eyes and a fundus examination of the left eye showed a slightly elevated juxtafoveal chorioretinal lesion and polyp-like reddish-orange lesions. The juxtafoveal choroidal lesion was located beneath a choroidal neovascularization (CNV). An optical coherence tomography confirmed CNV with pigment epithelial detachment (PED). Fluorescein angiography showed juxtafoveal hyperfluorescence due to CNV. Indocyanine green angiography demonstrated a branching choroidal vascular network that resembled polypoidal lesions. A fundus autofluorescence showed a mosaic pattern and a slight hyperautofluorescence at the CNV. We diagnosed the patient as having PCV. Aflibercept was injected intravitreally because of her PED. After the injection, PED improved and her visual acuity remained stable during the 12-month follow-up period.

Conclusions: In cases of PCV, FAF images are helpful in determining the status of the posterior pole. Intravitreal injections of aflibercept can improve PED associated with CNV, and the BCVA will remain stable for at least 12 months.

No MeSH data available.


Related in: MedlinePlus

A OCT confirms the presence of CNV with slight PED before the aflibercept injection. B The CNV is reduced after aflibercept injection.
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Figure 2: A OCT confirms the presence of CNV with slight PED before the aflibercept injection. B The CNV is reduced after aflibercept injection.

Mentions: We also performed OCT examinations with 3 OCT instruments: a Heidelberg Spectralis (Cirrus HD-OCT; Carl Zeiss Meditec, Inc., Dublin, Calif., USA), a Heidelberg Spectralis HRA + OCT (Heidelberg Engineering), and a prototype high-penetration OCT Topcon). The OCT examinations confirmed the CNV with an overlying PED, and the PED maintained (fig. 2a). Because of the PED, aflibercept was injected intravitreally which improved the PED (fig. 2b). Her VA remained stable for the 12-month follow-up period.


Choroidal nevus in an eye with polypoidal choroidal vasculopathy.

Asao K, Hashida N, Nishida K - Case Rep Ophthalmol (2014)

A OCT confirms the presence of CNV with slight PED before the aflibercept injection. B The CNV is reduced after aflibercept injection.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4296248&req=5

Figure 2: A OCT confirms the presence of CNV with slight PED before the aflibercept injection. B The CNV is reduced after aflibercept injection.
Mentions: We also performed OCT examinations with 3 OCT instruments: a Heidelberg Spectralis (Cirrus HD-OCT; Carl Zeiss Meditec, Inc., Dublin, Calif., USA), a Heidelberg Spectralis HRA + OCT (Heidelberg Engineering), and a prototype high-penetration OCT Topcon). The OCT examinations confirmed the CNV with an overlying PED, and the PED maintained (fig. 2a). Because of the PED, aflibercept was injected intravitreally which improved the PED (fig. 2b). Her VA remained stable for the 12-month follow-up period.

Bottom Line: After the injection, PED improved and her visual acuity remained stable during the 12-month follow-up period.In cases of PCV, FAF images are helpful in determining the status of the posterior pole.Intravitreal injections of aflibercept can improve PED associated with CNV, and the BCVA will remain stable for at least 12 months.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.

ABSTRACT

Purpose: To report an eye with polypoidal choroidal vasculopathy (PCV) and a choroidal nevus.

Methods: This is an observational case report.

Results: A healthy 69-year-old woman was referred to the Osaka University Hospital with a diagnosis of a macular tumor. She complained of having distorted vision in her left eye. The medical history of the patient was unremarkable. At the initial examination, her best-corrected visual acuity (BCVA) was 20/20 in both eyes, and the intraocular pressure was 18 mm Hg in both eyes. A slit-lamp examination showed no abnormalities in the anterior segment of both eyes and a fundus examination of the left eye showed a slightly elevated juxtafoveal chorioretinal lesion and polyp-like reddish-orange lesions. The juxtafoveal choroidal lesion was located beneath a choroidal neovascularization (CNV). An optical coherence tomography confirmed CNV with pigment epithelial detachment (PED). Fluorescein angiography showed juxtafoveal hyperfluorescence due to CNV. Indocyanine green angiography demonstrated a branching choroidal vascular network that resembled polypoidal lesions. A fundus autofluorescence showed a mosaic pattern and a slight hyperautofluorescence at the CNV. We diagnosed the patient as having PCV. Aflibercept was injected intravitreally because of her PED. After the injection, PED improved and her visual acuity remained stable during the 12-month follow-up period.

Conclusions: In cases of PCV, FAF images are helpful in determining the status of the posterior pole. Intravitreal injections of aflibercept can improve PED associated with CNV, and the BCVA will remain stable for at least 12 months.

No MeSH data available.


Related in: MedlinePlus