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Evaluation of abdominal ultrasonography mass screening for hepatocellular carcinoma in Taiwan.

Yeh YP, Hu TH, Cho PY, Chen HH, Yen AM, Chen SL, Chiu SY, Fann JC, Su WW, Fang YJ, Chen ST, San HC, Chen HP, Liao CS, Changhua Community-Based Abdominal Ultrasonography Screening Gro - Hepatology (2014)

Bottom Line: This study aimed to assess the effectiveness of reducing HCC mortality by mass AUS screening for HCC based on a program designed and implemented in the Changhua Community-based Integrated Screening (CHCIS) program with an efficient invitation scheme guided by the risk score.The efficacy of reducing HCC mortality was estimated.The residents invited to community-based AUS screening for HCC, compared with those who were not invited, showed a reduction in HCC mortality by ∼ 31% among subjects aged 45-69 years who had not been included in the nationwide vaccination program against hepatitis B virus infection.

View Article: PubMed Central - PubMed

Affiliation: Changhua County Public Health Bureau, Changhua, Taiwan.

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The ROC curves for KCIS used to train the risk score and the external validation dataset with CHCIS.
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fig03: The ROC curves for KCIS used to train the risk score and the external validation dataset with CHCIS.

Mentions: The goodness of-fit results show the lack of a discrepancy between the observed and expected cells in the trained data (KCIS) (P = 0.2399 for Group A, and P = 0.2593 for Group B) and the validation data (CHCIS) (P = 0.5017 for Group A, and P = 0.5937 for Group B) (see the eAppendix Table A2). Figure 3 also shows the ROC curves for internal and external validation. Because the AUC values were 0.961 (95% CI: 0.939-0.983) for the trained dataset (KCIS) and 0.960 (95% CI: 0.932-0.988) for the validated dataset (CHCIS), the predictive validity of our proposed model was adequate.


Evaluation of abdominal ultrasonography mass screening for hepatocellular carcinoma in Taiwan.

Yeh YP, Hu TH, Cho PY, Chen HH, Yen AM, Chen SL, Chiu SY, Fann JC, Su WW, Fang YJ, Chen ST, San HC, Chen HP, Liao CS, Changhua Community-Based Abdominal Ultrasonography Screening Gro - Hepatology (2014)

The ROC curves for KCIS used to train the risk score and the external validation dataset with CHCIS.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4296217&req=5

fig03: The ROC curves for KCIS used to train the risk score and the external validation dataset with CHCIS.
Mentions: The goodness of-fit results show the lack of a discrepancy between the observed and expected cells in the trained data (KCIS) (P = 0.2399 for Group A, and P = 0.2593 for Group B) and the validation data (CHCIS) (P = 0.5017 for Group A, and P = 0.5937 for Group B) (see the eAppendix Table A2). Figure 3 also shows the ROC curves for internal and external validation. Because the AUC values were 0.961 (95% CI: 0.939-0.983) for the trained dataset (KCIS) and 0.960 (95% CI: 0.932-0.988) for the validated dataset (CHCIS), the predictive validity of our proposed model was adequate.

Bottom Line: This study aimed to assess the effectiveness of reducing HCC mortality by mass AUS screening for HCC based on a program designed and implemented in the Changhua Community-based Integrated Screening (CHCIS) program with an efficient invitation scheme guided by the risk score.The efficacy of reducing HCC mortality was estimated.The residents invited to community-based AUS screening for HCC, compared with those who were not invited, showed a reduction in HCC mortality by ∼ 31% among subjects aged 45-69 years who had not been included in the nationwide vaccination program against hepatitis B virus infection.

View Article: PubMed Central - PubMed

Affiliation: Changhua County Public Health Bureau, Changhua, Taiwan.

Show MeSH
Related in: MedlinePlus