Salivary duct carcinoma with rhabdoid features: report of 2 cases with immunohistochemical and ultrastructural analyses.
Bottom Line: This submandibular tumor was also composed of both residual pleomorphic adenoma region and invasive adenocarcinoma components, whereas some metastatic lesions were purely composed of rhabdoid cells.Such cells were strongly and diffusely positive for cytokeratins (CKs), gross cystic disease fluid protein-15 (GCDFP), and androgen receptor (AR).Case 1 was also positive for Her-2 and p53.
Affiliation: Pathology Division, Shizuoka Cancer Center, Shizuoka, Japan.Show MeSH
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Mentions: Macroscopically, case 2 showed an ill-defined grayish-white mass with markedly cystic change in the right submandibular gland. A yellowish elastic-hard nodule was seen in this main mass (Figure 3A and 3B).
Affiliation: Pathology Division, Shizuoka Cancer Center, Shizuoka, Japan.