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The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method.

Kamali H, Aminimoghadamfarouj N, Golmakani E, Nematollahi A - Pharmacognosy Res (2015 Jan-Mar)

Bottom Line: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique.Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic).The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

View Article: PubMed Central - PubMed

Affiliation: Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd, Iran.

ABSTRACT

Aim: The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method.

Materials and methods: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique.

Results: Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic).

Conclusion: The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

No MeSH data available.


Observed SC extraction yield versus SC predicted extraction yield
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Figure 5: Observed SC extraction yield versus SC predicted extraction yield

Mentions: The response surface model which was obtained from an experimental design was evaluated using ANOVA and analysis of residuals. The results of the statistical analyses including the t-test and P values of the extraction yield were tabulated in Table 6. The R2 adjusted of the extraction yield was 95.31. This means that the developed models have been able to fully predict the extraction yield. The linear regression coefficients; R2 for the SC yield was also 97.50 as shown in Figure 5, which shows good performance of the model based on the observed and predicted yields. Based on the statistical results (ANOVA) with confidence level of 95%, the effect of each term in the models could be significant provided that its P value be smaller than 0.05 (P < 0.05) is shown in Table 6. It is imperative to realize that even though P value > 0.05 [Table 6] for the linear term of ts but due to Hierarchy rule in which the P value < 0.05 for the higher order (quadratic) of this variable.Table 6


The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method.

Kamali H, Aminimoghadamfarouj N, Golmakani E, Nematollahi A - Pharmacognosy Res (2015 Jan-Mar)

Observed SC extraction yield versus SC predicted extraction yield
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4285650&req=5

Figure 5: Observed SC extraction yield versus SC predicted extraction yield
Mentions: The response surface model which was obtained from an experimental design was evaluated using ANOVA and analysis of residuals. The results of the statistical analyses including the t-test and P values of the extraction yield were tabulated in Table 6. The R2 adjusted of the extraction yield was 95.31. This means that the developed models have been able to fully predict the extraction yield. The linear regression coefficients; R2 for the SC yield was also 97.50 as shown in Figure 5, which shows good performance of the model based on the observed and predicted yields. Based on the statistical results (ANOVA) with confidence level of 95%, the effect of each term in the models could be significant provided that its P value be smaller than 0.05 (P < 0.05) is shown in Table 6. It is imperative to realize that even though P value > 0.05 [Table 6] for the linear term of ts but due to Hierarchy rule in which the P value < 0.05 for the higher order (quadratic) of this variable.Table 6

Bottom Line: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique.Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic).The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

View Article: PubMed Central - PubMed

Affiliation: Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd, Iran.

ABSTRACT

Aim: The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method.

Materials and methods: Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique.

Results: Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic).

Conclusion: The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

No MeSH data available.