Evaluation of abdominal ultrasonography mass screening for hepatocellular carcinoma in Taiwan.
Bottom Line: This study aimed to assess the effectiveness of reducing HCC mortality by mass AUS screening for HCC based on a program designed and implemented in the Changhua Community-based Integrated Screening (CHCIS) program with an efficient invitation scheme guided by the risk score.The efficacy of reducing HCC mortality was estimated.The residents invited to community-based AUS screening for HCC, compared with those who were not invited, showed a reduction in HCC mortality by ∼ 31% among subjects aged 45-69 years who had not been included in the nationwide vaccination program against hepatitis B virus infection.
Affiliation: Changhua County Public Health Bureau, Changhua, Taiwan.Show MeSH
Related in: MedlinePlus
Mentions: The goodness of-fit results show the lack of a discrepancy between the observed and expected cells in the trained data (KCIS) (P = 0.2399 for Group A, and P = 0.2593 for Group B) and the validation data (CHCIS) (P = 0.5017 for Group A, and P = 0.5937 for Group B) (see the eAppendix Table A2). Figure 3 also shows the ROC curves for internal and external validation. Because the AUC values were 0.961 (95% CI: 0.939-0.983) for the trained dataset (KCIS) and 0.960 (95% CI: 0.932-0.988) for the validated dataset (CHCIS), the predictive validity of our proposed model was adequate.
Affiliation: Changhua County Public Health Bureau, Changhua, Taiwan.