Unexplained syncope: implications of age and gender on patient characteristics and evaluation, the diagnostic yield of an implantable loop recorder, and the subsequent treatment.
Bottom Line: Muscle spasms or grand mal seizures were more common in men and at <65 years old.There were no age- or gender-related differences in the diagnostic yield of the ILR, whereas patients ≥65 years old more often received specific treatment based on ILR data.Gender and/or age had relevance for the clinical evaluation, rate of recurrence, and subsequent specific treatment but not for the diagnostic yield of the ILR.
Affiliation: Division of Cardiology, Sahlgrenska Academy at Sahlgrenska University Hospital, Göteborg, Sweden.Show MeSH
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Mentions: Five hundred seventy patients were enrolled, 306 (54%) were women and 264 (46%) were men, with a mean age of 62 ± 18 and 60 ± 17 years, respectively. Women more often had syncope associated with severe trauma than men (41% vs 30%, P = 0.007) without any relation to age. Hospitalization because of syncope was of similar frequency in men and women (71% vs 69%, not significant) but was more common in patients ≥65 years than in younger patients (P = 0.03). The actual age at first syncope was 41 ± 17 vs 69 ± 13 years (P < 0.0001) in the <65 and ≥65 year groups, respectively. The average follow-up time was 10 ± 6 months. There were 3 age peaks in men, at about 20, 60, and 80 years, the latter being the highest. The curve for women was similar, except that the latter 2 peaks seem to have merged into 1 somewhat delayed peak at 60 to 80 years (Figure 1).
Affiliation: Division of Cardiology, Sahlgrenska Academy at Sahlgrenska University Hospital, Göteborg, Sweden.