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Prevalence of adenovirus respiratory tract and hiv co-infections in patients attending the University of Ilorin, teaching hospital, Ilorin, Nigeria.

Kolawole OM, Oladosu TO, Abdulkarim AA, Okoh AI - BMC Res Notes (2014)

Bottom Line: One Hundred and Eighty Four (184) patients were recruited with confirmed HIV positive status.Nevertheless, 62% (114 patients) tested negative to the co-infections.However, there was no significance with respect to gender of the subjects (p>0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry and Microbiology, Applied and Environmental Microbiology Research Group, University of Fort Hare, Alice, South Africa. tomak74@yahoo.com.

ABSTRACT

Background: Adenovirus co-infections in HIV patients cause wide-spread morbidity in sub-Saharan Africa, but little research has documented the burden and distribution of these pathogens. This study was conducted between December, 2010 and March, 2011 to investigate the prevalence of Adenovirus Respiratory Tract and HIV co-infections in Patients attending the University of Ilorin Teaching Hospital Ilorin, Nigeria.

Method: One Hundred and Eighty Four (184) patients were recruited with confirmed HIV positive status. Investigation was done by serology using the Human Adenovirus IgG ELISA Kit to test for the presence of the Immunoglobulin G (antibody) against the virus. This was conducted and juxtaposed simultaneously with responses received from the questionnaires provided to each participant to correlate the relationship of the co-infections to their socio-demographic factors (Age, Gender, Occupation and location of residence), risk factors (Average hours of exposure per day (time spent outdoor daily), proximity of their apartments to livestock settlements), recent occurrence of respiratory tract infections/conjunctivitis and their ART status.

Results: This study recorded a prevalent rate of 38% (70 patients) to the co-infections. Nevertheless, 62% (114 patients) tested negative to the co-infections.

Conclusion: There was statistical significance between the ages of HIV patients and Adenovirus co-infection (p<0.05). However, there was no significance with respect to gender of the subjects (p>0.05). The findings also showed that there were statistical significance for all the risk factors; Occupation, Location and Proximity to Livestock settlement, recent respiratory tract infection/conjunctivitis, and ART status in relation to Adenovirus and HIV co-infections (p<0.05).

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The prevalence of adenovirus co-infection in the HIV patients categorized by their locations and proximity of residence to livestock settlement. The p-value showed that there was significant difference between the locations and the proximity of the HIV Patients’ residence to Livestock Settlement with Adenovirus co-infection (p < 0.05).
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Fig2: The prevalence of adenovirus co-infection in the HIV patients categorized by their locations and proximity of residence to livestock settlement. The p-value showed that there was significant difference between the locations and the proximity of the HIV Patients’ residence to Livestock Settlement with Adenovirus co-infection (p < 0.05).

Mentions: The location of residence of patients was classified majorly into two groups; Urban and Rural settlements. The prevalence rate recorded in the urban settlers was slightly higher (39%) than what was recorded among the rural settlers (33%) (Figure 2). The p-value showed that there was significant difference between the locations of residence in HIV patients for both urban and rural dwellers, with Adenovirus co-infections (p < 0.05).Figure 1


Prevalence of adenovirus respiratory tract and hiv co-infections in patients attending the University of Ilorin, teaching hospital, Ilorin, Nigeria.

Kolawole OM, Oladosu TO, Abdulkarim AA, Okoh AI - BMC Res Notes (2014)

The prevalence of adenovirus co-infection in the HIV patients categorized by their locations and proximity of residence to livestock settlement. The p-value showed that there was significant difference between the locations and the proximity of the HIV Patients’ residence to Livestock Settlement with Adenovirus co-infection (p < 0.05).
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4289325&req=5

Fig2: The prevalence of adenovirus co-infection in the HIV patients categorized by their locations and proximity of residence to livestock settlement. The p-value showed that there was significant difference between the locations and the proximity of the HIV Patients’ residence to Livestock Settlement with Adenovirus co-infection (p < 0.05).
Mentions: The location of residence of patients was classified majorly into two groups; Urban and Rural settlements. The prevalence rate recorded in the urban settlers was slightly higher (39%) than what was recorded among the rural settlers (33%) (Figure 2). The p-value showed that there was significant difference between the locations of residence in HIV patients for both urban and rural dwellers, with Adenovirus co-infections (p < 0.05).Figure 1

Bottom Line: One Hundred and Eighty Four (184) patients were recruited with confirmed HIV positive status.Nevertheless, 62% (114 patients) tested negative to the co-infections.However, there was no significance with respect to gender of the subjects (p>0.05).

View Article: PubMed Central - PubMed

Affiliation: Department of Biochemistry and Microbiology, Applied and Environmental Microbiology Research Group, University of Fort Hare, Alice, South Africa. tomak74@yahoo.com.

ABSTRACT

Background: Adenovirus co-infections in HIV patients cause wide-spread morbidity in sub-Saharan Africa, but little research has documented the burden and distribution of these pathogens. This study was conducted between December, 2010 and March, 2011 to investigate the prevalence of Adenovirus Respiratory Tract and HIV co-infections in Patients attending the University of Ilorin Teaching Hospital Ilorin, Nigeria.

Method: One Hundred and Eighty Four (184) patients were recruited with confirmed HIV positive status. Investigation was done by serology using the Human Adenovirus IgG ELISA Kit to test for the presence of the Immunoglobulin G (antibody) against the virus. This was conducted and juxtaposed simultaneously with responses received from the questionnaires provided to each participant to correlate the relationship of the co-infections to their socio-demographic factors (Age, Gender, Occupation and location of residence), risk factors (Average hours of exposure per day (time spent outdoor daily), proximity of their apartments to livestock settlements), recent occurrence of respiratory tract infections/conjunctivitis and their ART status.

Results: This study recorded a prevalent rate of 38% (70 patients) to the co-infections. Nevertheless, 62% (114 patients) tested negative to the co-infections.

Conclusion: There was statistical significance between the ages of HIV patients and Adenovirus co-infection (p<0.05). However, there was no significance with respect to gender of the subjects (p>0.05). The findings also showed that there were statistical significance for all the risk factors; Occupation, Location and Proximity to Livestock settlement, recent respiratory tract infection/conjunctivitis, and ART status in relation to Adenovirus and HIV co-infections (p<0.05).

Show MeSH
Related in: MedlinePlus