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Reduction of urogenital schistosomiasis with an integrated control project in Sudan.

Lee YH, Jeong HG, Kong WH, Lee SH, Cho HI, Nam HS, Ismail HA, Alla GN, Oh CH, Hong ST - PLoS Negl Trop Dis (2015)

Bottom Line: Also, a drinking water facility was constructed at Al Hidaib village, where infection rate was reduced more compared to that in a neighboring village within the same unit.However, we found no significant change in the prevalence of S. mansoni infection between baseline and follow-up survey (95% CI = 0.933-6.891).At the end of the project, the prevalence of S. haematobium infection was reduced by more than 50% in comparison with the baseline rate.

View Article: PubMed Central - PubMed

Affiliation: Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, Korea.

ABSTRACT

Purpose: Schistosomiasis remains a major public health concern in Sudan, particularly Schistosoma haematobium infection. This study presents the disease-reduction outcomes of an integrated control program for schistosomiasis in Al Jabalain locality of White Nile State, Sudan from 2009 through 2011.

Methods: The total population of the project sites was 482,902, and the major target group for intervention among them was 78,615 primary school students. For the cross-sectional study of the prevalence, urine and stool specimens were examined using the urine sedimentation method and the Kato cellophane thick smear method, respectively. To assess the impacts of health education for students and a drinking water supply facility at Al Hidaib village, questionnaire survey was done.

Results: The overall prevalence for S. haematobium and S. mansoni at baseline was 28.5% and 0.4%, respectively. At follow-up survey after 6-9 months post-treatment, the prevalence of S. haematobium infection was reduced to 13.5% (95% CI = 0.331-0.462). A higher reduction in prevalence was observed among girls, those with moderately infected status (around 20%), and residents in rural areas, than among boys, those with high prevalence (>40%), and residents in urban areas. After health education, increased awareness about schistosomiasis was checked by questionnaire survey. Also, a drinking water facility was constructed at Al Hidaib village, where infection rate was reduced more compared to that in a neighboring village within the same unit. However, we found no significant change in the prevalence of S. mansoni infection between baseline and follow-up survey (95% CI = 0.933-6.891).

Conclusions: At the end of the project, the prevalence of S. haematobium infection was reduced by more than 50% in comparison with the baseline rate. Approximately 200,000 subjects had received either praziquantel therapy, health education, or supply of clean water. To consolidate the achievements of this project, the integrated intervention should be adapted continuously.

No MeSH data available.


Related in: MedlinePlus

Reduction in the prevalence of S. haematobium infection between the baseline and follow-up surveys.The baseline survey was done at 61 primary schools in Al Jabalain locality before treatment, and the follow-up survey was conducted at 12 schools 6–9 months after the chemotherapy. The reduction rates of prevalence were calculated by [(baseline prevalence - follow-up prevalence)/baseline prevalence] ×100. The figure presented the S. haematobium infection rates of total population, total males and total females, and also showed the representative schools according to the reduction rates of prevalence (low, Al Khansa girls and Al Wifak boys; high, Tayba boys and Assalaya East; middle, AbuBaker Alsiddig and Al Hidaib). * P<0.001, significant difference in S. haematobium prevalence between baseline and follow-up surveys.
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pntd-0003423-g006: Reduction in the prevalence of S. haematobium infection between the baseline and follow-up surveys.The baseline survey was done at 61 primary schools in Al Jabalain locality before treatment, and the follow-up survey was conducted at 12 schools 6–9 months after the chemotherapy. The reduction rates of prevalence were calculated by [(baseline prevalence - follow-up prevalence)/baseline prevalence] ×100. The figure presented the S. haematobium infection rates of total population, total males and total females, and also showed the representative schools according to the reduction rates of prevalence (low, Al Khansa girls and Al Wifak boys; high, Tayba boys and Assalaya East; middle, AbuBaker Alsiddig and Al Hidaib). * P<0.001, significant difference in S. haematobium prevalence between baseline and follow-up surveys.

Mentions: To characterize the reduction patterns of urinary schistosomiasis, the changes in prevalence according to school were analyzed. The prevalence was prominently reduced at 11 schools among 12 examined schools after implementation of the project, whereas the prevalence was significantly increased at Khour Ajwal unit at the follow-up survey (OR  = 2.232, 95% CI  = 1.242–4.009, P = 0.007). As shown in Fig. 6, reduction in the prevalence of S. haematobium infection was greater at schools with 20–25% baseline infection rates (Tayba boys and Assalaya East schools) than at those with <15% baseline infection rates (Al Khansa girls and Al Wifak boys schools) or >40% baseline infection rates (Abu Baker Alsiddig and Al Hidaib schools). The prevalence reduction of the other schools was between 34.4% and 79.1% than that of Khour Ajwal school. According to the sex, the reduction rate of S. haematobium prevalence was greater in girls (61.8%) than that in boys (50.0%).


Reduction of urogenital schistosomiasis with an integrated control project in Sudan.

Lee YH, Jeong HG, Kong WH, Lee SH, Cho HI, Nam HS, Ismail HA, Alla GN, Oh CH, Hong ST - PLoS Negl Trop Dis (2015)

Reduction in the prevalence of S. haematobium infection between the baseline and follow-up surveys.The baseline survey was done at 61 primary schools in Al Jabalain locality before treatment, and the follow-up survey was conducted at 12 schools 6–9 months after the chemotherapy. The reduction rates of prevalence were calculated by [(baseline prevalence - follow-up prevalence)/baseline prevalence] ×100. The figure presented the S. haematobium infection rates of total population, total males and total females, and also showed the representative schools according to the reduction rates of prevalence (low, Al Khansa girls and Al Wifak boys; high, Tayba boys and Assalaya East; middle, AbuBaker Alsiddig and Al Hidaib). * P<0.001, significant difference in S. haematobium prevalence between baseline and follow-up surveys.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4288734&req=5

pntd-0003423-g006: Reduction in the prevalence of S. haematobium infection between the baseline and follow-up surveys.The baseline survey was done at 61 primary schools in Al Jabalain locality before treatment, and the follow-up survey was conducted at 12 schools 6–9 months after the chemotherapy. The reduction rates of prevalence were calculated by [(baseline prevalence - follow-up prevalence)/baseline prevalence] ×100. The figure presented the S. haematobium infection rates of total population, total males and total females, and also showed the representative schools according to the reduction rates of prevalence (low, Al Khansa girls and Al Wifak boys; high, Tayba boys and Assalaya East; middle, AbuBaker Alsiddig and Al Hidaib). * P<0.001, significant difference in S. haematobium prevalence between baseline and follow-up surveys.
Mentions: To characterize the reduction patterns of urinary schistosomiasis, the changes in prevalence according to school were analyzed. The prevalence was prominently reduced at 11 schools among 12 examined schools after implementation of the project, whereas the prevalence was significantly increased at Khour Ajwal unit at the follow-up survey (OR  = 2.232, 95% CI  = 1.242–4.009, P = 0.007). As shown in Fig. 6, reduction in the prevalence of S. haematobium infection was greater at schools with 20–25% baseline infection rates (Tayba boys and Assalaya East schools) than at those with <15% baseline infection rates (Al Khansa girls and Al Wifak boys schools) or >40% baseline infection rates (Abu Baker Alsiddig and Al Hidaib schools). The prevalence reduction of the other schools was between 34.4% and 79.1% than that of Khour Ajwal school. According to the sex, the reduction rate of S. haematobium prevalence was greater in girls (61.8%) than that in boys (50.0%).

Bottom Line: Also, a drinking water facility was constructed at Al Hidaib village, where infection rate was reduced more compared to that in a neighboring village within the same unit.However, we found no significant change in the prevalence of S. mansoni infection between baseline and follow-up survey (95% CI = 0.933-6.891).At the end of the project, the prevalence of S. haematobium infection was reduced by more than 50% in comparison with the baseline rate.

View Article: PubMed Central - PubMed

Affiliation: Department of Infection Biology, Chungnam National University School of Medicine, Daejeon, Korea.

ABSTRACT

Purpose: Schistosomiasis remains a major public health concern in Sudan, particularly Schistosoma haematobium infection. This study presents the disease-reduction outcomes of an integrated control program for schistosomiasis in Al Jabalain locality of White Nile State, Sudan from 2009 through 2011.

Methods: The total population of the project sites was 482,902, and the major target group for intervention among them was 78,615 primary school students. For the cross-sectional study of the prevalence, urine and stool specimens were examined using the urine sedimentation method and the Kato cellophane thick smear method, respectively. To assess the impacts of health education for students and a drinking water supply facility at Al Hidaib village, questionnaire survey was done.

Results: The overall prevalence for S. haematobium and S. mansoni at baseline was 28.5% and 0.4%, respectively. At follow-up survey after 6-9 months post-treatment, the prevalence of S. haematobium infection was reduced to 13.5% (95% CI = 0.331-0.462). A higher reduction in prevalence was observed among girls, those with moderately infected status (around 20%), and residents in rural areas, than among boys, those with high prevalence (>40%), and residents in urban areas. After health education, increased awareness about schistosomiasis was checked by questionnaire survey. Also, a drinking water facility was constructed at Al Hidaib village, where infection rate was reduced more compared to that in a neighboring village within the same unit. However, we found no significant change in the prevalence of S. mansoni infection between baseline and follow-up survey (95% CI = 0.933-6.891).

Conclusions: At the end of the project, the prevalence of S. haematobium infection was reduced by more than 50% in comparison with the baseline rate. Approximately 200,000 subjects had received either praziquantel therapy, health education, or supply of clean water. To consolidate the achievements of this project, the integrated intervention should be adapted continuously.

No MeSH data available.


Related in: MedlinePlus